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Systems and methods for automated analysis of output in single particle inductively coupled plasma mass spectrometry and similar data sets

An automatic analysis, particle technology, applied to parts of particle separator tubes, analytical materials, particle separation tubes, etc., to solve problems such as inaccuracy, lack of precision and/or reproducibility

Active Publication Date: 2017-02-22
PERKINELMER HEALTH SCIENCES INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Because of the size of the dataset and the nature of the data, individual researchers who routinely implement SP-ICP-MS techniques perform their own data analysis, which usually involves some degree of estimation or other qualitative judgment, thereby introducing inaccuracies and lack of Accuracy and / or reproducibility

Method used

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  • Systems and methods for automated analysis of output in single particle inductively coupled plasma mass spectrometry and similar data sets
  • Systems and methods for automated analysis of output in single particle inductively coupled plasma mass spectrometry and similar data sets
  • Systems and methods for automated analysis of output in single particle inductively coupled plasma mass spectrometry and similar data sets

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Embodiment Construction

[0052] It is intended that the systems, devices, methods and processes of the claimed invention encompass variations and adaptations developed using information from the embodiments described herein. Adaptations and / or modifications of the systems, devices, methods, and processes described herein may be performed by one of ordinary skill in the relevant art.

[0053] In the description, when articles, devices, and systems are described as having, comprising, or including particular components, or when processes and methods are described as having, including, or including particular steps, it is contemplated that there is additionally an essential aspect of the invention. There are apparatuses, devices and systems consisting of or consisting of the recited components and there are processes and methods according to the present invention which essentially consist of or consist of the recited processing steps.

[0054] It should be understood that the order of steps, or order for...

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Abstract

The present disclosure provides methods and systems for automated analysis of spectrometry data corresponding to particles of a sample, such as large data sets obtained during single particle mode analysis of an inductively coupled plasma mass spectrometer (SP-ICP-MS). Techniques are presented herein that provide appropriate smoothing for rapid data processing without an accompanying reduction (or with an acceptably negligible reduction) in accuracy and / or precision.

Description

technical field [0001] The present invention generally relates to the analysis of spectroscopic data. In a particular embodiment, the invention relates to automated peak detection and analysis in single particle inductively coupled plasma mass spectrometry (SP-ICP-MS). Background technique [0002] Inductively coupled plasma mass spectrometry (ICP-MS) has gained favor in laboratories around the world as the instrument of choice for performing trace metal analysis. For many (elements) in the periodic table, ICP-MS instrument detection limits are at or below the individual parts per billion (ppb) level, the analytical working range is nine orders of magnitude, and the productivity Superior to other techniques and easily achievable for isotope analysis. Most analyzes performed on ICP-MS detection instruments are quantitative; however, ICP-MS can equally perform semi-quantitative analysis, allowing, for example, the identification of any one of 80 detectable, distinguishable e...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): H01J49/00H01J49/10G01N15/00
CPCH01J49/0036H01J49/105G01N2015/0038G01N15/10
Inventor S·巴扎尔甘H·巴蒂埃
Owner PERKINELMER HEALTH SCIENCES INC
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