Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Medicine for resisting diabetes mellitus

An anti-diabetes and diabetes technology, applied in drug combinations, metabolic diseases, pharmaceutical formulations, etc., can solve problems such as low acceptance

Inactive Publication Date: 2016-08-24
GUANGXI MEDICAL UNIVERSITY
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many varieties of Chinese patent medicines for hypoglycemic drugs. Although doctors are not very accepting of Chinese patent medicines for hypoglycemic drugs, Chinese medicine hypoglycemic drugs have created a market size of hundreds of millions of yuan

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Medicine for resisting diabetes mellitus
  • Medicine for resisting diabetes mellitus
  • Medicine for resisting diabetes mellitus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0005] Describe content of the present invention in detail below in conjunction with embodiment:

[0006] The preparation of the total extract of sour carambola fruit: take 2 kg of carambola fruit, wash them, cut them into small pieces, put them into a juice extractor to crush and squeeze the juice, filter through gauze to remove residue, and concentrate the obtained carambola juice into 5 g of crude drug / ml in a rotary evaporator .

[0007] Application: Suitable for streptozotocin-induced diabetes models.

[0008] Effects of Sour Carambola Fruit Extract on Streptozotocin-induced Diabetic Mice

[0009] Take 90 male Kunming mice, SPF grade, body weight (20±2) g, fast for 12 hours before modeling, 10 are randomly selected as the normal control group, and the remaining mice are intravenously injected with streptozotocin (STZ) 120mg / kg. After 72 hours, blood was collected to measure FBG, and any FBG ≥ 11.1mmol.L-1 was regarded as a diabetic animal model. The successfully mode...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

star fruit, which is also called carambola fruit, belongs to oxalidaceae plants. On the basis of a great amount of pharmacodynamics studies on sour carambola fruits for a long term, a total extract of the sour carambola fruits, upon studies, is proved to be significant in therapeutic effect on mice with streptozotocin-induced diabetes mellitus, and the total extract is capable of obviously reducing a blood glucose level, increasing a serum insulin concentration, improving a renal function, improving glucose tolerance, increasing hepatic glycogen content and SOD (superoxide dismutase) activity in liver tissues and reducing MDA (methane dicarboxylic aldehyde) activity in the liver tissues. The invention can provide a novel medicine for resisting diabetes mellitus to patients with the diabetes mellitus.

Description

technical field [0001] The invention relates to an anti-diabetic drug, in particular to an anti-diabetic drug made of Chinese herbal medicine. Background technique [0002] Diabetes Mellitus (DM) is a chronic disease characterized by energy substance metabolism, especially glucose and fat metabolism disorders. It is a series of metabolic disorder syndromes caused by the interaction of genetic and environmental factors leading to absolute or considerable insulin deficiency and decreased sensitivity of cells to insulin. Eye, kidney, nerve, and cardiovascular complications caused by diabetes are important causes of death and disability in clinical patients, and seriously affect human health, quality of life, and longevity. There are many varieties of Chinese patent medicines for hypoglycemic drugs. Although doctors currently do not accept Chinese patent medicines for hypoglycemic drugs, Chinese medicines for hypoglycemic drugs have created a market size of hundreds of millions...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/185A61P3/10
Inventor 黄仁彬徐小惠张士军韦锦斌林兴杨映霞范氏泰和温庆伟黄婉苏谢秋巧
Owner GUANGXI MEDICAL UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com