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Isolated microorganism strains lactobacillus plantarum mcc1 dsm 23881 and lactobacillus gasseri mcc2 dsm 23882 and their use

A technology of MCC2DSM23882 and Lactobacillus gasseri, applied in the direction of microorganisms, Lactobacillus, microorganisms, etc., can solve problems such as insufficient amount of prostate disease

Active Publication Date: 2016-07-06
诺慧斯生物科技公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] Despite this, there are not enough food products and dietary supplements available on the market to reduce milk allergy and prostatic disease

Method used

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  • Isolated microorganism strains lactobacillus plantarum mcc1 dsm 23881 and lactobacillus gasseri mcc2 dsm 23882 and their use
  • Isolated microorganism strains lactobacillus plantarum mcc1 dsm 23881 and lactobacillus gasseri mcc2 dsm 23882 and their use
  • Isolated microorganism strains lactobacillus plantarum mcc1 dsm 23881 and lactobacillus gasseri mcc2 dsm 23882 and their use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0121] Example 1: Food products and dietary supplements (which have the health properties mentioned above, containing the microorganism Lactobacillus plantarum MCC1 or milk gravidarum) that produce milk allergy response and symptoms of urinary tract irritation and associated reduction in oxidative stress and inflammation Bacillus MCC2 or a combination thereof).

[0122] Preferred embodiments are presented below.

[0123] For the production of food products and / or dietary supplements with reduced milk allergy response and urinary tract disorders, microbial cultures pre-grown in fermenters for 24 hours were used and then lyophilized.

[0124] To produce a food product, freeze-dried microbial cultures of Lactobacillus plantarum MCC1 and / or Lactobacillus gasseri MCC2 are dissolved in a small amount of warm (at least 20°C) whey, milk or from milk powder / milk protein concentrate or other milk protein sources. The prepared solution was activated for at least 4 hours.

[0125] The m...

Embodiment 2

[0151] Example 2: Additives for food products and dietary supplements containing microorganisms Lactobacillus plantarum MCC1 or Lactobacillus gasseri MCC2 or combinations thereof for producing milk allergy response and symptoms of urinary tract irritation and associated reduction in oxidative stress and inflammation

[0152] As product additives, use seabuckthorn fruit juice (BT) (made from seabuckthorn berries, preservative-free, cold-compressed and pasteurized), raspberry-blueberry fruit juice drink concentrate (components: concentrated raspberry-blueberry juice ( RB), sugar, acidity regulator citric acid, preservative potassium sorbate diluted 10 times), lingonberry concentrated juice drink (C) and blueberry concentrate (B) (see Table 10). The antioxidant activity (TAA and DPPH test) and the content of vital elements of the additives were determined by atomic absorption spectrophotometer (AAS) method SpektraAAFS and 220Z. (Varian, Australia), in the air-acetylen mixture, th...

Embodiment 3

[0153] Embodiment 3: Clinical Trial No. 1

[0154] Product safety and beneficial effects, biochemical-clinical and sensory testing.

[0155] Using the pluripotent strains and additives obtained through multiple biological selection, and applying suitable technical solutions (see Example 1), food products FP-I (MCC1+ Lactobacillus gasseri MCC2, BT) and FP-II (MCC1, RB). Clinical trials (approved by the Ethical Review Board of Tartu University according to the Declaration of Helsinki of the World Medical Association) were subsequently performed to elucidate the safety and health effects of the food products FP-I and FP-II.

[0156] The main protocol of the clinical trial was as follows: 25 volunteers (11 females, 14 males), 40-65 years old, were randomly assigned into two groups according to the following study selection criteria: absence of clinical problems, chronic diseases, special diet, vitamin use , mineral preparations, participants did not have to change their physical...

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Abstract

The present invention relates to new microorganism strains L.plantarum MCCl DSM 23881 and L.gasseri MCC2 DSM 23882 and their use as antioxidant proteolytic ingredients for the production of food products and dietary supplements. Food products and dietary supplements containing L.plantarum MCCl and L.gasseri MCC2 are hypoallergenic, reduce milk allergy and lower urinary tract irritation symptoms accompanying benign prostatic hyperplasia and oxidative stress and inflammation associated with these.

Description

[0001] The application date is February 23, 2012, the application number is 201280020352.2, and the invention name is "isolated microbial strain Lactobacillus plantarum (LACTOBACILLUSPLANTARUM) MCC1DSM23881 and Lactobacillus gasseri (LACTOBACILLUSGASSERI) MCC2DSM23882 and its application" divisional application. technical field [0002] The invention belongs to the field of biotechnology and will be used in the food industry. More precisely, the present invention relates to microbial strains Lactobacillus plantarum (L. plantarum) MCC1 and Lactobacillus gasseri (L. gasseri) MCC2 and their role in reducing milk allergy and lower urinary tract irritation symptoms and oxidative stress associated with benign prostatic hyperplasia. Inflammation and inflammation associated therewith. Background technique [0003] Lactobacillus, has been widely used for a long time for the preparation of healthy food products, for example as a starter culture. The most common way is the use of Lac...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12N1/20A23C9/123A23C21/02A23J3/08A23J3/22A23L33/135C12R1/225
CPCA23C9/1234A23C21/026A23J3/08A23J3/22A23C2220/208A23V2002/00C12R2001/225C12N1/205A23V2400/145A23V2200/02A23V2200/30A23V2250/5424A23L33/135A23L2/52A23L2/66C12N1/20A61P13/00A61P13/08A61P37/00A61P37/08C12R2001/25C12N1/00A23V2400/169
Inventor T.库里萨亚尔M.滋梅E.塔姆萨亚尔A.维斯基奥贾E.森吉塞普K.滋梅L.博布罗维斯基K.埃里奇M.雷特塞普M.普纳布M.瓦萨尔M.米科萨亚尔
Owner 诺慧斯生物科技公司
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