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Rare ginsenoside composition including rare ginsenoside Rk3

A kind of technology of ginsenoside and composition, applied in the field of biomedicine

Inactive Publication Date: 2016-12-21
SHAANXI GIANT BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, there is no report on how to combine ginsenosides on the basis of single components to enhance their antitumor effects and prepare highly efficient and low-toxic antitumor drugs.

Method used

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  • Rare ginsenoside composition including rare ginsenoside Rk3
  • Rare ginsenoside composition including rare ginsenoside Rk3
  • Rare ginsenoside composition including rare ginsenoside Rk3

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Example 1 Preparation of Ginsenoside Gum Rk3 Capsules

[0047]Weigh 10kg of ginsenoside Rk3, 0.2kg of oxalic acid, add 68.5kg of starch, mix well, sieve, use ethanol aqueous solution as binder to make a suitable soft material, granulate with 18 mesh sieve, dry in an oven at 60°C for 5 hours, 16 Mesh sieve for granulation, add 500g magnesium stearate, mix well, make capsule.

Embodiment 2

[0048] Example 2 Preparation of Ginsenoside Gum Rk3 Tablet

[0049] Take ginsenoside Rk3 50kg, oxalic acid 1kg, pulverize into fine powder, add microcrystalline cellulose 10kg, sodium carboxymethyl starch 2kg, mix well, wet granulate, dry, add talcum powder 2kg, magnesium stearate 0.3kg, press Tablets were made by conventional tableting preparation process.

Embodiment 3

[0050] Example 3 Preparation of Ginsenoside Gum Rk3 Powder

[0051] Take 40kg of ginsenoside Rk3 and 0.8kg of oxalic acid, grind them into fine powder, add 0.3kg of magnesium stearate, mix evenly, and pack into powders.

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Abstract

The invention provides a rare ginsenoside composition including rare ginsenoside Rk3. The rare ginsenoside composition comprises ginsenoside Rk3 and edible C2-6 organic dicarboxylic acid or tricarboxylic acid, wherein the edible C2-6 organic dicarboxylic acid or tricarboxylic acid accounts for 0.05 to 5 parts by weight on the basis of 100 parts by weight of ginsenoside Rk3. The rare ginsenoside composition has substantial antineoplastic activity and has high efficiency and low toxicity.

Description

technical field [0001] The invention relates to the field of biomedicine, in particular to a rare ginsenoside composition containing rare ginsenoside Rk3, which has anti-tumor activity, high efficiency and low toxicity. Background technique [0002] Cancer is the second most threatening human disease after cerebrovascular disease. The incidence of cancer in my country exceeds 3 million people every year, and the incidence of lung cancer, breast cancer, and esophageal cancer increases year by year, among which the annual growth rate of lung cancer incidence is 26.8%, and the annual growth rate of breast cancer incidence is 6.8%. Over the past 30 years, the mortality rate of breast cancer has increased by 96%, and the mortality rate of lung cancer has soared by 465%. my country's cancer prevention and control work is urgent and the situation is grim. [0003] However, there has not been any report on how to combine ginsenosides on the basis of single components to enhance the...

Claims

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Application Information

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IPC IPC(8): A61K31/704A61P35/00A61K31/194
CPCA61K31/704A61K31/194A61K2300/00
Inventor 段志广范代娣马晓轩刘彦楠李伟娜张婧婧严建亚
Owner SHAANXI GIANT BIOTECHNOLOGY CO LTD
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