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Cryotherapy system through natural orifice of human body

A natural cavity, cryotherapy technology, applied in cooling surgical instruments, parts of surgical instruments, surgical instruments for suctioning substances, etc., can solve the problems of small freezing range, complicated operation, poor treatment effect, etc. The effect of complete tumor eradication, large treatment range, and complete treatment effect

Inactive Publication Date: 2017-02-22
ACCUTARGET MEDIPHARMA (SHANGHAI) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Existing soft mirror freezing instruments (such as Chinese Patent Publication No. CN102481166) all use carbon dioxide or nitrous oxide as the refrigerant, and its lowest temperature can only reach -40~-80°C, so its freezing range is small, and it is generally only used in clinical practice. For biopsy and foreign body extraction, for lesions with a diameter of more than 1 cm, the operation is complicated and the treatment effect is not good

Method used

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  • Cryotherapy system through natural orifice of human body
  • Cryotherapy system through natural orifice of human body
  • Cryotherapy system through natural orifice of human body

Examples

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Effect test

Embodiment 1

[0029] Examples of different pre-cooling temperatures for different gases are as follows: carbon dioxide can be transformed into a liquid fluid without pre-cooling or pre-cooled at -30~0°C before entering the flexible cold knife 1, and nitrous oxide can be cooled at -50~-20°C ℃ pre-cooling into liquid fluid before entering the flexible cold knife 1, argon can be pre-cooled at -130~-80°C before entering the flexible cold knife 1, nitrogen can be pre-cooled at -110~-140°C before entering the flexible cold knife 1 Cold knife 1, this pre-cooling control method can fully ensure that each gas can reach the state of liquefaction or gas-liquid mixing before or after entering the flexible cold knife 1, thus ensuring sufficient cooling capacity;

[0030]An example of the same gas with different pre-cooling temperatures is as follows: Argon gas is used to enter the flexible cold knife after going through different pre-cooling temperatures as mentioned above. This solution can use a single...

Embodiment 2

[0033] Examples of using independent refrigeration systems to achieve different pre-cooling temperatures are as follows: refrigeration systems I, II, and III can be conventional compression refrigeration systems, self-cascading refrigeration systems, Stirling refrigeration systems, and pulse tube refrigeration systems. Generally speaking, the pre-cooling of 0~-40°C generally uses a conventional compression refrigeration system, which can be used for pre-cooling of carbon dioxide and nitrous oxide. Below -40°C, self-cascading refrigeration systems, Stirling refrigeration systems, and pulse tube refrigeration systems can be selected. Any one of them can be used for pre-cooling of nitrogen and argon.

[0034] An example of using a set of low-temperature refrigeration system to open to different pre-cooling temperatures is as follows: it can be realized by controlling the start-up time of the self-cascade system, the lower the required temperature, the longer the start-up time; it ...

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Abstract

The invention relates to a cryotherapy system through natural orifice of human body, which comprises a flexible cryoprobe, a frozen host, and a gas cylinder, wherein the gas cylinder is connected with the flexible cryoprobe directly or connected with the flexible cryoprobe through the frozen host, making gas of the gas cylinder enter into the frozen host and passing different precooling controls and entering into the flexible cryoprobe lastly. The gas conducts throttling and refrigerating on the internal cutting head of the fore-end of the flexible cryoprobe, thereby getting into the pathological tissue of external cutting head conducting decalescence and freezing the pathological tissue. The cryotherapy system through natural orifice of human body adopts carbon dioxide, nitrous oxide, alkaline air and nitrogen as coolants, wherein alkaline air or nitrogenprecools in the frozen host and then conducts throttling and refrigerating while outputted into the cutting head and gains the temperature below 120o Celsius, which has larger refrigerating range easily, killing the pathological tissue thoroughly. The cryotherapy system through natural orifice of human body provides a new therapeutic scheme for problems of unreachable hard needle puncture and high risk on tumors of cavity.

Description

technical field [0001] The invention relates to a cryomedical device, in particular to a device for cryotherapy of diseased tissue through a natural orifice. Background technique [0002] Lung cancer is one of the most common malignant tumors in the world, and its morbidity and mortality rank first among cancers. 20% of lung cancer patients cannot be surgically resected and have limited benefit from traditional radiotherapy and chemotherapy. As a minimally invasive technique, local ablation has been applied in the treatment of early lung cancer. Cryoablation has gradually matured in the clinical application of malignant tumors. Due to the special anatomical location of the chest, such as tumors close to the mediastinum or scapula, the straight needle cannot be punctured in place for cryotherapy, which creates difficulties for a large number of patients who are suitable for cryoablation. Other cavity tumors such as esophageal cancer, Rectal cancer, nasopharyngeal cancer, pro...

Claims

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Application Information

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IPC IPC(8): A61B18/02
CPCA61B18/02A61B2018/0212A61B2018/0262A61B2218/007
Inventor 孙加源杨迟徐彬凯周飞赵庆孝郑筱轩宋玲
Owner ACCUTARGET MEDIPHARMA (SHANGHAI) CO LTD
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