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Medicine composition for treating tuberculous pleuritis, and preparation method and application thereof

A technology for tuberculous pleurisy and a composition, applied in the field of medicine, can solve the problems of unsatisfactory curative effect, large side effects, good curative effect and the like, and achieve the effects of no toxic side effects and allergic reactions, low recurrence rate and quick effect.

Inactive Publication Date: 2017-05-31
ZHENGZHOU ZHANGMENG NETWORK TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Traditional Chinese medicine has achieved good curative effect in the treatment of this disease, but there are still some problems: clinically, the curative effect obtained in reducing the adverse reaction of pleural effusion absorption and shortening the course of the disease is not satisfactory.
The curative effect of western medicine is good, the side effect is big

Method used

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  • Medicine composition for treating tuberculous pleuritis, and preparation method and application thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] In an embodiment of the present invention, a pharmaceutical composition for treating tuberculous pleurisy is composed of the following raw materials in parts by weight: 1 part of allicin, 3 parts of cyproheptadine, 15 parts of Pueraria flavone, and 11 parts of cefuroxime.

[0018] Mix and grind cyproheptadine and cefuroxime, add 6.2 times the mass of deionized water, and stir at 66° C. for 48 minutes to prepare mixture A. Mix kudzu flavonoids with mixture A, stir at 60°C for 23 minutes, add allicin, then ultrasonically treat at 43°C for 33 minutes, ultrasonic power is 800W, and then stir at 55°C until dry. Granulation to obtain the pharmaceutical composition.

Embodiment 2

[0020] In an embodiment of the present invention, a pharmaceutical composition for treating tuberculous pleurisy is composed of the following raw materials in parts by weight: 3 parts of allicin, 7 parts of cyproheptadine, 23 parts of Pueraria flavone, and 19 parts of cefuroxime.

[0021] Mix and grind cyproheptadine and cefuroxime, add deionized water 6.2 times the mass of the two, and stir at 66° C. for 50 minutes to prepare mixture A. Mix Pueraria flavonoids with mixture A, stir at 60°C for 25 minutes, add allicin, then ultrasonically treat at 43°C for 33 minutes, ultrasonic power is 800W, and then stir at 55°C until dry. Granulation to obtain the pharmaceutical composition.

Embodiment 3

[0023] In an embodiment of the present invention, a pharmaceutical composition for treating tuberculous pleurisy is composed of the following raw materials in parts by weight: 1.5 parts of allicin, 4 parts of cyproheptadine, 17 parts of Pueraria flavonoids, and 13 parts of cefuroxime.

[0024] Mix and grind cyproheptadine and cefuroxime, add deionized water 6.2 times the mass of the two, and stir at a temperature of 66°C for 49 minutes to prepare a mixture A. Mix kudzu flavonoids with mixture A, stir at 60°C for 24min, add allicin, then ultrasonicate at 43°C for 33min, ultrasonic power is 800W, then stir at 55°C until dry. Granulation to obtain the pharmaceutical composition.

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Abstract

The invention discloses a medicine composition for treating tuberculous pleuritis, and a preparation method and application thereof. The medicine composition is prepared from the following raw materials in parts by weight: 1 to 3 parts of allicin, 3 to 7 parts of cyproheptadine, 15 to 23 parts of radix puerariae flavone, and 11 to 19 parts of cefuroxime. The preparation method comprises the steps of mixing and grinding the cyproheptadine and the cefuroxime, adding deionized water, stirring for 48 to 50 min at the temperature of 66 DEG C, and preparing a mixture A; mixing the radix puerariae flavone and the mixture A, stirring for 23 to 25 min at the temperature of 60 DEG C, adding the allicin, then carrying out ultrasonic treatment for 33 min at the temperature of 43 DEG C, stirring at the temperature of 55 DEG C until dry, and pelleting. The medicine composition for treating tuberculous pleuritis provided by the invention is remarkable in treatment effect, high in cure rate, short in treatment time, fast in effect, free of toxic and side effect and anaphylactic reaction, high in cure rate, low in recurrence rate, low in cost, and less in dosage, and is a more ideal medicine.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a pharmaceutical composition for treating tuberculous pleurisy and its preparation method and application. Background technique [0002] Tuberculous pleurisy is a pleural inflammation caused by Mycobacterium tuberculosis and its autolyzed products and metabolites entering the pleural cavity of ultra-sensitive organisms. Tuberculous pleurisy is the disease caused by Mycobacterium tuberculosis first invading the body. The majority of tuberculous pleurisy in my country is caused by Mycobacterium tuberculosis. Most tuberculous pleurisy is acute. The symptoms are mainly systemic poisoning symptoms of tuberculosis and local symptoms caused by pleural effusion. The symptoms of tuberculosis poisoning are mainly manifested as fever, chills, sweating, fatigue, loss of appetite, and night sweats. Local symptoms include chest pain, dry cough, and dyspnea. Chest pain is usually located ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/488A61P31/06A61K31/546A61K31/4418A61K31/255
CPCA61K31/255A61K31/4418A61K31/546A61K36/488
Inventor 不公告发明人
Owner ZHENGZHOU ZHANGMENG NETWORK TECH CO LTD
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