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Preparation method of medical biological dressing for haemorrhoids

A technology for biological dressings and hemorrhoids, applied in the field of new medical biological materials, can solve the problems of short washing time, little curative effect, and large irritation, and achieve the effects of long duration of action, no toxic side effects, and less recurrence

Inactive Publication Date: 2016-07-20
SUZHOU BEC BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the treatment methods for hemorrhoids include surgical therapy, internal drug therapy and external drug therapy. The surgical therapy brings great pain to the patient and is prone to complications after the disease, while the curative effect of the internal drug therapy is slow, and the dosage forms used in the external drug therapy are many. It is a lotion, the washing time is usually relatively short, the contact time between the drug and the mucous membrane is very small, and the drug cannot be retained, so that the drug cannot fully play its role, and the curative effect is small, and the irritation is large. Many people even want to treat hemorrhoids quickly. , using injection therapy, but injection therapy will bring some side effects, and often go to the hospital, causing a lot of inconvenience

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] A preparation method of a medical hemorrhoid biological dressing, the preparation method comprising the following steps: in parts by weight, weighing 33 parts of fibrin glue, 33 parts of chitosan, 8 parts of chitin, 8 parts of alginate, 15 parts of astragalus powder 15 parts of bellflower powder, 17 parts of Chuanxiong powder, 13 parts of angelica powder, 14 parts of wolfberry powder, 8 parts of dipotassium glycyrrhizinate, 12 parts of sodium hyaluronate, 6 parts of emulsifier and 35 parts of water are placed in the reactor and stirred After uniformity, keep the solution temperature at 110°C, and heat for 10 minutes; pour the heated mixture onto the film-making mold, scrape it flat, and after it is fully dried, remove the film to obtain the drug storage layer; finally, the prepared drug storage layer The layer and the base cloth are bonded and compounded by an adhesive, and the bonded composite material is punched by a dense needle-punched microporous machine; the punche...

Embodiment 2

[0019] A preparation method of a medical hemorrhoid biological dressing, the preparation method comprising the following steps: in parts by weight, weighing 30 parts of fibrin glue, 30 parts of chitosan, 5 parts of chitin, 4 parts of alginate, 10 parts of astragalus powder 10 parts of bellflower powder, 14 parts of chuanxiong powder, 10 parts of angelica powder, 11 parts of wolfberry powder, 6 parts of dipotassium glycyrrhizinate, 10 parts of sodium hyaluronate, 3 parts of emulsifier and 30 parts of water are placed in the reactor and stirred After uniformity, keep the solution temperature at 110°C, and heat for 10 minutes; pour the heated mixture onto the film-making mold, scrape it flat, and after it is fully dried, remove the film to obtain the drug storage layer; finally, the prepared drug storage layer The layer and the base cloth are bonded and compounded by an adhesive, and the bonded composite material is punched by a dense needle-punched microporous machine; the punche...

Embodiment 3

[0025] A preparation method of a medical hemorrhoid biological dressing, the preparation method comprising the following steps: in parts by weight, weighing 35 parts of fibrin glue, 35 parts of chitosan, 10 parts of chitin, 12 parts of alginate, 20 parts of astragalus powder 20 parts of bellflower powder, 20 parts of chuanxiong powder, 15 parts of angelica powder, 17 parts of wolfberry powder, 10 parts of dipotassium glycyrrhizinate, 14 parts of sodium hyaluronate, 10 parts of emulsifier and 40 parts of water are placed in the reactor and stirred After uniformity, keep the solution temperature at 110°C, and heat for 10 minutes; pour the heated mixture onto the film-making mold, scrape it flat, and after it is fully dried, remove the film to obtain the drug storage layer; finally, the prepared drug storage layer The layer and the base cloth are bonded and compounded by an adhesive, and the bonded composite material is punched by a dense needle-punched microporous machine; the pu...

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PUM

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Abstract

The invention discloses a preparation method of a medical biological dressing for haemorrhoids. The preparation method comprises the steps as follows: firstly, raw materials are weighed in parts by weight, put in a reactor and evenly mixed, the solution temperature is maintained to be 110 DEG C, and heating is performed for 10 minutes; secondly, the heated mixture is poured into a membrane production mold, strickled flat and fully dried, then demolding is performed, and a medicine storing layer is prepared; thirdly, the prepared medicine storing layer and base fabric are bonded and compounded through a binder, and a dense microporous puncturing machine is used for puncturing the bonded composite; the punctured dense composite is cut into a required shape and sealed for sterilization. The biological dressing prepared with the method adopts a traditional Chinese medicine formula and has small irritation, but has no toxic or side effects; haemorrhoids cannot easily relapse; the biological dressing has the advantages of taking effect rapidly, being absorbed completely, not injuring the mucosa and being clean and sanitary, is good in treatment effect, capable of fully playing the pharmacodynamic effect and long in acting duration, and has quite good treatment effects on bleeding, swelling, pains and the like caused by haemorrhoids.

Description

technical field [0001] The invention belongs to the field of new medical biological materials, and relates to a preparation method of a medical hemorrhoid biological dressing. technical background [0002] In recent years, with the development of society, people are under more and more pressure. They often work overtime, which leads to sitting for too long. Coupled with changes in diet structure and eating habits, high fever, spicy, and oily foods have become a problem for many people. The taste of daily diet and the increase of intra-abdominal pressure caused by obesity significantly increase the incidence of hemorrhoids. In the whole anorectal diseases, the incidence of hemorrhoids accounts for about 87.3%. Hemorrhoids are soft vein masses formed by the flexion and expansion of the venous plexus under the mucous membrane of the end of the human rectum and the skin of the anal canal. Bleeding, itching, pain and prolapse are the four common clinical manifestations of hemorr...

Claims

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Application Information

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IPC IPC(8): A61L15/40A61L15/32A61L15/28A61L15/44A61K36/815A61K9/70A61P9/14A61K31/704
CPCA61L15/32A61K9/7023A61K31/704A61K36/232A61K36/236A61K36/346A61K36/481A61K36/815A61K47/36A61K47/42A61L15/28A61L15/40A61L15/44A61L2300/30A61L2300/418C08L5/08C08L5/04A61K2300/00
Inventor 李苏扬李文遐徐勤霞
Owner SUZHOU BEC BIOLOGICAL TECH
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