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Pharmaceutical composition with effects of protecting liver and reducing enzymes and preparation method and application thereof

A composition and drug technology, applied in the field of medicine, can solve the problems of complex composition and high cost

Inactive Publication Date: 2016-12-07
ZHANGZHOU PIEN TZE HUANG PHARM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned composition has disadvantages such as complex composition and high cost, which limit its application.

Method used

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  • Pharmaceutical composition with effects of protecting liver and reducing enzymes and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] The bulk drug of the pharmaceutical composition for the treatment of acute and chronic viral hepatitis in this embodiment consists of:

[0065] 250g capillary, 200g gentian, 100g gardenia, 25g skullcap, 50g licorice, 45g rhubarb, 45g fried white peony, 4g Pien Tze Huang;

[0066] The preparation method of this pharmaceutical composition comprises the following steps:

[0067] Take the selected weight of capillary wormwood, extract it twice with water steam distillation, and obtain the volatile oil and medicinal residue of capillary wormwood respectively;

[0068] Take the gardenia, licorice and fried white peony of selected weight, add the capillary dregs, based on the total weight of the gardenia, licorice, fried white peony and the capillary dregs, add water and heat under reflux to extract twice , adding 8 times the weight of water for extraction for 2 hours each time, filtering, combining the extracts to obtain filtrate A, concentrating the filtrate A to a concentr...

Embodiment 2

[0074] The bulk drug of the pharmaceutical composition for the treatment of acute and chronic viral hepatitis in this embodiment consists of:

[0075] 200g capillary, 240g gentian, 75g gardenia, 30g baicalin, 40g licorice, 54g rhubarb, 36g fried white peony, 7g Pien Tze Huang;

[0076] The preparation method of this pharmaceutical composition comprises the following steps:

[0077] Take the selected weight of capillary wormwood, extract it once with steam distillation, and obtain the volatile oil and medicinal residue of capillary wormwood respectively;

[0078] Take a selected weight of gardenia, licorice and fried Radix Paeoniae Alba, add the capillary dregs, take the total weight of the gardenia, licorice, fried white peony root and the capillary root as a basis, add water and heat under reflux to extract 3 times , each time adding 6 times the weight of water for extraction for 3 hours, filtering, combining the extracts to obtain filtrate A, concentrating the filtrate A to...

Embodiment 3

[0084] The bulk drug of the pharmaceutical composition for the treatment of acute and chronic viral hepatitis in this embodiment consists of:

[0085] Capillary 300g, gentian 160g, gardenia 125g, scutellaria baicalensis 20g, licorice 60g, rhubarb 36g, fried white peony root 54g, Pien Tze Huang 1g;

[0086] The preparation method of this pharmaceutical composition comprises the following steps:

[0087]Take the selected weight of capillary wormwood, extract it with steam distillation 3 times, and obtain the capillary capillary volatile oil and capillary dregs respectively;

[0088] Take the selected weight of gardenia, licorice and fried Radix Paeoniae Alba, add the dregs of capillary root, based on the total weight of gardenia, licorice, fried white peony root and the dregs of capillary root, add water and heat under reflux to extract once , each time adding 10 times the weight of water for extraction for 1 h, filtering, combining the extracts to obtain filtrate A, concentrat...

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Abstract

The invention relates to a pharmaceutical composition with the effects of protecting the liver and reducing enzymes and a preparation method and application thereof. The pharmaceutical composition is prepared from 150-350 parts by weight of oriental wormwood, 120-280 parts by weight of radix gentianae, 50-150 parts by weight of fructus gardenia, 15-35 parts by weight of radix scutellariae, 30-70 parts by weight of liquorice roots, 27-63 parts by weight of rhubarb, 27-63 parts by weight of parched white peony roots and 0.1-10 parts by weight of anti-inflammatory and analgesic bolus. The channel tropism and property and flavor of all the traditional Chinese medicine are fully considered, the ratio of the traditional Chinese medicine is selected, the traditional Chinese medicine is matched according to the compatibility relation of adjuvants and messengers and acts jointly, and therefore the function of treating acute and chronic viral hepatitis is achieved; the pharmaceutical composition only comprises the eight bulk drugs, so that the composition is simple, and cost is low.

Description

technical field [0001] The invention belongs to the field of medicaments, and in particular relates to a pharmaceutical composition for treating acute and chronic viral hepatitis, a preparation method and application thereof. Background technique [0002] Viral hepatitis is an inflammatory disease of the liver caused by hepatitis A, B, C, D, and E viruses. Clinically, it mainly manifests as fatigue, loss of appetite, nausea, vomiting, hepatomegaly, and liver function damage. Some patients may have jaundice It has the characteristics of strong infectivity, complex transmission routes, wide epidemic range, and high incidence rate. Taking China as an example, about 500,000 to 600,000 new viral hepatitis patients are added each year. All hepatitis viruses can cause acute hepatitis. In addition, hepatitis B, C, and D viruses can also cause chronic hepatitis, which can lead to cirrhosis, liver failure, and liver cancer. [0003] Chinese patent document CN104524054A discloses: a ...

Claims

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Application Information

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IPC IPC(8): A61K36/744A61P1/16A61P31/12A61K35/583A61K35/55A61K35/413
CPCA61K36/744A61K35/413A61K35/55A61K35/583A61K36/258A61K36/282A61K36/484A61K36/515A61K36/539A61K36/65A61K36/708A61K36/71A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 洪绯于娟袁慧君张栋梁
Owner ZHANGZHOU PIEN TZE HUANG PHARM
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