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Preparation method of toothpaste and mouth wash for preventing and repairing caries

A technology for mouthwash and dental caries, applied in the field of dental restoration, can solve problems such as recurrence, inability to prevent dental caries, etc., and achieve the effects of safe and convenient use, reducing the incidence of caries, and preventing caries

Inactive Publication Date: 2016-12-07
丁玉琴
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention: Aiming at the problem that the current oral material itself is more effective for repairing cavities or tooth defects, but cannot prevent dental caries from reoccurring, the present invention proposes a caries-preventing and caries-repairing toothpaste and mouthwash The preparation method of the present invention, the present invention uses Angelica dahurica, Bai Po, Cyperus Cyperi, Asarum, and Chuanxiong as raw materials to prepare traditional Chinese medicine powder, and use silicon dioxide, dopamine hydrochloride, stevioside, sorbitol, etc. in a vacuum Dental caries prevention and caries restoration toothpaste is prepared in a paste making machine, and sodium bicarbonate, dipotassium hydrogen phosphate trihydrate, calcium chloride, and sodium chloride are used as raw materials, mixed evenly, and then adjusted with trishydroxymethylaminomethane and hydrochloric acid pH, to prepare caries prevention and dental caries mouthwash, the present invention utilizes the method of biomimetic mineralization to adhere to the surface of dentin by oxidative self-polymerization of dopamine, deposits a layer of hydroxyapatite as a bridge, and realizes the remineralization of dentin , forming a firm and dense protective layer, which can effectively prevent caries and repair caries

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0018] Weigh 36g of sodium silicate and 11g of sodium sulfate respectively, add them into 950mL of deionized water, stir at 200r / min for 15min to obtain a mixed solution, raise the temperature of the mixed solution to 80°C, and adjust the pH value of the mixed solution with a mass fraction of 12% sulfuric acid solution 2.5, keep the temperature and keep stirring for 60min, after standing still for 30min, transfer to the centrifuge, centrifuge at 5000r / min, collect the precipitate, wash the precipitate with deionized water until the washing liquid is neutral, put the precipitate in the drying box , dried at 105°C to constant weight, put the dried product into a ball mill, and ball milled at 300r / min for 1 hour to obtain silicon dioxide for toothpaste friction agent; weigh 20g of the dried root of Angelica dahurica and 20g of the dried root of Baishui respectively , 20g dried rhizomes of Cyperus cyperi, 20g dried rhizomes of Asarum, and 20g dried roots of Rhizoma Chuanxiong, put ...

example 2

[0021]Weigh 36.5g of sodium silicate and 11.5g of sodium sulfate respectively, add them into 980mL of deionized water, stir at 250r / min for 18min to obtain a mixed solution, raise the temperature of the mixed solution to 82°C, and adjust the mixed solution with a mass fraction of 12% sulfuric acid solution The pH value is 3.0, keep the temperature and keep stirring for 80min, after standing for 35min, transfer to the centrifuge, centrifuge at 5500r / min, collect the precipitate, wash the precipitate with deionized water until the washing liquid is neutral, put the precipitate in In a drying oven, dry to constant weight at 108°C, put the dried product into a ball mill, and ball mill at 350r / min for 1.5h to obtain silicon dioxide for toothpaste friction agent; weigh 22g of dried roots of Angelica dahurica and 22g of Baizhi Add the dried root tubers, 22g dried rhizomes of Cyperus cyperi, 22g dried rhizomes of Asarum, and 22g dried roots of Ligusticum chuanxiong into a pulverizer, p...

example 3

[0024] Weigh 37g of sodium silicate and 12g of sodium sulfate, add them into 1000mL of deionized water, stir at 300r / min for 20min to obtain a mixed solution, heat the mixed solution to 85°C, and adjust the pH value of the mixed solution with a mass fraction of 12% sulfuric acid solution 3.5, keep the temperature and keep stirring for 90min, after standing still for 40min, transfer to the centrifuge, centrifuge at 6000r / min, collect the precipitate, wash the precipitate with deionized water until the washing liquid is neutral, put the precipitate in the drying box , dried at 110°C to constant weight, put the dried product into a ball mill, and ball milled at 400r / min for 2 hours to obtain silicon dioxide for toothpaste friction agent; weigh 25g of dried root of Angelica dahurica and 25g of dried root of Baishui , 25g dried rhizomes of Cyperus cyperi, 25g dried rhizomes of Asarum, 25g dried roots of Ligusticum chuanxiong, put them into a pulverizer and pulverize them, pass throu...

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PUM

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Abstract

The invention relates to a preparation method of toothpaste and mouth wash for preventing and repairing caries, and belongs to the technical field of tooth repair. The preparation method comprises the steps that traditional Chinese medicine powder is prepared from radix angelicae, radix ampelopsis, rhizoma cyperi, asarum and the rhizome of chuanxiong and mixed with silicon dioxide for toothpaste abrasive, dopamine hydrochloride, stevioside and sorbitol to prepare toothpaste for preventing and repairing caries in a vacuum paste making machine; sodium bicarbonate, trihydrate potassium hydrogen phosphate, calcium chloride and sodium chloride are used as raw materials, tris(hydroxymethyl)methyl aminomethane and hydrochloric acid are used for adjusting pH after the mixture is mixed to be uniform, and mouth wash for preventing and repairing caries is obtained. The toothpaste and the mouth wash adhere to the surface of dentin through dopamine oxidation polymerization by means of a biomimetic mineralization method to be used as a bridge to deposit out a hydroxyapatite layer, dentin remineralization is achieved, a firm and compact protective layer is formed, and caries can be effectively prevented and repaired.

Description

technical field [0001] The invention relates to a preparation method of toothpaste for caries prevention and caries repair and mouthwash, and belongs to the technical field of tooth restoration. Background technique [0002] The population of our country is still in the process of slow growth. Along with the development of the economy, the improvement of people's education level and the emphasis on child rearing, it can be seen that some success has been achieved in the control of dental caries in children. Caries is a potential factor of many serious oral diseases. The earlier it is found, the more effective its control and treatment will be. Therefore, it is necessary to study various common oral pathogenic bacteria that cause caries. While controlling oral pathogenic bacteria, it is also necessary to promote remineralization to repair the damaged glaze as soon as possible for the early caries caused by them, so as to better reduce the harm caused by caries. [0003] Cari...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61K8/41A61K8/24A61Q11/00
CPCA61K8/24A61K8/415A61K8/97A61Q11/00
Inventor 丁玉琴王龙
Owner 丁玉琴
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