Adhering film against oral ulcer and preparation method and application thereof

Abstract

The invention discloses an adhering film against oral ulcer and a preparation method and application thereof. The adhering film comprises, by mass percentage, 0.1-99.8wt% of bioactive glass, 0.1-99.8wt% of adhesive and 0.1-60wt% of water repellent agent. The bioactive glass in the adhering film against oral ulcer has an antibacterial effect and can relieve pain and promote union of the ulcer surface. The adhesive enables the adhering film against oral ulcer to firmly adhere to the ulcer part, the stimulation to the ulcer surface caused by foreign matter is effectively isolated, and thus the pain is relieved. A hydrophobic layer makes the adhering film against oral ulcer not adhere to the surfaces of other mucous membranes such as the gingiva and only adhere to the ulcer surface, the residence time of the adhering film in the oral cavity is remarkably prolonged, the water absorption speed of an adhesive layer can be slowed down, the adhering film against oral ulcer maintains a long time membrane state at the ulcer part, the adhesion time is increased, and the adhering film further has an effect of promoting union.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to an oral ulcer patch and its preparation method and application. Background technique [0002] Oral ulcer is a common disease frequently-occurring disease, is commonly called as " aphthous ulcer ", is a kind of common ulcerative injury disease that occurs in oral mucosa. Oral ulcers can occur at any age and can occur throughout the year. It is characterized by recurrent attacks and unbearable local burning pain, which affects the patient's normal diet and can cause various complications such as bad breath, chronic pharyngitis, headache, and dizziness. Oral ulcer brings great misery to the patient because of having the characteristic of recurrent outbreak. [0003] The etiology of oral ulcers is unknown, and it is the result of a combination of factors, including local trauma, mental stress, food, drugs, malnutrition, changes in hormone levels, and lack of vita...

AI Technical Summary

Problems solved by technology

The protein drug is expensive, requires high storage environment, and is easily inactivated

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