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Pharmaceutical composition for treating icteric hepatic diseases, and preparation method and purpose thereof

A composition and drug technology, applied in the field of medicine, can solve the problems of complex composition and high cost

Inactive Publication Date: 2016-12-07
ZHANGZHOU PIEN TZE HUANG PHARM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned composition has disadvantages such as complex composition and high cost, which limit its application.

Method used

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  • Pharmaceutical composition for treating icteric hepatic diseases, and preparation method and purpose thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] The bulk drug of the pharmaceutical composition for the treatment of acute and chronic viral hepatitis in this embodiment consists of:

[0065] 250g capillary, 200g gentian, 100g gardenia, 25g skullcap, 50g licorice, 45g rhubarb, 45g fried white peony, 4g Pien Tze Huang;

[0066] The preparation method of this pharmaceutical composition comprises the following steps:

[0067] Take the selected weight of capillary wormwood, extract it twice with water steam distillation, and obtain the volatile oil and medicinal residue of capillary wormwood respectively;

[0068] Take the gardenia and licorice of the selected weight, add the capillary dregs, take the total weight of the gardenia, licorice, fried white peony root and the capillary dregs as a basis, add water and heat under reflux to extract twice, each time adding Extract 8 times the weight of water for 2 hours, filter, combine the extracts to obtain filtrate A, concentrate the filtrate A to a concentrated solution A wi...

Embodiment 2

[0074] The bulk drug of the pharmaceutical composition for the treatment of acute and chronic viral hepatitis in this embodiment consists of:

[0075] 200g capillary, 240g gentian, 75g gardenia, 30g baicalin, 40g licorice, 54g rhubarb, 36g fried white peony, 7g Pien Tze Huang;

[0076] The preparation method of this pharmaceutical composition comprises the following steps:

[0077] Take the selected weight of capillary wormwood, extract it once with steam distillation, and obtain the volatile oil and medicinal residue of capillary wormwood respectively;

[0078] Take the gardenia and licorice of selected weight, add the capillary dregs, take the total weight of the gardenia, licorice, fried white peony root and the capillary dregs as a basis, add water and heat under reflux for extraction 3 times, adding Extract with 6 times the weight of water for 3 hours, filter, combine the extracts to obtain filtrate A, concentrate the filtrate A to a concentrated solution A with a relati...

Embodiment 3

[0084] The bulk drug of the pharmaceutical composition for the treatment of acute and chronic viral hepatitis in this embodiment consists of:

[0085] Capillary 300g, gentian 160g, gardenia 125g, scutellaria baicalensis 20g, licorice 60g, rhubarb 36g, fried white peony root 54g, Pien Tze Huang 1g;

[0086]The preparation method of this pharmaceutical composition comprises the following steps:

[0087] Take the selected weight of capillary wormwood, extract it with steam distillation 3 times, and obtain the capillary capillary volatile oil and capillary dregs respectively;

[0088] Take a selected weight of gardenia and licorice, add the capillary dregs, based on the total weight of gardenia, licorice, fried white peony root and the capillary dregs, add water and heat under reflux to extract once, each time adding Extract 10 times the weight of water for 1 hour, filter, and combine the extracts to obtain filtrate A, concentrate the filtrate A to a concentrated solution A with ...

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Abstract

The invention relates to a pharmaceutical composition for treating icteric hepatic diseases, and a preparation method and a purpose thereof. The pharmaceutical composition is prepared from the following active pharmaceutical ingredients of 150 to 350 weight parts of herba artemisiae scopariae, 120 to 280 weight parts of radix gentianae, 50 to 150 weight parts of fructus gardeniae, 15 to 35 weight parts of radix scutellariae, 30 to 70 weight parts of liquorice roots, 27 to 63 weight parts of radix et rhizoma rhei, 27 to 63 weight parts of stir-fried radix paeoniae alba and 0.1 to 10 weight parts of Pianzihuang. The channel tropism and the properties of each kind of traditional Chinese medicine are sufficiently considered; the mutual proportioning ratio of all traditional Chinese medicine is selected, so that all of the traditional Chinese medicine is mutually matched in a monarch, minister, assistant and guide matching relationship and are cooperated, so that the effect of treating acute and chronic viral hepatitis is achieved; the pharmaceutical composition only comprises eight kinds of active pharmaceutical ingredients; the composition is simple; the cost is low.

Description

technical field [0001] The invention belongs to the field of medicaments, and in particular relates to a pharmaceutical composition for treating acute and chronic viral hepatitis, a preparation method and application thereof. Background technique [0002] Viral hepatitis is an inflammatory disease of the liver caused by hepatitis A, B, C, D, and E viruses. Clinically, it mainly manifests as fatigue, loss of appetite, nausea, vomiting, hepatomegaly, and liver function damage. Some patients may have jaundice It has the characteristics of strong infectivity, complex transmission routes, wide epidemic range, and high incidence rate. Taking China as an example, about 500,000 to 600,000 new viral hepatitis patients are added each year. All hepatitis viruses can cause acute hepatitis. In addition, hepatitis B, C, and D viruses can also cause chronic hepatitis, which can lead to cirrhosis, liver failure, and liver cancer. [0003] Chinese patent document CN104524054A discloses: a ...

Claims

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Application Information

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IPC IPC(8): A61K36/744A61P1/16A61K35/583A61K35/55A61K35/413
CPCA61K36/744A61K35/413A61K35/55A61K35/583A61K36/258A61K36/282A61K36/484A61K36/515A61K36/539A61K36/65A61K36/708A61K36/71A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 洪绯于娟袁慧君张栋梁
Owner ZHANGZHOU PIEN TZE HUANG PHARM
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