Effective part composition containing corn stigma extract and preparation method and application of effective part composition
The technology of corn silk extract and effective part is applied to the effective part composition containing corn silk extract and the field of preparation and application thereof, which can solve the problems of long-term medication, large side effects, curing the symptoms but not the root cause, etc. Easy operation and good taste
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Embodiment 1
[0023] (1) Preparation of corn silk extract: 1kg of corn silk was dried in an oven at 50°C to constant weight; at the same time, a compound enzyme was prepared according to the mass ratio of pectinase, cellulase and hemicellulase at 1:1:1, Then prepare the compound enzyme with water into an enzyme solution with a mass percentage of 0.4%, and adjust the pH of the enzyme solution to 3.0; mix the dried corn silk with the compound enzymatic solution at a mass ratio of 1:1, and enzymolyze at 30°C 30min; After enzymolysis, filter the corn silk-compound enzyme mixture, take the filter residue, add 30% ethanol solution, the ratio of solid to liquid between the filter residue and ethanol solution is 1:10, the temperature is 60°C, and the power extraction is 800W for ultrasonic extraction for 15 minutes , filtered, and the filtrate was taken, and the ethanol was removed by rotary evaporation at 50° C., and vacuum freeze-dried to obtain 125 g of corn silk extract.
[0024] (2) Preparatio...
Embodiment 2
[0031] (1) Preparation of corn silk extract: 1kg of corn silk was dried in an oven at 50°C to constant weight; at the same time, a compound enzyme was prepared according to the mass ratio of pectinase, cellulase and hemicellulase at 3:1:1, Then prepare the compound enzyme with water into an enzyme solution with a mass percentage of 0.1%, and adjust the pH of the enzyme solution to 5.0; mix the dried corn silk with the compound enzymatic solution at a mass ratio of 1:6, and enzymolyze at 60°C 10min; after the enzymolysis, the corn silk-compound enzyme mixture was filtered, the filter residue was taken, and 50% ethanol solution was added, the ratio of solid to liquid between the filter residue and ethanol solution was 1:20, the temperature was 25°C, and the power was 300W, and ultrasonic extraction was performed for 60 minutes. Filtrate, take the filtrate, remove ethanol by rotary evaporation at 50° C., and carry out vacuum freeze-drying to obtain 130 g of corn silk extract.
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experiment example 1
[0038] Experimental example 1 decompression experiment
[0039] The clinical observation patients were divided into 600 cases. All patients had obvious clinical symptoms of hypertension and were diagnosed by clinicians.
[0040] Patient is divided into 3 groups, and group A is the compressed candy of oral embodiment 1 gained, every day 3 times, each 2. Medication time is 15 days. Group B took the tableted candy prepared in Example 2 orally, 3 times a day, 2 tablets each time. Group C was the blank control.
[0041] After 15 days, the statistical results of the patient's blood pressure data can be seen in surface 2 .
[0042]Efficacy criteria: markedly effective includes two situations: the first is that the diastolic blood pressure has dropped by more than 1.3KPa (10mmHg) and reached the normal range; although the diastolic blood pressure has not dropped to normal, it has dropped by more than 2.6KPa (20mmHg). The second type is diastolic blood pressure decreased by less ...
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