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Silk fibroin composite hydrogel applicable to sensitive skins and method for preparing silk fibroin composite hydrogel

A composite hydrogel and silk fibroin technology, which is applied in the field of silk fibroin composite hydrogel and its preparation, can solve the problem that people with sensitive skin cannot be used, and achieve the effects of good moisturizing effect, fast absorption and mild nature.

Inactive Publication Date: 2017-03-15
JIANGSU AIXISHI TECH SERVICE CONSULTATION CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Sensitive skin has high requirements for skin care products and cosmetics, and often causes inflammation due to improper use. In the prior art, aloe vera gel is often used as a skin care product for repairing inflammation, but aloe vera extract itself has molecular crystal phases that can easily cause allergies , so it is not suitable for people with sensitive skin

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A silk fibroin composite hydrogel suitable for sensitive muscles, which is made of the following components in proportion by weight: 23 parts of silk protein, 8 parts of tussah silk protein, 9 parts of collagen, 9 parts of sericin, transparent 13 parts of hyaluronic acid, 3 parts of trehalose, 6 parts of loofah extract, 2 parts of avocado extract, 7 parts of urea, 3 parts of vitamin E, 4 parts of vitamin C, and 20 parts of deionized water.

[0025] A method for preparing a silk fibroin composite hydrogel suitable for sensitive muscles, comprising the following steps:

[0026] (1) Preparation of silk protein: put raw silk in a sodium carbonate solution with a mass concentration of 0.80 g / L, and heat it for 45 minutes at 76°C; take out the silk and rinse it with deionized water, and then wash the silk Put it in a sodium hydroxide solution with a mass concentration of 0.03g / L, heat it at 88°C for 12 minutes, take it out and wash it with deionized water;

[0027] (2) Prepa...

Embodiment 2

[0033] A silk fibroin composite hydrogel suitable for sensitive muscles, which is made of the following components in proportion by weight: 31 parts of silk protein, 15 parts of tussah silk protein, 13 parts of collagen, 18 parts of sericin, transparent 21 parts of hyaluronic acid, 12 parts of trehalose, 9 parts of loofah extract, 7 parts of avocado extract, 13 parts of urea, 8 parts of vitamin E, 8 parts of vitamin C, and 32 parts of deionized water.

[0034] A method for preparing a silk fibroin composite hydrogel suitable for sensitive muscles, comprising the following steps:

[0035] (1) Preparation of silk protein: put raw silk in a sodium carbonate solution with a mass concentration of 0.88g / L, heat it for 52 minutes at 88°C; take out the silk and rinse it with deionized water, and then wash the silk Put it in a sodium hydroxide solution with a mass concentration of 0.09g / L, heat it at 93°C for 18 minutes, take it out and wash it with deionized water;

[0036] (2) Prepa...

Embodiment 3

[0042] A silk fibroin composite hydrogel suitable for sensitive muscles, which is made of the following components in proportion by weight: 36 parts of silk protein, 19 parts of tussah silk protein, 17 parts of collagen, 21 parts of sericin, transparent 25 parts of uric acid, 16 parts of trehalose, 14 parts of loofah extract, 11 parts of avocado extract, 18 parts of urea, 12 parts of vitamin E, 12 parts of vitamin C, and 38 parts of deionized water.

[0043] A method for preparing a silk fibroin composite hydrogel suitable for sensitive muscles, comprising the following steps:

[0044] (1) Preparation of silk protein: put raw silk in a sodium carbonate solution with a mass concentration of 0.96g / L, and heat it for 60 minutes at 95°C; take out the silk and rinse it with deionized water, and then wash the silk Put it in a sodium hydroxide solution with a mass concentration of 0.14g / L, heat it at 100°C for 21 minutes, take it out and wash it with deionized water;

[0045] (2) Pr...

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Abstract

The invention discloses silk fibroin composite hydrogel applicable to sensitive skins and a method for preparing the silk fibroin composite hydrogel. The silk fibroin composite hydrogel comprises, by weight, 23-36 parts of silk proteins, 8-19 parts of tussah silk proteins, 9-17 parts of collagen, 9-21 parts of sericin, 13-25 parts of hyaluronic acid, 3-16 parts of trehalose, 6-14 parts of loofah extract, 2-11 parts of avocado extract, 7-18 parts of urea, 3-12 parts of vitamin E, 4-12 parts of vitamin C and 20-38 parts of deionized water. The silk fibroin composite hydrogel and the method have the advantages that the silk fibroin composite hydrogel is high in absorption speed, and good moisturizing effects can be realized; the silk fibroin composite hydrogel has functions of isolating harmful substances, absorbing ultraviolet rays and the like, and accordingly double skincare and protection effects can be realized; the silk fibroin composite hydrogel is mild in property, free of irritant components and applicable to the sensitive skins.

Description

technical field [0001] The invention belongs to the field of cosmetics and relates to a cosmetic using silk as a raw material, in particular to a silk fibroin composite hydrogel suitable for sensitive muscles and a preparation method thereof. Background technique [0002] With the improvement of people's living standards, cosmetics have almost become an indispensable daily necessities for people, and the requirements for cosmetics are increasingly natural, nutritious, non-irritating and so on. Based on this, the research on the use of silk protein has also received more and more attention. [0003] Used in cosmetics, silk protein is one of the best raw materials in cosmetics at present. It has no toxic and side effects, has good affinity with the human body, has no irritation to the skin, no allergic reaction, and has strong penetration. Some data show that: silk protein can be absorbed by human cells in about 10 seconds; it can also absorb ultraviolet rays and has the effe...

Claims

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Application Information

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IPC IPC(8): A61K8/98A61K8/9789A61K8/42A61K8/60A61K8/64A61K8/65A61K8/67A61K8/73A61Q17/04A61Q19/00
CPCA61K8/987A61K8/42A61K8/60A61K8/64A61K8/65A61K8/676A61K8/678A61K8/735A61K8/97A61K2800/72A61Q17/04A61Q19/00A61Q19/005
Inventor 汪屹
Owner JIANGSU AIXISHI TECH SERVICE CONSULTATION CO LTD
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