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A kind of Ganoderma lucidum tablet and preparation method thereof

A technology of Ganoderma lucidum and tablets, which is applied in the direction of anti-toxic agents, anti-inflammatory agents, and pill delivery. It can solve the problems of safety hazards, reduce the proportion of active ingredients, and less pharmacological efficacy, so as to improve safety, increase the content of active ingredients, and improve product quality. The effect of index stabilization

Active Publication Date: 2019-07-12
仙芝科技(福建)股份有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the pharmacological efficacy of a single ingredient is relatively small, the addition of excipients will reduce the proportion of active ingredients in the tablet, and at the same time, it will often bring some safety hazards due to the quality of domestically produced excipients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0019] A preparation method of ganoderma lucidum tablet, comprising the following steps:

[0020] 1 Preparation of Ganoderma lucidum fruiting body powder: Ganoderma lucidum fruiting body is dried until the water content is lower than 3%, crushed and sieved to 100 meshes to obtain Ganoderma lucidum fruiting body powder;

[0021] 2 Preparation of Ganoderma lucidum alcohol extract powder: 100 parts of Ganoderma lucidum fruiting body crushed to 20 mesh, extracted with 20 times 70% ethanol, filtered to get the filtrate, and the filter residue was extracted with 20 times 70% ethanol, repeated 2 times, combined 3 times filtrate, concentrated to The weight is one-fifth of the weight of the original Ganoderma fruiting body, and the powder obtained by adding 2 parts of Ganoderma lucidum fruiting body powder to dry and pulverize is Ganoderma lucidum alcohol extract powder, wherein the content of Ganoderma lucidum triterpenoids is greater than 18%;

[0022] 3 Preparation of Ganoderma luci...

Embodiment 1

[0030] Embodiment 1, raw material preparation:

[0031] 1. Ganoderma lucidum fruiting body powder: Ganoderma lucidum fruiting body is dried until the water content is lower than 3%, crushed and sieved to 100 meshes to obtain Ganoderma lucidum fruiting body powder;

[0032] 2. Ganoderma lucidum alcohol extract powder: 100kg of Ganoderma lucidum fruiting body is crushed to 20 meshes, added 2 tons of 70% ethanol for extraction, filtered to get the filtrate, and the filter residue is extracted with 2 tons of 70% ethanol, repeated 2 times, and the filtrate was combined 3 times, Concentrate until the weight is one-fifth of the weight of the original Ganoderma lucidum fruiting body, that is, 20kg, add 2kg of Ganoderma lucidum fruiting body powder as described in step 1, dry until the water content is lower than 3%, crush and pass through a 100-mesh sieve to obtain the Ganoderma lucidum alcohol extract powder, Ganoderma lucidum triterpenes content 18.1%;

[0033] 3. Ganoderma lucidum w...

Embodiment 2

[0036] Example 2, preparation of tablets: take 300 parts of Ganoderma lucidum alcohol extract powder, 300 parts of Ganoderma lucidum water extract powder, 200 parts of Ganoderma lucidum fruiting body powder, 200 parts of broken Ganoderma lucidum spore powder, mix evenly, sieve 80 meshes, add 800 parts Wet granulation with 65% ethanol, passed through a 20-mesh sieve, dried at 70°C until the moisture content was less than 4%, and passed through a 20-mesh sieve for granulation. All the other undescribed parts are the same as in Example 1.

[0037] Adjust the filling volume and pressure, and start to press the tablet after the tablet weight and hardness meet the standard requirements, check the tablet weight and hardness every 20 minutes, and stop the machine immediately for inspection if any abnormalities such as loose tablets, splits, sticking, excessive difference in tablet weight or discoloration are found Add the compressed plain tablets into a polishing machine, and polish t...

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PUM

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Abstract

The invention discloses a lucid ganoderma tablet and a preparation method of the lucid ganoderma tablet. The lucid ganoderma tablet is prepared from the following components in parts by weight: 50-550 parts of lucid ganoderma alcohol extract powder, 50-550 parts of lucid ganoderma water extract powder, 200 parts of lucid ganoderma sporocarp powder, and 200 parts of broken ganoderma lucidum spore powder. In the process of preparing lucid ganoderma alcohol extract powder and the lucid ganoderma water extract powder, lucid ganoderma sporocarp powder replaces the conventional auxiliary materials including filling and disintegrating agents and lubricant. The lucid ganoderma alcohol extract, the lucid ganoderma water extract, the lucid ganoderma sporocarp and the broken ganoderma lucidum spore powder are mixed, the process is simple and feasible, the active ingredients are diversified and are high in content, the content of ganoderma triterpenes is 1-10 %, the content of ganoderan is 1-12 %, so that the efficacies of the product are improved, the lucid ganoderma alcohol extract powder and the lucid ganoderma water extract powder are taken as adhesives, the lucid ganoderma sporocarp powder and the spore powder are taken as the disintegrating agents, so that the use of the conventional auxiliary materials and the man-made pollution are avoided, the quality stability of the product is improved, and the preservation time of the lucid ganoderma tablet is longer than that of the common capsule, powder and tablet.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine pharmacy and health products, and in particular relates to a ganoderma lucidum tablet and a preparation process thereof. Background technique [0002] Ganoderma lucidum is the fruiting body of the polyporaceae fungus Ganoderma lucidum. It was first recorded in "Shen Nong's Materia Medica", and later included in "Compendium of Materia Medica", and was listed as the top grade, sweet in taste and flat in nature, strengthening the body and strengthening the foundation. The main active ingredients are Ganoderma lucidum triterpenes and Ganoderma lucidum polysaccharides. Ganoderma lucidum triterpenes have pharmacological effects such as anti-tumor, anti-inflammatory, anti-aging and liver protection. Ganoderma lucidum polysaccharide has anti-tumor, immune regulation, anti-oxidation, hypoglycemic and other pharmacological effects. [0003] Most of the preparations of ganoderma lucidum products...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/074A61K9/20A61P37/04A61P35/00A61P29/00A61P39/06A61P1/16A61P37/02A61P3/06
CPCA61K9/2004A61K36/074A61K2236/331A61K2236/333A61K2236/39A61K2236/51
Inventor 李晔周岩飞姚渭溪黄样增朱忠敏
Owner 仙芝科技(福建)股份有限公司
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