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Preparation method of traditional Chinese medicine composition for treating leukopenia after chemotherapy

A leukopenia and composition technology, applied in the direction of drug combination, pharmaceutical formula, extracellular fluid disease, etc., can solve the problems of easy infection, unreliable curative effect, expensive price, etc., to relieve headaches, improve the body's immune function and Effects of disease resistance and prolongation of lifespan

Inactive Publication Date: 2016-06-01
QINGDAO HUAZHICAO PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, the treatment of leukopenia caused by chemotherapy drugs often uses colony-stimulating factor as adjuvant therapy. This type of drug has a significant effect but is relatively expensive
In addition, there are other treatments such as hormone therapy. The disadvantage is that the curative effect is unreliable and it is easy to induce infection; oral administration of vitamins, batyl alcohol, and leucogen, although they have a certain effect of increasing white blood cells, are expensive, easy to repeat, and the curative effect is not good.

Method used

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  • Preparation method of traditional Chinese medicine composition for treating leukopenia after chemotherapy
  • Preparation method of traditional Chinese medicine composition for treating leukopenia after chemotherapy

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Comparison scheme
Effect test

Embodiment 1

[0028] The preparation of embodiment 1 Chinese medicine composition capsule of the present invention

[0029] Weigh respectively: 24 parts of astragalus, 24 parts of Codonopsis pilosula, 3 parts of donkey-hide gelatin, 3 parts of Ganoderma lucidum, 15 parts of cat's claw, 3 parts of lobelia, 6 parts of psoralen, 12 parts of papaya, 12 parts of poria cocos, 6 parts of Gallus gallis , 12 parts of Citrus aurantium;

[0030] Add water 9 times the total weight of the above raw materials and extract twice, 2 hours each time, combine the extracts, concentrate under reduced pressure to obtain a thick paste, dry and pulverize the thick paste, add appropriate amount of auxiliary materials, mix well, put into capsules, so that each capsule contains Crude drug 0.5g.

Embodiment 2

[0031] The preparation of embodiment 2 Chinese medicine composition capsules of the present invention

[0032] Weigh respectively: 20 parts of astragalus, 20 parts of Codonopsis pilosula, 5 parts of donkey-hide gelatin, 4 parts of Ganoderma lucidum, 20 parts of cat's claw, 4 parts of lobelia, 3 parts of psoralen, 8 parts of papaya, 8 parts of poria cocos, 10 parts of gallinacea , 10 parts of Citrus aurantium;

[0033] Add water 9 times the total weight of the above raw materials and extract twice, 2 hours each time, combine the extracts, concentrate under reduced pressure to obtain a thick paste, dry and pulverize the thick paste, add appropriate amount of auxiliary materials, mix well, put into capsules, so that each capsule contains Crude drug 0.5g.

Embodiment 3

[0034] The preparation of embodiment 3 Chinese medicine composition capsules of the present invention

[0035] Weigh respectively: 8 parts of Astragalus, 8 parts of Codonopsis, 1 part of donkey-hide gelatin, 1 part of Ganoderma lucidum, 8 parts of cat's claw, 1 part of lobelia, 3 parts of psoralen, 4 parts of papaya, 4 parts of poria cocos, 4 parts of gallinacea , 4 parts Citrus aurantium;

[0036] Add water 9 times the total weight of the above raw materials and extract twice, 2 hours each time, combine the extracts, concentrate under reduced pressure to obtain a thick paste, dry and pulverize the thick paste, add appropriate amount of auxiliary materials, mix well, put into capsules, so that each capsule contains Crude drug 0.5g.

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Abstract

The invention discloses a preparation method of a traditional Chinese medicine composition for treating leukopenia induced by chemotherapy, belonging to the technical field of traditional Chinese medicines. The preparation method comprises the following steps: respectively weighing astragalus root, dangshen, ass-hide glue, ganoderma lucidum, ternate buttercup root, lobelia chinensis, fructus psoraleae, pawpaw, tuckahoe, endothelium corneum gigeriae galli and immature bitter orange as raw materials according to the traditional Chinese medicine prescription; adding water for extracting; mixing the extracting solutions; carrying out vacuum concentration to obtain thick paste; and drying and crushing the thick paste to obtain the traditional Chinese medicine composition. The traditional Chinese medicine composition prepared by the preparation method disclosed by the invention is obtained by long-term improvement on the basis of the ancestral prescription for strengthening the body resistance to consolidate the constitution, has a leukocyte increasing effect, and not only can improve the immune function and disease resistance of the body but also can reduce the injury to the body induced by chemotherapy, thereby ensuring the successful completion of chemotherapy, greatly increasing the quality of life of patients and prolonging the life time of the patients. The traditional Chinese medicine composition is suitable for clinical application, and the preparation method is simple.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a method for preparing a traditional Chinese medicine composition for treating leukopenia after chemotherapy. Background technique [0002] Chemotherapy and radiotherapy are one of the main methods to treat cancer. Chemotherapy is the abbreviation of chemical drug therapy. Due to the low selectivity of chemotherapy drugs, it will inevitably damage the normal cells of the human body while killing cancer cells, resulting in adverse drug reactions. The most common dose-limiting toxicity is bone marrow suppression, manifested as total white blood cell count, absolute neutrophil count and / or thrombocytopenia, thus affecting the effect of cancer treatment. [0003] Therefore, it is particularly important to protect the hematopoietic function of the bone marrow, increase the number of white blood cells, and reduce the damage of chemotherapy and cancer toxins to th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61P7/00A61K35/36A61K35/57
CPCA61K35/36A61K35/57A61K36/074A61K36/076A61K36/34A61K36/344A61K36/481A61K36/487A61K36/71A61K36/732A61K36/752A61K2236/331A61K2236/39A61K2300/00
Inventor 刘学键
Owner QINGDAO HUAZHICAO PHARMA CO LTD
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