A clean production process for converting sodium camphorsulfonate into camphorsulfonic acid

Abstract

The invention discloses a clear production technology for converting sodium camphorsulfonate into camphorsulfonic acid. The clear production technology comprises the following steps of step one, carrying out ceramic membrane filtration on a feed solution, and obtaining ceramic membrane dialysate; step two, enabling the ceramic membrane dialysate to enter a bipolar membrane electrodialysis system to carry out bipolar membrane electrodialysis, and obtaining a crude camphorsulfonic acid solution; step three, enabling the ceramic membrane dialysate to enter a continuous ion exchange system to carry out continuous ion exchange, and obtaining a camphorsulfonic acid solution; step four, carrying out reverse osmosis concentration on the camphorsulfonic acid solution, and obtaining a camphorsulfonic acid concentrated solution; step 5, obtaining camphorsulfonic acid crystals through crystallizing, centrifugal separation and crystal drying after carrying out mechanical vapor recompression concentration on the camphorsulfonic acid concentrated solution. According to the camphorsulfonic acid crystals produced by adopting the clear production technology disclosed by the invention, the purity can be more than 99.5 percent, and the crystals reach the pharmaceutical-grade camphorsulfonic acid level; meanwhile, a one-step recovery rate of materials can be more than 95 percent, the cycling volume is reduced, and energy consumption is reduced.

Description

technical field [0001] The invention relates to the field of camphorsulfonic acid production, in particular to a production process for converting sodium camphorsulfonate into camphorsulfonic acid. Background technique [0002] Camphor mainly exists in camphor plant camphor wood, zingiberaceae and alpiniae seeds, and is an indispensable raw material for medicine, daily use and national defense industry. According to its source, camphor is mainly divided into two categories: natural and synthetic. Natural camphor is mainly extracted from the essential oils of Lauraceae plants, and generally has dextrorotatory optical activity; synthetic camphor is made from turpentine through major chemical reactions such as isomerization, acetic acid addition esterification, hydrolysis and dehydrogenation, and is racemized. body. [0003] Camphorsulfonic acid is a derivative of camphor and has a chiral counterpart structure. According to its optical properties, it can be divided into left-...

AI Technical Summary

Problems solved by technology

At present, the chemical industry synthesizes camphorsulfonic acid mainly by first synthesizing sodium camphorsulfonate or sodium camphorsulfonate solution, and then carrying out continuous ion exchange by fixed bed to obtain camphorsulfonic acid solution; often there is a long production cycle and relatively low total yield. Low, poor product purity needs further separation and purification, etc.

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