Production technology of moisture-proof anti-inflammatory drug

Abstract

A formula of a moisture-proof anti-inflammatory drug comprises medicines in parts by weight as follows: 1,950 parts of metronidazole, 1,650 parts of clotrimazole, 82 parts of chlorhexidine acetate, 800 parts of lactose, 980 parts of tartaric acid, 260 parts of low-substituted carboxy cellulose, 750 parts of boric acid, 200 parts of polyvinylpyrrolidone, 260 parts of sodium carboxymethyl starch, 1,000 parts of sodium bicarbonate, 650 parts of pregelatinized starch and 260 parts of microcrystalline cellulose. A technology of the drug comprises the steps of S1, preparing an effervescent film agent solution; S2, preparing a dispersing agent; S3, preparing alkaline particles; S4, preparing acidic particles; S5, preparing main drug particles; S6, preparing a finished product. Moisture in a preparation process can be removed effectively, the drug quality cannot be affected by inside imbibition, meanwhile, outside moisture can be separated from inside effective ingredients and dispersing agent ingredients effectively through a protective film coating outside, the purpose of moisture-proof is achieved, and the technology has very high practical value.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a manufacturing process of moisture-proof and anti-inflammatory medicine. Background technique [0002] With the development of modern medicine, the shape of medicines is constantly changing. The medicines used in traditional Chinese medicine need to be boiled. Modern medicines are mainly administered in pills, tablets and injections. Special, not suitable for injection or oral liquid, and the use of tablets or pills will greatly prolong the time for such drugs to be absorbed by the body, so it is necessary to take the drug in the form of effervescent tablets, but effervescent tablets have higher requirements for moisture resistance. High, mainly because effervescent tablets are easy to foam when exposed to water, and the inside of effervescent tablets is easy to absorb moisture and reduce the quality of finished tablets. The effervescent anti-inflammatory tablet and its corres...

AI Technical Summary

Problems solved by technology

[0002] With the development of modern medicine, the shape of medicines is constantly changing. The medicines used in traditional Chinese medicine need to be boiled. Modern medicines are mainly administered in pills, tablets and injections. Special, not suitable for injection or oral liquid, and the use of tablets or pills will greatly prolong the time for such drugs to be absorbed by the body, so it is necessary to take the drug in the form of effervescent tablets, but effervescent tablets have higher requirements for moisture resistance. High, mainly because effervescent tablets are easy to foam when exposed to water, and the inside of effervescent tablets is easy to absorb moisture and reduce the quality of finished tablets. Effervescent anti-inflammatory tablets and their corresponding production process can solve such problems, so we provide a manufacturing process of moisture-proof anti-inflammatory medicine