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Traditional Chinese medicine composition for inhibiting and removing platelet antibody and curing idiopathic thrombocytopenic purpura

A platelet and primary technology, applied in the direction of drug combination, blood disease, medical formula, etc., to achieve long-lasting effects, good curative effect, and improved quality of life

Inactive Publication Date: 2016-11-09
SHANDONG PROVINCIAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But there is no relevant literature at present to report the traditional Chinese medicine composition of the present invention for the treatment of thrombocytopenic purpura

Method used

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  • Traditional Chinese medicine composition for inhibiting and removing platelet antibody and curing idiopathic thrombocytopenic purpura
  • Traditional Chinese medicine composition for inhibiting and removing platelet antibody and curing idiopathic thrombocytopenic purpura
  • Traditional Chinese medicine composition for inhibiting and removing platelet antibody and curing idiopathic thrombocytopenic purpura

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0113] Example 1. A Chinese medicinal composition for inhibiting and eliminating platelet antibodies and treating primary thrombocytopenic purpura, comprising raw materials of the following components: honeysuckle 45g, raw rehmannia 15g, peony 15g, red peony 15g, chuanxiong 15g, Parsnip 12g, comfrey 15g, madder 15g, lotus root charcoal 25g, notoginseng powder 5g, licorice 8g.

[0114] Preparation method: Weigh the medicinal materials according to the amount, soak them in water for half an hour, boil on high fire, then simmer for 40 minutes, take the head and fry, add water and cook for 30 minutes, take two decoctions, decoct them and mix evenly, divide morning and evening Times taken.

Embodiment 2

[0115] Example 2. A Chinese medicinal composition for inhibiting and eliminating platelet antibodies and treating primary thrombocytopenic purpura, including raw materials of the following components: 30g honeysuckle, 10g of rehmannia, 10g of peony root, 10g of red peony root, 10g of chuanxiong, Parsnip 10g, comfrey 10g, madder 10g, lotus root charcoal 20g, notoginseng powder 3g, licorice 6g.

[0116] Preparation method: After weighing the above-mentioned medicines by weight, add deionized water to soak for 30 minutes, decoct twice for the first 45 minutes, filter, and retain the filtrate. Add 4-5 times the amount of medicinal residues to decocting for 30 minutes. After filtering, combine the filtrate and concentrate to 1:1. Add 95% ethanol, stir while adding to make the alcohol content reach 70%, and let stand for precipitation. Take the supernatant, heat and concentrate to prepare the extract. Add appropriate amount of sucrose and dextrin, mix well, add appropriate amount of ...

Embodiment 3

[0117] Example 3. A Chinese medicinal composition for inhibiting and eliminating platelet antibodies and treating primary thrombocytopenic purpura, comprising raw materials of the following components: honeysuckle 60g, raw rehmannia 20g, peonies 20g, red peony 20g, chuanxiong 20g, 15g of windbreak, 20g of comfrey, 20g of madder, 30g of lotus root charcoal, 6g of panax notoginseng powder, 10g of licorice.

[0118] Preparation method: After weighing the above-mentioned medicines by weight, add deionized water to soak for 30 minutes, decoct twice for the first 45 minutes, filter, and retain the filtrate. Add 4-5 times the amount of water to the dregs and decoct for 30 minutes. After filtering, combine the filtrate and concentrate to 1:1. After cooling, add 1.5 times the amount of ethanol, mix well, let it stand overnight, take the supernatant, and use a small amount of the precipitate Wash with 95% ethanol, combine the lotion with the filtrate, recover the ethanol under reduced pres...

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Abstract

The invention provides a traditional Chinese medicine composition for inhibiting and removing aplatelet antibody and curing idiopathic thrombocytopenic purpura, wherein honeysuckle capable of clearing away heat and toxic materials and good at removing blood poisonis is taken as a monarch drug in a prescription, and is used to remove the platelet antibody in the blood. Radix rehmanniae, cortex moutan, red peony root and ligusticum wallichii are taken as an adjuvant drug, and are used to cool blood, clear heat, improve the internal environment of blood heat of a human body, and prevent and control the internal base for the generation of a blood platelet; lithospermum, madder, nodus nelumbinis rhizomatis charcoal and radix notoginseng powder are used to cool blood, remove blood stasis, stop bleeding and improve the signs and symptoms of bleeding; divaricate saposhnikovia root is used to dispel wind and clear heat, and is compatible with the honeysuckle to avoid relapse of the disease, caused by the reason that wind heat enters the interior. Liquorice is a conductant drug, relaxes tension, detoxifies, and coordinates the drug actions of the prescription. The various medicines in the prescription are combined, the prescription is simple but complete, is in great accuracy and hits the pathogenesis, and the various medicines play the roles of detoxifying, cooling blood, dispersing blood stasis, removing ecchymosis and nourishing spleen and kidney together, so that the bleeding of an ITP patient is reduced, and the various clinical symptoms are further alleviated.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine composition for inhibiting and eliminating platelet antibodies and treating primary thrombocytopenic purpura, belonging to the field of traditional Chinese medicine. Background technique [0002] Idiopathic thrombocytopenic purpura or idiopathic thrombocytopenic purpura (Idiopathicthrombocytopenic purpura, ITP) refers to thrombocytopenia caused by no obvious exogenous etiology, but most of them are due to increased platelet destruction caused by immune response, so it is also called Autoimmune thrombocytopenia is a relatively common type of hemorrhagic blood disease. It is characterized by shortened platelet lifespan, increased bone marrow megakaryocytes, 80%-90% of cases have IgG antibodies on the surface of serum or platelets, and no obvious spleen enlargement. [0003] According to the pathogenesis, predisposing factors and course of the disease, ITP is divided into acute type and chronic type. 80% o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61K36/8964A61K36/8969A61P7/04A61P7/00A61K33/06
CPCA61K36/355A61K9/0095A61K33/06A61K36/185A61K36/236A61K36/238A61K36/258A61K36/284A61K36/30A61K36/40A61K36/481A61K36/484A61K36/62A61K36/65A61K36/71A61K36/74A61K36/756A61K36/77A61K36/804A61K36/815A61K36/8964A61K36/8969A61K2300/00
Inventor 王志学杨晶
Owner SHANDONG PROVINCIAL HOSPITAL
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