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Uniformly-degradable polylactic acid based intravascular stent

A vascular stent and polylactic acid-based technology, which is applied in the field of interventional treatment equipment for cardiovascular diseases, can solve problems such as uneven degradation of degradable stents, and achieve the effects of prolonging the overall support time, reducing the extreme value of stent stress, and uniform stent stress distribution

Inactive Publication Date: 2017-05-31
BEIHANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] In order to solve the problem of uneven degradation of current degradable stents, the present invention designs a uniformly degradable polylactic acid-based vascular stent according to the influence of stress on the degradation rate of polylactic acid materials

Method used

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  • Uniformly-degradable polylactic acid based intravascular stent
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  • Uniformly-degradable polylactic acid based intravascular stent

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Embodiment Construction

[0014] Below in conjunction with accompanying drawing and specific embodiment the present invention will be further described:

[0015] A uniformly degradable polylactic acid-based vascular stent according to the present invention is made of polylactic acid or polylactic acid-glycolic acid copolymer, such as figure 1 As shown, the entire scaffold is a tubular network structure, including multiple repeating units. The part framed by the black dotted line in the figure is a part of the repeating unit; each repeating unit is composed of a main support ring and 3 linear connecting ribs. That is, every two adjacent main support rings are connected by 3 linear connecting ribs evenly distributed along the circumference; the range of the radius of the main support ring is 1-3 mm, that is, the range of the radius of the vascular stent is 1-3 mm , the length of the linear connecting rib is 1.5 to 2 times the radius of the main supporting ring.

[0016] The center of the main support ri...

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Abstract

The invention relates to the field of interventional therapy equipment for cardiovascular diseases and discloses a uniformly-degradable polylactic acid based intravascular stent. The intravascular stent comprises body supporting rings and linear connection ribs, each body supporting ring comprises six wave peaks and six wave troughs, the wave peaks and the wave troughs of every two adjacent body supporting rings are in staggered arrangement, the wave peaks of each body supporting ring correspond to the wave troughs of the next body supporting ring, every two adjacent body supporting rings are connected through three of the linear connection ribs at equal intervals, and connection points are closer peak-trough points. Reinforcement structures are additionally provided for other peak-trough arc portions without connection points, and every two adjacent arc structures are connected through an 'N'-shaped line. The uniformly-degradable polylactic acid based intravascular stent has advantages that stent size parameters are optimized reasonably, stent stress extreme values are decreased while stent supporting strength is guaranteed, high stress distribution uniformity of the stent is realized, degradation uniformity is achieved, and integral supporting time of the stent is prolonged.

Description

technical field [0001] The invention relates to the field of interventional treatment equipment for cardiovascular diseases, belongs to the category of completely biodegradable heart stents, and specifically relates to a polylactic acid-based vascular stent capable of uniform degradation. Background technique [0002] Inserting intravascular stents in narrowed or blocked blood vessels is one of the important methods currently used to treat cardiovascular diseases. Biodegradable stents can provide effective support after being implanted in human diseased blood vessels, and gradually degrade and absorb after vascular reconstruction is completed, which can effectively avoid biocompatibility problems and vascular inflammatory reactions caused by permanent stents. [0003] However, the current degradable stents are still not perfect. Studies have shown that stress has a significant impact on the degradation rate of degradable materials. After the stent is implanted in the blood v...

Claims

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Application Information

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IPC IPC(8): A61F2/915A61L31/14A61L31/06
CPCA61F2/915A61F2002/91575A61F2210/0004A61F2230/0002A61L31/06A61L31/148C08L67/04
Inventor 樊瑜波郭萌储照伟
Owner BEIHANG UNIV
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