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Sterilizing composition with synergistic effect and use thereof

A synergistic effect and composition technology, applied in the direction of application, fungicide, biocide, etc., can solve the problem of drug resistance of bacteria, achieve the effects of delaying the generation of drug resistance, increasing safety, and good bactericidal effect

Inactive Publication Date: 2017-06-06
INST OF PLANT PROTECTION CHINESE ACAD OF AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its mechanism of action is unique, highly efficient, slightly toxic, and pollution-free. It has a high control effect on plant diseases caused by various pathogenic fungi, but long-term single use will inevitably make the bacteria resistant to it.
[0006] So far, there is no report that hymexazol and Cyazofamid can be compounded to effectively control soil-borne diseases

Method used

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  • Sterilizing composition with synergistic effect and use thereof
  • Sterilizing composition with synergistic effect and use thereof
  • Sterilizing composition with synergistic effect and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Determination of the toxicity of hymexazol and cyafamid to Fusarium oxysporum, the test object is Fusarium oxysporum, and the indoor bioassay is carried out according to the above test method, and the treatment without the drug is used as the blank control, and repeated three times. The test results are shown in Table 1 below.

[0040] Table 1 Toxicity of hymexazol and cyafamid to Fusarium oxysporum

[0041] Reagent Regression equation (Y=) Correlation coefficient R EC 50 (μg / mL)

[0042] Toxicity assay result table 1 shows, in the scope of weight ratio 5:1-1:5 the synergistic coefficient of hymexazol and cyafamid composition is all greater than 1.5, has obvious synergism to the control ability of Fusarium oxysporum Synergistic effect, excellent control effect and better than single agent varieties.

Embodiment 2

[0044] Determination of the toxicity of hymexazol and cyazazole to Pythium melon and fruit. The test object is Pythium melon and fruit. The indoor bioassay was carried out according to the above test method. The treatment without the drug was used as the blank control and repeated three times. The test results are shown in Table 2 below.

[0045] Table 2 Toxicity of Hymexazol and Cyazofamid to Pythium melon

[0046] Reagent Regression equation (Y=) Correlation coefficient R EC 50 (μg / mL)

Synergy factor Hymexazol A 2.0613+1.1407x 0.9981 23.59 -- Cyazofamid B 5.1699+0.6275x 0.9979 0.54 -- A+B(5:1) 4.7980+0.6019x 0.9919 1.91 1.52 A+B(3:1) 4.9357+0.7029x 0.9885 1.23 1.64 A+B(3:2) 5.1087+1.1282x 0.9957 0.80 1.63 A+B(1:1) 51467+0.5298x 0.998 0.53 1.99 A+B(2:3) 5.2436+0.6898x 0.9919 0.44 2.01 A+B(1:3) 5.2230+0.6328x 0.9936 0.44 1.62 A+B(1:5) 5.3432+0.6767x 0.9922 0.31 2.08

[004...

preparation Embodiment

[0050] Formulation Example 1 40% Hymexazol Cyazofamid Suspension Concentrate (20% Hymexazol and 20% Cyazofamid)

[0051] 20% hymexazol, 20% cyanazazole, 6% sodium lignosulfonate, 2% JFC (fatty alcohol polyoxyethylene ether), 0.2% xanthan gum, 1% magnesium aluminum silicate, 4% ethylene glycol Alcohol and the remaining water are subjected to high-speed shearing, sanding with wet hair, and finally homogeneous filtration to obtain the product.

[0052] Formulation Example 2 50% Hymexazol · Cyanazazole WP (30% Hymexazol and 20% Cyazofamid)

[0053] 30% Hymexazol, 20% Cyazofamid, 1% Sodium Lauryl Sulfate, 1.5% Open Powder, 3% Sodium Lignosulfonate, 3% NNO (naphthalenesulfonate formaldehyde condensate), 10 % white carbon black and the rest of kaolin are mixed in proportion, and then mixed to obtain a wettable powder after jet crushing.

[0054] Formulation Example 3 50% Hymexazol Cyazofamid Water-Dispersible Granules (30% Hymexazol and 20% Cyazofamid)

[0055] 30% Hymexazol, 20% ...

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PUM

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Abstract

The invention discloses a sterilizing composition with a synergistic effect and use thereof. The sterilizing composition comprises the active ingredients of hymexazol and cyazofamid in a weight ratio of 1: 50 to 50: 1. The sterilizing composition can obviously improve the preventing and treating effect of soil-borne diseases and is obvious in synergic effect, so that the number of times of application is reduced, and therefore, the using cost is lowered, the time and labor are saved, and the sterilizing composition has obvious economical and social benefits, and meanwhile, pesticide resistance is delayed.

Description

technical field [0001] The invention belongs to the field of plant protection, and in particular relates to a fungicidal composition with synergistic effect and its application. Background technique [0002] Soil-borne diseases refer to diseases caused by soil-borne pathogens living in the soil with diseased residues and invading crops from roots or stems when conditions are suitable, such as rice sheath blight, rice false smut, bakanae disease, and corn spot disease, soybean root rot, cotton blight, peanut bacterial wilt, etc. Soil-borne pathogens include fungi, bacteria, actinomycetes, nematodes, etc., mainly fungi, and soil-borne pathogenic fungi are divided into non-obligate parasitism and obligate parasitism, of which non-obligate parasitism is exogenous root infection Fungi, such as Pythium cause seedling rot and damping-off, Rhizoctonia cause seedling blight; obligate parasitism is the pathogenic fungus of plant microtubule bundles, typically Fusarium oxysporum, Vert...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N43/80A01N43/50A01P3/00
CPCA01N43/80A01N43/50A01N2300/00
Inventor 闫晓静袁会珠杨代斌李庆杨利娟
Owner INST OF PLANT PROTECTION CHINESE ACAD OF AGRI SCI
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