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Preparation method of medicine preparation for treating common cold in children

A technology for children's colds and pharmaceutical preparations, which is applied in the field of preparation of traditional Chinese medicine preparations, can solve the problems of simple and extensive extraction and preparation process, poor compliance of children's medication, and difficulty in meeting medication needs, achieving good extraction and separation effects, short extraction time, and saving Energy and Cost Effects

Inactive Publication Date: 2016-04-06
JIANGXI KINGSTONE UNITE PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine generally uses antibiotics, hormones, and non-steroidal anti-inflammatory drugs. Although the onset of effect is fast, the side effects are relatively large, which seriously affects the physical and mental health of children; The preparation process is relatively simple and extensive, the drug takes effect slowly, the therapeutic effect is not ideal, and the children's drug compliance is poor, so it is difficult to meet the clinical drug needs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Prescription composition: mint 80kg, nepeta panicle 67kg, bitter almond 80kg, burdock fruit 80kg, scutellaria baicalensis 80kg, bellflower 67kg, peucedanum 80kg, angelica dahurica 27kg, gardenia (fried) 40kg, hawthorn (burnt) 27kg, six divine music (burnt). ) 27kg, malt (coke) 27kg, reed root 120kg, honeysuckle 120kg, forsythia 80kg, sucrose 40kg, dextrin 200kg, stevia 1.5kg, a total of 200,000 bags (2.5g / bag).

[0022] The following steps are used to prepare: honeysuckle, forsythia, burdock fruit, mint, nepeta ear, scutellaria baicalensis, gardenia (fried), bitter almond, bellflower, Peucedanum, Angelica dahurica, hawthorn (burnt), Liushenqu (burnt), Fifteen Chinese herbal medicines such as malt (coke) and reed rhizome are crushed into fine powder for later use; the crushed peppermint and nepeta ear fine powder are mixed with supercritical CO 2 Fluid extraction technology, the extraction pressure is 20Mpa, the extraction temperature is 30°C, and the extraction time is ...

Embodiment 2

[0032] Prescription composition: Mint 160kg, Nepeta 134kg, Bitter almond 160kg, Burdock 160kg, Scutellaria baicalensis 160kg, Campanulaceae 134kg, Peucedanum 160kg, Angelica dahurica 54kg, Gardenia (fried) 80kg, Hawthorn (burnt) 54kg, Six Divine Comedy (burnt). ) 54kg, malt (coke) 54kg, reed root 240kg, honeysuckle 240kg, forsythia 160kg, sucrose 60kg, dextrin 350kg, stevia 2.5kg, a total of 400,000 bags (2.5g / bag).

[0033] The following steps are used to prepare: honeysuckle, forsythia, burdock fruit, mint, nepeta ear, scutellaria baicalensis, gardenia (fried), bitter almond, bellflower, Peucedanum, Angelica dahurica, hawthorn (burnt), Liushenqu (burnt), Fifteen Chinese herbal medicines such as malt (coke) and reed rhizome are crushed into fine powder for later use; the crushed peppermint and nepeta ear fine powder are mixed with supercritical CO 2Fluid extraction technology, the extraction pressure is 30Mpa, the extraction temperature is 45°C, and the extraction time is 2h,...

Embodiment 3

[0035] Prescription composition: Mint 320kg, Schizonepetae 268kg, Bitter almond 320kg, Arctium 320kg, Scutellaria baicalensis 320kg, Campanulaceae 268kg, Peucedanum 320kg, Angelica dahurica 108kg, Gardenia (fried) 160kg, Hawthorn (burnt) 108kg, Six Divine Comedy (burnt). ) 108kg, malt (coke) 108kg, reed root 480kg, honeysuckle 480kg, forsythia 320kg, sucrose 110kg, dextrin 500kg, stevia 4kg, a total of 800,000 bags (2.5g / bag).

[0036] The following steps are used to prepare: honeysuckle, forsythia, burdock fruit, mint, nepeta ear, scutellaria baicalensis, gardenia (fried), bitter almond, bellflower, Peucedanum, Angelica dahurica, hawthorn (burnt), Liushenqu (burnt), Fifteen Chinese herbal medicines such as malt (coke) and reed rhizome are crushed into fine powder for later use; the crushed peppermint and nepeta ear fine powder are mixed with supercritical CO 2 Fluid extraction technology, the extraction pressure is 40Mpa, the extraction temperature is 60°C, and the extraction...

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Abstract

The invention relates to a preparation method of a medicine preparation for treating the common cold in children. The granule for treating the common cold in children is prepared from fifteen herbal medicine materials including honeysuckle, phillyrin, fructus arctii, mint, schizonepetaspike, radix scutellariae, cape jasmine (fried), semen armeniacae amarum, radix platycodi, radix peucedani, radix angelicae dahuricae, hawthorn (burnt), medicated leaven (burnt), malt (burnt), rhizoma phragmitis and the like. The preparation is formed through cyclodextrin wrapping, granulating, granule finishing and subpackaging by means of the modern extraction separation technology of supercritical fluid extraction, ultrasonic extraction, micro-aperture filter membrane filtering and the like. The method is good in extraction separation effect, high in extraction efficiency, and capable of saving energy and cost; the wrapper preparation technology is adopted for the product, the volatilization of volatile oil type functional components is avoided, the bad smell of the product is covered, and the product quality and child patient medicine taking compliance are further improved.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine preparation, in particular to a preparation method of a medicinal preparation for treating colds in children. Background technique [0002] Children's cold, that is, acute upper respiratory tract infection in children, refers to the acute infection of the nasopharynx of the upper respiratory tract above the throat. Children's colds are mainly viruses, and there may be mycoplasma or bacterial infections in addition. The onset is the most common in early childhood, mostly manifested as runny nose, sneezing, nasal congestion, coughing, often accompanied by fever, body temperature can be as high as 39°C-40°C, some children may also have convulsions due to fever, or diarrhea, abdominal pain , vomiting and other symptoms. At present, mainly adopt doctor trained in Western medicine and Chinese medicine treatment for the treatment of infantile cold. Western medicine generally us...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8998A61P11/00
CPCA61K36/534A61K9/1652A61K9/2059A61K36/00A61K36/23A61K36/232A61K36/28A61K36/346A61K36/355A61K36/538A61K36/539A61K36/634A61K36/734A61K36/736A61K36/744A61K36/899A61K36/8998A61K2236/331A61K2236/37A61K2236/53A61K2300/00
Inventor 谢棋李旭刘长远刘路加杜平荣
Owner JIANGXI KINGSTONE UNITE PHARMA CO LTD
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