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Noninvasive blood glucose testing device based on human-eye iris reflection aqueous humor near infrared spectrum

A near-infrared spectroscopy and near-infrared spectrometer technology, applied in the directions of diagnostic recording/measurement, medical science, diagnosis, etc., can solve the problems of low lens reflectivity, influence of detection accuracy, high cost, etc., to eliminate infection risks and ensure accuracy. , the effect of reducing discomfort

Inactive Publication Date: 2017-05-24
NANJING UNIV OF SCI & TECH
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Problems solved by technology

Existing non-invasive testing instruments mostly select fingers, earlobes, palms and other parts as detection objects. Although these parts contain blood sugar composition information, the measurement accuracy is very low due to the complexity of its tissue composition and the great influence of body temperature and human body function status. Difficult to guarantee
[0004] In the article "Non-invasive glucose determination in the human eye", Wolfgang Schrader from the University of Wurzburg in Germany took aqueous humor as the detection object and established a non-invasive blood glucose detection system. They chose the light reflected from the lens surface as the detection spectrum, but due to The reflectivity of the lens is very low, so the signal-to-noise ratio of the acquired spectral signal is low, and the detection accuracy is greatly affected
[0005] Existing non-invasive blood glucose detection devices are bulky, have low detection accuracy, and are relatively expensive

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  • Noninvasive blood glucose testing device based on human-eye iris reflection aqueous humor near infrared spectrum
  • Noninvasive blood glucose testing device based on human-eye iris reflection aqueous humor near infrared spectrum
  • Noninvasive blood glucose testing device based on human-eye iris reflection aqueous humor near infrared spectrum

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Embodiment 1

[0045] combine figure 1 with figure 2 , a non-invasive blood glucose detection device based on the near-infrared spectrum reflected by the iris of the human eye in the present invention, comprising a tungsten-halogen lamp 1, a band-pass filter 2, a gaze target 3, a near-infrared spectrometer 4, a data processing module 5, and a human eye Near-infrared spectrum prediction mathematical model module 6 and LED screen 7 for glucose content in aqueous humor. The band-pass filter 2 is set at the light outlet of the tungsten-halogen lamp 1, the gaze target 3 is located directly in front of the human eye, the halogen tungsten lamp 1 and the near-infrared spectrometer 4 are respectively located on both sides of the gaze target 3, the near-infrared spectrometer 4, data processing Module 5, human eye aqueous humor glucose content near-infrared spectrum prediction mathematical model module 6 and LED screen 7 are connected in sequence. The tungsten-halogen lamp 1 generates a continuous n...

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Abstract

The invention discloses a noninvasive blood glucose testing device based on human-eye iris reflection aqueous humor near infrared spectrum. The noninvasive blood glucose testing device comprises a halogen tungsten lamp, a band-pass filter, a gazing target, a near infrared spectrometer, a data processing module, a human-eye aqueous humor glucose content near infrared spectrum predicting mathematic model module and an LED screen. Continuous near infrared light beams generated by the halogen tungsten lamp pass the band-pass filter and are obliquely injected into human eyes; the continuous near infrared light beams pass human corneas and are subjected to aqueous humor transmission and iris reflection, and the emergent near infrared light contains the glucose content information in aqueous humor; the near infrared spectrometer collects and analyzes the emergent near infrared light to obtain the spectrum data information of the emergent near infrared light and transmits the spectrum data information into the data processing module; the data processing module preprocesses the spectrum data information and transmits the preprocessed data into the human-eye aqueous humor glucose content near infrared spectrum predicting mathematic model to obtain an accurate blood glucose value, and the accurate blood glucose value is displayed on the LED screen. The noninvasive blood glucose testing device has the advantages that the signal-to-noise ratio of the incident signals of the near infrared spectrometer is increased, and the accuracy of blood glucose testing is increased.

Description

technical field [0001] The invention belongs to the field of biological tissue parameter detection, and relates to a non-invasive blood sugar detection device based on the near-infrared spectrum of aqueous humor reflected by the iris of the human eye. Background technique [0002] Diabetes mellitus is a metabolic disease characterized by hyperglycemia caused by defects in insulin secretion or biological action. It is one of the most important chronic non-communicable diseases currently threatening human health worldwide. Currently, most self-monitoring glucometers use a minimally invasive method of blood glucose testing that is both painful for the patient and increases the risk of infection. [0003] Chinese patent 201519152.1 discloses a "non-invasive blood sugar detection system", which includes a light source module, a light transmission module, a light detection module and a data processing module. The system can detect blood sugar in either transmission or reflection....

Claims

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Application Information

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IPC IPC(8): A61B5/1455
Inventor 高志山朱丹陈玥洋袁群窦健泰杨忠明王帅成金龙
Owner NANJING UNIV OF SCI & TECH
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