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Application of deer-horn glue particles in preparing drug for treating perimenopausal syndrome

A technology of antler gum and granules, applied in the field of medicine, can solve the problems of unsatisfactory use and curative effect, and achieve the effects of abundant raw materials, improved uterine index and simple preparation method.

Inactive Publication Date: 2016-08-10
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] Although there are multiple drugs for the treatment of perimenopausal syndrome, their use and curative effect are not satisfactory due to various reasons. Therefore, it is imperative to develop new drugs for the treatment of perimenopausal syndrome.

Method used

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  • Application of deer-horn glue particles in preparing drug for treating perimenopausal syndrome
  • Application of deer-horn glue particles in preparing drug for treating perimenopausal syndrome
  • Application of deer-horn glue particles in preparing drug for treating perimenopausal syndrome

Examples

Experimental program
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Effect test

Embodiment 1

[0018] In the specific implementation of the present invention, the deer horn glue particles are made of 20g of deer horn glue, 10g of earth-fried yam, and 10g of jujube. water, decocted for 40 minutes, filtered to obtain the first filtrate, added water 6 times the weight of jujube to the dregs, decocted for 30 minutes, filtered to obtain the second filtrate, combined the two filtrates, and concentrated to an amount equivalent to Crude drug 2g / ml, get jujube water decoction concentrate; decoct the deer antler glue, dissolve in the jujube water decoction concentrate to get the mixed liquid; into the mixed solution, dried under reduced pressure, crushed into a fine powder passing through a 100-mesh sieve, mixed with ethanol with a mass concentration of 90% to granulate, and dried to obtain staghorn glue particles.

Embodiment 2

[0020] In the specific implementation of the present invention, the described deer horn gum particles are made of 19g of deer horn gum, 10.5 g of earth-fried Chinese yam, and 9.5 g of jujube, and the preparation method is the same as in Example 1.

Embodiment 3

[0022] In the specific implementation of the present invention, the deer horn gum particles are made of 21g of deer horn gum, 9.5 g of earth-fried Chinese yam, and 10.5 g of jujube. The preparation method is the same as in Example 1.

[0023] Among the above-mentioned medicines, the antler glue warms and invigorates the liver and kidneys, nourishes the essence and nourishes the blood, and is used for dizziness due to blood deficiency, soreness and coldness of the waist and knees, asthenia and emaciation.

[0024] Chinese yam is Huai yam, which has the effects of nourishing and strengthening, helping digestion, suppressing sweating, and stopping diarrhea. It is mainly used for chronic enteritis caused by spleen deficiency, diarrhea, lung deficiency cough, diabetes and thirst, short and frequent urination, nocturnal emission, women's leukorrhagia and indigestion.

[0025] Jujube is warm in nature and sweet in taste. It has the effects of nourishing qi and blood, invigorating the ...

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Abstract

The invention relates to application of deer-horn glue particles in preparing a drug for treating perimenopausal syndrome, and the drug use problem in treating the perimenopausal syndrome can be effectively solved. A method is that the deer-horn glue particles are prepared from 18-22g of deer-horn glue, 9-11g of Chinese yam fried with earth and 9-11g of jujubes, wherein water with the weight being 6-8 times the weight of the jujubes is added into the jujubes each time for decoction, decoction is performed twice, 30-40 minutes every time; two decoction solutions obtained by twice decoction are combined, and the mixture is concentrated until the concentration of a crude drug is 2g / ml, so that water-decocted jujube concentrated liquor is obtained; the deer-horn glue is molten by heat and is dissolved into the water-decocted jujube concentrated liquor to obtain mixed liquor; the Chinese yam fried with the earth is crushed into fine powder which passes through a 100-mesh sieve, the fine powder is dissolved into the mixed liquor to obtain a mixture, the mixture is dried under reduced pressure, the dried mixture is crushed into fine powder which passes through the 100-mesh sieve, and the fine powder is uniformly pelletized by use of alcohol with mass concentration being 90%, and is dried. According to the application, the deer-horn glue particles are rich in raw materials, simple in preparation method, have the effect of remarkably increasing the uterus index, change the states of endometrium, glands and muscular layers, and can be effectively used for preparing the drug for treating the perimenopausal syndrome.

Description

technical field [0001] The invention relates to medicine, in particular to the application of deer horn glue granules in the preparation of medicines for treating perimenopausal syndrome. Background technique [0002] The fundamental cause of perimenopausal syndrome is ovarian failure caused by physiology or pathology or surgery. Once the ovarian function fails or is removed and destroyed, the estrogen secreted by the ovary will decrease. There are more than 400 estrogen receptors in the female body, which are distributed in almost all the tissues and organs of the female body. They are controlled and dominated by estrogen. Once the estrogen decreases, it will cause degenerative changes in organs and tissues, and a series of symptom. [0003] The most typical symptom in perimenopausal syndrome is hot flashes, flushing. It mostly occurs at the age of 45 to 55. Most women may experience symptoms ranging from severity to severity. Some people have symptoms during the menopau...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61K9/16A61P15/00A61K35/32
CPCA61K35/32A61K9/1617A61K36/725A61K36/8945A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 苗明三辛卫云佐艇
Owner HENAN UNIV OF CHINESE MEDICINE
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