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Medicine composition for treating tuberculous pleurisy, method for preparing medicine composition and application thereof

A tuberculous pleurisy and composition technology, applied in the field of medicine, can solve the problems of large side effects, good curative effect, and unsatisfactory curative effect, and achieve the effects of low recurrence rate, quick effect, no toxic side effects and allergic reactions

Inactive Publication Date: 2017-05-10
郑州莉迪亚医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Traditional Chinese medicine has achieved good curative effect in the treatment of this disease, but there are still some problems: clinically, the curative effect obtained in reducing the adverse reaction of pleural effusion absorption and shortening the course of the disease is not satisfactory.
The curative effect of western medicine is good, the side effect is big

Method used

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  • Medicine composition for treating tuberculous pleurisy, method for preparing medicine composition and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0017] In an embodiment of the present invention, a pharmaceutical composition for treating tuberculous pleurisy consists of the following raw materials in parts by weight: 1 part of artemisinin, 3 parts of cyproheptadine, 15 parts of taurine, and 11 parts of cefuroxime.

[0018] Mix and grind cyproheptadine and cefuroxime, add 6.2 times the mass of deionized water, and stir at 66° C. for 48 minutes to prepare mixture A. Mix taurine with mixture A, stir at 60°C for 23min, add artemisinin, then ultrasonicate at 43°C for 33min, ultrasonic power is 800W, then stir at 55°C until Dried and granulated to obtain the pharmaceutical composition.

Embodiment 2

[0020] In an embodiment of the present invention, a pharmaceutical composition for treating tuberculous pleurisy is composed of the following raw materials in parts by weight: 3 parts of artemisinin, 7 parts of cyproheptadine, 23 parts of taurine, and 19 parts of cefuroxime.

[0021] Mix and grind cyproheptadine and cefuroxime, add deionized water 6.2 times the mass of the two, and stir at 66° C. for 50 minutes to prepare mixture A. Mix taurine with mixture A, stir at 60°C for 25min, add artemisinin, then ultrasonicate at 43°C for 33min, ultrasonic power is 800W, then stir at 55°C until Dried and granulated to obtain the pharmaceutical composition.

Embodiment 3

[0023] In an embodiment of the present invention, a pharmaceutical composition for treating tuberculous pleurisy is composed of the following raw materials in parts by weight: 1.5 parts of artemisinin, 4 parts of cyproheptadine, 17 parts of taurine, and 13 parts of cefuroxime.

[0024] Mix and grind cyproheptadine and cefuroxime, add deionized water 6.2 times the mass of the two, and stir at a temperature of 66°C for 49 minutes to prepare a mixture A. Mix taurine with mixture A, stir at 60°C for 24min, add artemisinin, then sonicate at 43°C for 33min, ultrasonic power is 800W, then stir at 55°C until Dried and granulated to obtain the pharmaceutical composition.

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Abstract

The invention discloses a medicine composition for treating tuberculous pleurisy, a method for preparing the medicine composition and application thereof. The medicine composition comprises, by weight, 1-3 parts of artemisinin, 3-7 parts of cyproheptadine, 15-23 parts of taurine and 11-19 parts of cefuroxime. The method includes mixing and grinding the cyproheptadine and the cefuroxime with each other, adding deionized water into the cyproheptadine and the cefuroxime and stirring and treating the deionized water, the cyproheptadine and the cefuroxime at the temperature of 66 DEG C for 48-50 min to obtain mixtures A; mixing the taurine and the mixtures A with one another, stirring and treating the taurine and the mixtures A at the temperature of 60 DEG C for 23-25 min, adding the artemisinin into the taurine and the mixtures A to obtain other mixtures, carrying out ultrasonic treatment on the other mixtures at the temperature of 43 DEG C for 33 min, then stirring the other mixtures at the temperature of 55 DEG C until the other mixtures are dried and granulating the other mixtures to obtain the medicine composition. The medicine composition, the method and the application have the advantages that the medicine composition can be used for treating the tuberculous pleurisy, is high in cure rate, short in treatment time, free of toxic and side effects or allergic reaction and low in manufacturing cost and dosage, can become effective fast and is a perfect medicine, obvious treatment effects can be realized, and the tuberculous pleurisy is low in recurrence rate.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a pharmaceutical composition for treating tuberculous pleurisy and its preparation method and application. Background technique [0002] Tuberculous pleurisy is a pleural inflammation caused by Mycobacterium tuberculosis and its autolyzed products and metabolites entering the pleural cavity of ultra-sensitive organisms. Tuberculous pleurisy is the disease caused by Mycobacterium tuberculosis first invading the body. The majority of tuberculous pleurisy in my country is caused by Mycobacterium tuberculosis. Most tuberculous pleurisy is acute. The symptoms are mainly systemic poisoning symptoms of tuberculosis and local symptoms caused by pleural effusion. The symptoms of tuberculosis poisoning are mainly manifested as fever, chills, sweating, fatigue, loss of appetite, and night sweats. Local symptoms include chest pain, dry cough, and dyspnea. Chest pain is usually located ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/546A61P31/06A61P29/00A61P11/00A61K31/4418A61K31/366A61K31/185
CPCA61K31/546A61K31/185A61K31/366A61K31/4418A61K2300/00
Inventor 不公告发明人
Owner 郑州莉迪亚医药科技有限公司
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