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Noninvasive and controllable miniature human lumen photodynamic therapy system

A photodynamic therapy and human body technology, applied in the field of medical devices, can solve the problems of normal tissue or organ damage, inaccurate positioning, effective treatment, etc., to increase compliance, avoid bleeding and infection risks, and achieve good therapeutic effects

Inactive Publication Date: 2016-12-21
INST OF BIOMEDICAL ENG CHINESE ACAD OF MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

②The position of the lesion in the entire controllable digestive tract cavity cannot be accurately located. The organ is affected by physiological movement or elastic deformation, which often causes positioning deviation. However, the combination of laparoscopic and optical fiber puncture often cannot directly find the lesion tissue for effective treatment, and sometimes it may even be normal. tissue or organ damage [6]

Method used

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  • Noninvasive and controllable miniature human lumen photodynamic therapy system
  • Noninvasive and controllable miniature human lumen photodynamic therapy system
  • Noninvasive and controllable miniature human lumen photodynamic therapy system

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1 A non-invasive and controllable miniature human body cavity photodynamic therapy system (powered by lithium battery)

[0033] A non-invasive and controllable photodynamic therapy system for miniature human body cavity is composed of LED light source, control magnet, power supply circuit and capsule medical mold shell. Among them, the LED light source is composed of two SMD single-wavelength LEDs with a size of 3mm and a wavelength of 650nm; the control magnet is a cylindrical magnet, which can be driven by an external magnetic field to control the movement of the entire system; the power supply circuit is made of lithium Composed of a battery (button type) and a circuit board, the circuit board plays the role of connecting the LED light source and other working units on the power supply circuit; the capsule-shaped medical mold shell is a capsule-shaped shell with a vacuum interlayer, made of medical transparent epoxy resin , not only can play the role of water...

Embodiment 2

[0035] Example 2 A non-invasive and controllable photodynamic therapy system for miniature human body cavity (wireless power supply)

[0036] A non-invasive and controllable photodynamic therapy system for miniature human body cavity is composed of LED light source, control magnet, power supply circuit and capsule medical mold shell. Among them, the LED light source is composed of two SMD multi-wavelength LEDs with a size of 10mm and wavelengths of 630nm, 650nm, 670nm, and 690nm; the control magnet is four square magnets, which can be driven by an external magnetic field to control the entire system The power supply circuit is composed of LC resonant matching receiving coil, rectifier filter circuit, voltage stabilization module and circuit board. When in use, the external current generating circuit and LC resonant matching transmitting coil are used as the power transmitting unit, and the LC resonant matching receiving coil is used as the power transmitting unit. The power in...

Embodiment 3

[0038] Example 3 A non-invasive and controllable miniature human body cavity photodynamic therapy system (powered by lithium battery)

[0039] A non-invasive and controllable photodynamic therapy system for miniature human body cavity is composed of LED light source, control magnet, power supply circuit and capsule medical mold shell. Among them, the LED light source is composed of two SMD single-wavelength LEDs with a size of 3mm and a wavelength of 532nm; the control magnet is a cylindrical magnet, which can be driven by an external magnetic field to control the movement of the entire system; the power supply circuit is made of lithium Composed of a battery (button type) and a circuit board, the circuit board plays the role of connecting the LED light source and other working units on the power supply circuit; the capsule-shaped medical mold shell is a capsule-shaped shell with a vacuum interlayer, made of polycarbonate, not only It can play the role of waterproof and heat i...

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Abstract

The invention discloses a noninvasive and controllable miniature human lumen photodynamic therapy system, which is characterized by being mainly composed of an LED light source, a control magnet, a power supply circuit and a capsule-type medical mould shell. The LED light source is composed of two patch-type LEDs; the control magnet is one or more small magnet; the power supply circuit includes two modes, namely lithium battery power supply and wireless power supply, wherein in the lithium battery power supply mode, a lithium battery and a circuit board are arranged, and in the wireless power supply module, an LC resonance matching receiving coil, a rectifier and filter circuit, a voltage stabilizing module and a circuit board are arranged; and the capsule-type medical mould shell, which is made from a flexible high-light-transmission waterproof material, is a capsule-type shell provided with a vacuum interlayer. The miniature human lumen photodynamic therapy system disclosed by the invention, as a medical apparatus, has a great potential value in the field of treating gastrointestinal tumors, inflammations, dysbacteriosis and infection; and the photodynamic therapy system is broad in application scope, good in therapeutic effect, safe to use and low in cost.

Description

technical field [0001] The invention belongs to the field of medical devices, and specifically relates to a noninvasive and controllable photodynamic therapy system for miniature human body cavity, in particular to a noninvasive and controllable photodynamic therapy system for miniature human body cavity driven by LED light and external magnetic field and Application of this system in the treatment of human internal cavity diseases. Background technique [0002] Photodynamic therapy (PDT) is one of the most promising new treatments at present. It uses photosensitizers to react with molecular oxygen in biological tissues under the irradiation of light of appropriate wavelengths to generate active singlet oxygen and free radicals. Oxygen components, through oxidation, destroy important cellular components such as proteins, lipids, and nucleic acids, leading to apoptosis or necrosis of diseased cells to achieve therapeutic purposes [1] . PDT has the characteristics of good ti...

Claims

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Application Information

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IPC IPC(8): A61N5/06
CPCA61N5/0603A61N5/062A61N2005/0606A61N2005/0608A61N2005/0609A61N2005/0626A61N2005/0632A61N2005/0651A61N2005/0664
Inventor 刘天军王磊洪阁
Owner INST OF BIOMEDICAL ENG CHINESE ACAD OF MEDICAL SCI
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