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Preparation method of contact lens care solution

A contact lens and care solution technology, applied in the field of preparation of contact lens care solution, can solve the problems of inflammation and red blood streaks, poor antibacterial moisturizing effect, low oxygen permeability, etc., to achieve the elimination of inflammation and red blood streaks, antibacterial moisturizing Good effect and simple preparation steps

Inactive Publication Date: 2016-11-09
梅庆波
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The technical problem to be solved by the present invention: the current contact lens care solution has toxic and side effects on the human body, and the antibacterial and moisturizing effect is poor, resulting in easy drying of the lens, low oxygen permeability, and dry eyes, discomfort, inflammation, etc. and the problem of red blood streaks, a preparation method of contact lens care solution is provided. The invention first extracts chondroitin sulfate from pig cartilage with sodium hydroxide and sodium chloride, and then carries out water extraction of carrots and chrysanthemums with ultrasonic waves to obtain Mix the extracts, then esterify soybean oil and ethanol under the action of lipase, and then reduce it with hydrogen gas to obtain fatty alcohol, then react with glucose under the action of aldolase to obtain alkyl glucoside, and finally Alkyl glucoside, chondroitin sulfate, mixed extract, etc. are stirred, and then mixed with sodium pyrrolidone carboxylate, etc., to obtain a contact lens care solution

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0018] First, weigh 60g of pig cartilage and crush it with a pulverizer, and add it into a beaker, then add 400mL of 0.5% sodium hydroxide solution and 4g of sodium chloride in sequence, stir and extract for 4 hours, and then add 1% of the mass concentration Adjust the pH to 8.0 with hydrochloric acid, then add 0.05g of trypsin, stir for 3 hours, then place the beaker in a water bath, heat up to 100°C, stir for 20 minutes, then add 3g of activated carbon, stir for 30 minutes, and filter; then add 300mL of Absolute ethanol and 200g of 1% sodium chloride solution were stirred for 30 minutes, filtered to obtain a precipitate, and placed in an oven, dried at 65°C for 3 hours to obtain chondroitin sulfate, which was set aside; then weighed 20g of carrots, Grind 12g of chrysanthemums, put them in a beaker, add 300mL of deionized water, place them in an ultrasonic oscillator, extract them ultrasonically at 200W for 40min, filter to obtain the filtrate, that is, mix the extracts, and s...

example 2

[0021]First, weigh 50g of pig cartilage and crush it with a pulverizer, and add it into a beaker, then add 300mL of 0.5% sodium hydroxide solution and 2g of sodium chloride in sequence, stir and extract for 3 hours, and then add 1% of the mass concentration Adjust the pH to 7.6 with hydrochloric acid, then add 0.03g of trypsin, stir for 2 hours, then place the beaker in a water bath, heat up to 90°C, stir for 10 minutes, then add 1g of activated carbon, stir for 20 minutes, and filter; then add 200mL of Absolute ethanol and 100g of 1% sodium chloride solution were stirred for 20 minutes, filtered to obtain a precipitate, and placed in an oven, dried at 55°C for 2 hours to obtain chondroitin sulfate, which was set aside; then weighed 10g of carrots, Grind 10g of chrysanthemum, put it in a beaker, add 200mL of deionized water, place it in an ultrasonic oscillator, extract it ultrasonically at 180W for 30min, filter to obtain the filtrate, that is, mix the extract, and set aside; ...

example 3

[0024] First, weigh 55g of pig cartilage and pulverize it with a pulverizer, then add it to a beaker, then add 350mL of 0.5% sodium hydroxide solution and 3g of sodium chloride in sequence, stir and extract for 3.5h, and then add 1 % hydrochloric acid to adjust the pH to 7.8, then add 0.04g trypsin, stir and react for 2.5h, then place the beaker in a water bath, heat up to 95°C, stir for 15min, then add 2g of activated carbon, stir for 25min, filter; then add to the filtrate Add 250mL of absolute ethanol and 150g of 1% sodium chloride solution, stir for 25min, filter to obtain a precipitate, put it in an oven, and dry at 60°C for 2.5h to obtain chondroitin sulfate, which is set aside; Grind 15g of carrots and 11g of chrysanthemums, put them in a beaker, add 250mL of deionized water, place them in an ultrasonic oscillator, extract them ultrasonically at 190W for 35min, filter to obtain the filtrate, that is, mix the extracts, and set aside; weigh Add 9g of soybean oil into a fo...

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Abstract

The invention relates to a preparation method of a contact lens care solution and belongs to the technical field of contact lens care solutions. The preparation method comprises the following steps: firstly, extracting chondroitin from pig cartilages by utilizing sodium hydroxide and sodium chloride; then carrying out water extraction on carrots and chrysanthemum flowers by ultrasonic waves to obtain a mixed extracting solution; carrying out esterification on soybean oil and ethanol under the action of lipase; introducing hydrogen gas and reducing to obtain fatty alcohol; taking the fatty alcohol and glucose to react under the action of aldolase to obtain alkyl glucoside; and finally, stirring the alkyl glucoside, the chondroitin, the mixed extracting solution and the like, and adding sodium pyrrolidonecarboxylate and the like and mixing to obtain the contact lens care solution. The contact lens care solution prepared by the invention does not contain substances which have toxic or side effect on human bodies, such as heavy metal; the contact lens care solution has good bacterium-inhibiting and moisture-keeping effects and good cleaning effect; and after contact lenses treated by the contact lens care solution are worn, any discomfort of eyes of a user is not caused, and generated inflammations and red eyes can also be eliminated.

Description

technical field [0001] The invention relates to a preparation method of a contact lens care solution, which belongs to the technical field of contact lens care solutions. Background technique [0002] The main components of contact lens care solution are sodium chloride and preservatives, etc., which are mainly used for cleaning, disinfection, and protein removal of biological materials. It is undoubtedly essential for people who wear contact lenses. Contact lens care solution is used by the contact lens family every day. The deposits and pathogenic bacteria on the surface of the lens must be removed with the care solution first, so that the subsequent sterilization and preservation can be carried out effectively. Because deposits will remain on the surface of the incompletely cleaned lens, when direct sterilization, the bactericidal ingredients will only combine with the sediments, but not with pathogenic bacteria, so the bactericidal ingredients will not be able to play a ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L12/08A61L12/10A61L12/14
CPCA61L12/08A61L12/10A61L12/14
Inventor 梅庆波孟浩影
Owner 梅庆波
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