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Traditional Chinese medicine capsules for treating intracranial fungal granuloma

A technology of traditional Chinese medicine capsules and granulomas, which is applied in capsule delivery, antifungal agents, and medical raw materials derived from birds. Enhance pharmacological effects and reduce intracranial pressure

Inactive Publication Date: 2016-12-07
秦月霞
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In view of the complex interaction of various active ingredients of various Chinese medicinal materials in the body, changes in the pharmacokinetics and pharmacodynamics of various drugs in the body will have various effects on the interaction between drugs. When used in combination, it may not only produce synergistic drug effects, but also may produce antagonistic effects, which will lead to weakening of drug therapeutic effect or treatment failure. Some drugs in combination will also increase drug toxicity and cause adverse reactions; Enhanced, but when the therapeutic effect is excessively enhanced, it will exceed the body's ability to tolerate it, and it can also cause adverse reactions and even endanger patients.
Part of the research is to prepare traditional Chinese medicine prescriptions in order to treat intracranial fungal granuloma. The most common problem is that the compatibility of the prescriptions is unreasonable, often only from the individual functions and indications of some single or compound medicines and some pharmacodynamic indicators. Instead of copying the theory of Chinese medicine mechanically, the flavor of the prescription can be added or subtracted at will, resulting in an unreasonable composition and contradicting the theory of Chinese medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036]Weighing: 9 grams of light-leaved flower palm wood, 8 grams of crow liver, 8 grams of plantain oil, 7 grams of bay cherry seeds, 6 grams of lampstand leaves, 6 grams of different leaves Patoniae, 5 grams of willow branches, 10 grams of rabbit ears, 18 grams of astragalus, 6 grams of Yingbupu, 5 grams of Anaqi root, 4 grams of medicinal watermelon, 6 grams of calamus, 10 grams of Chuanxiong, 4 grams of goose fat, 12 grams of Himalayan Mirabilis, 6 grams of Dendrobium, 4 grams of plum blossom brain gram, motherwort 5 grams, dandelion 4 grams. The preparation method is as follows: remove impurities from the above-mentioned medicinal materials except plantain oil, mix them, put them in a drying box for drying at 120°C, grind them into 100-130 mesh fines, and mix them with plantain oil evenly. After being sterilized by ultraviolet rays, put it into capsules at a rate of 0.5g / capsule, which is the finished product.

[0037] Dosage: Take orally, 2 times a day, 1 time in the mo...

Embodiment 2

[0054] Weighing: 9 grams of light-leaved flower palm wood, 7 grams of bay cherry seeds, 6 grams of lampstand leaves, 6 grams of different leaves Patoniae, 5 grams of willow branches, 10 grams of rabbit ear grass, 18 grams of astragalus, 6 grams of Yingbupu, 5 grams of anarch root, 4 grams of medicinal watermelon, 6 grams of calamus, 10 grams of Chuanxiong, 4 grams of goose fat, 12 grams of Himalayan mirabilis, 6 grams of Dendrobium dendrobii, 4 grams of plum flower brain, 5 grams of motherwort, and 4 grams of dandelion.

[0055] Among the 10 patients with intracranial fungal granuloma who selected the traditional Chinese medicine capsules made in Example 2 of the present invention, 8 cases were cured and 2 cases were markedly effective. The cure rate is 80%, and the total effective rate is 100%. The cured patients were followed up for 24 months, and no case of recurrence was found. The preparation method is the same as in Example 1.

Embodiment 3

[0057] Weighing: 9 grams of light-leaved palm wood, 7 grams of laurel cherry seeds, 6 grams of lampstand leaves, 6 grams of gall bag flowers, 5 grams of willow branches, 10 grams of rabbit ear grass, 18 grams of astragalus, 6 grams of Yingbupu, A 5 grams of Naqigen, 4 grams of medicinal watermelon, 6 grams of calamus, 10 grams of Chuanxiong, 4 grams of goose fat, 12 grams of Himalayan Mirabilis, 6 grams of Dendrobium dendrobii, 4 grams of Yunnan Pipajia, 4 grams of plum blossom brain, and 5 grams of motherwort , dandelion 4 grams. The preparation method is the same as in Example 1.

[0058] Among the 12 patients with intracranial fungal granuloma who selected the traditional Chinese medicine capsules made in Example 3 of the present invention, 11 cases were cured, and 1 case was markedly effective. The cure rate is 91.6%, and the total effective rate is 100%. The improved and basically cured patients were followed up for 24 months, and no case of recurrence was found.

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PUM

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Abstract

The invention discloses traditional Chinese medicine capsules for treating intracranial fungal granuloma. The traditional Chinese medicine capsules are prepared from the following traditional Chinese medicinal materials in parts by weight: 9 parts of Ormosia nuda fruits, 8 parts of crow livers, 8 parts of juice of Japanese banana, 7 parts of cherry laurel fruits, 6 parts of common alstonia leaves, 6 parts of patrinia heterophylla bunge, 5 parts of willow branches, 10 parts of Shortspike Lagotis, 18 parts of milkvetch roots, 6 parts of roots of Spine Aralia, 5 parts of chrysanthemum cinerariifolium roots, 4 parts of colocynth, 6 parts of acorus calamus, 10 parts of rhizomes of chuanxiong, 4 parts of white-fronted goose fat, 12 parts of Himalayan mirabilis, 6 parts of dendrobium aphyllum, 4 parts of borneol, 5 parts of motherwort herbs and 4 parts of dandelions. Clinical experiments prove that by means of reasonable compatibility of the traditional Chinese medicinal materials, the capsules are good for treating intracranial fungal granuloma, can effectively reduce complications and achieve good efficacy of overall regulation and long-term effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine capsule, in particular to a traditional Chinese medicine capsule for treating intracranial fungal granuloma. Background technique [0002] Intracranial fungal granuloma is an intracranial space-occupying lesion caused by deep fungal infection, which mainly occurs in patients with compromised immune system. Because intracranial fungal granuloma has various etiologies and is prone to complications, it is difficult to take comprehensive care with only a few medicines. It is necessary to properly cooperate with multiple medicines to improve the curative effect or reduce adverse reactions, so as to adapt to the treatment of complex diseases. In view of the complex interaction of various active ingredients of various Chinese medicinal materials in the body, changes in the pharmacokinetics and pharmacodynamics of various drugs in the body will have various effects on the interaction between drugs. When ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61K9/48A61P25/00A61P31/10A61K35/57
CPCA61K36/48A61K9/48A61K35/57A61K36/185A61K36/236A61K36/24A61K36/25A61K36/28A61K36/288A61K36/42A61K36/481A61K36/533A61K36/76A61K36/84A61K36/88A61K36/888A61K36/898A61K36/8984A61K2300/00
Inventor 秦月霞其他发明人请求不公开姓名
Owner 秦月霞
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