External traditional Chinese medicine ointment for treating cervical and lumbar diseases and arthritis
An external Chinese ointment, a technology for cervical and lumbar spondylosis, applied in the field of medicine, can solve the problems of ineffective relief of swelling and pain in the affected area, high risk, and high cost
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Embodiment 1
[0015] Weigh 40 grams of raw Nuxyche, 40 grams of raw Nanxing, 40 grams of raw pinellia, 40 grams of raw Chuanwu, 40 grams of raw grass, 8 grams of cinnamon, 8 grams of dried ginger, 8 grams of Angelica dahurica, and 20 grams of Clematis , 8 grams of kaempferia, 8 grams of Chuanxiong, 20 grams of evodia, 20 grams of asarum, 20 grams of ephedra, 40 grams of white mustard seed, 80 grams of Speranthema, 20 grams of angelica, 8 grams of safflower, 8 grams of earth element, and 8 grams of saponins Gram, 8 grams of Dahuo, 8 grams of notopterygium, 40 grams of raw cattail, 8 grams of frankincense, 8 grams of myrrh, 4 grams of camphor, 4 grams of borneol, 0.5 grams of musk and 4 grams of dried blood, crushed, passed through a 100-mesh sieve, Add 200 grams of lanolin and stir evenly to obtain an ointment.
Embodiment 2
[0017] The compound has the following structural formula:
[0018]
[0019] Weigh 1 gram of the compound, add 200 grams of lanolin, and stir evenly to obtain an ointment.
experiment example
[0021] 50 eight-month-old SPF-grade healthy female SD rats, weighing (350±10) g. Type II collagen, complete Freund's adjuvant (produced by Sigma, USA); rat TNF-α enzyme-linked immunoassay kit (produced by R&D Corporation, USA).
[0022] Divided into 10 rats of blank group, 10 rats of model group, 10 rats of embodiment 1 ointment group, 10 rats of embodiment 2 ointment group and 10 rats of control drug methotrexate group. Dissolve type II collagen in 0.1mol / L acetic acid to make a solution with a concentration of 2mg / mL, and store it overnight at 4°C. The next day, it was mixed with complete Freund's adjuvant at a volume of 1:1 to make an emulsion. Use a syringe to pump repeatedly until the mixture is completely and fully emulsified, and the emulsified product will not loosen when it is dripped into the water, and it will float in the water in a drop shape and the emulsification is complete. Take the emulsified collagen-induced rheumatoid arthritis model (CIA) modeling agent,...
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