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Medicine composition for treating osteoporosis and preparation method thereof

An osteoporosis and composition technology, applied in the field of pharmaceutical compositions for osteoporosis treatment and preparation thereof, can solve the problems of poor absorption, large side effects, irritation of the esophagus, etc., and achieve obvious improvement of clinical symptoms and effective treatment rate High, good therapeutic effect

Inactive Publication Date: 2016-03-23
QINGDAO YUNTIAN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is a big problem of taking medicine in this kind of medicine, because it absorbs extremely poorly and stimulates the esophagus, so the medicine requirement is quite strict and precise, and the side effects are very large
[0004] Currently, the curative effect of clinically used drugs for the treatment of osteoporosis is not satisfactory, and chemical drugs often cause serious side effects in the course of medication. urgent need

Method used

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  • Medicine composition for treating osteoporosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Embodiment 1 A kind of pharmaceutical composition for the treatment of osteoporosis and preparation method thereof

[0022] A pharmaceutical composition for the treatment of osteoporosis, which is prepared from the following traditional Chinese medicine components with a weight of Kg: 45Kg psoraleae, 5.5Kg Luo Han Guo, 30Kg Coptis chinensis, 25Kg Ligustrum lucidum, 30Kg Radix Polygoni Multiflori, Plantago 85Kg, Acorus calamus 15Kg, Dipsacus 12Kg, Chrysanthemum chinensis 5Kg, Tribulus terrestris 9Kg, Lonicerae vine 10Kg, Ten Great Merit 6Kg, Chuan Yujin 10Kg.

[0023] A preparation method for a pharmaceutical composition for the treatment of osteoporosis, comprising the steps of:

[0024] (1) Soak Coptis chinensis, Radix Polygoni Multiflori, Dipsacus, Tribulus terrestris and Lonicerae vine in water for 1 hour, extract the volatile oil with a volatile oil extractor, then dry it with anhydrous sodium sulfate to obtain the volatile oil, and then use β-cyclodextrin to clathr...

Embodiment 2

[0028] Embodiment 2 A kind of pharmaceutical composition for the treatment of osteoporosis and its preparation method

[0029] A pharmaceutical composition for the treatment of osteoporosis, which is prepared from the following traditional Chinese medicine components in weight Kg: 60Kg psoraleae, 7Kg Luo Han Guo, 40Kg Coptis chinensis, 30Kg Ligustrum lucidum, 35Kg Polygonum multiflorum, 90Kg plantain , Shichangpu 20Kg, Dipsacus 15Kg, Green Fructus 10Kg, Tribulus terrestris 15Kg, Lonicera vine 15Kg, Ten Great Merits 9Kg, Chuan Yujin 15Kg.

[0030] A preparation method for a pharmaceutical composition for the treatment of osteoporosis, comprising the steps of:

[0031] (1) Soak Coptis chinensis, Radix Polygoni Multiflori, Dipsacus, Tribulus terrestris and Lonicerae vine in water for 1 hour, extract the volatile oil with a volatile oil extractor, then dry it with anhydrous sodium sulfate to obtain the volatile oil, and then use β-cyclodextrin to clathrate the prepared Obtain cla...

Embodiment 3

[0035] Embodiment 3 A kind of pharmaceutical composition for the treatment of osteoporosis and its preparation method

[0036] A pharmaceutical composition for the treatment of osteoporosis, which is prepared from the following traditional Chinese medicine components in weight Kg: 52.5Kg psoraleae, 6.5Kg Luo Han Guo, 35Kg Coptis chinensis, 27.5Kg Ligustrum lucidum, 32.5Kg Polygonum multiflorum, Plantain 87.5Kg, Shichangpu 17.5Kg, Dipsacus 13.5Kg, Chrysanthemum chinensis 7.5Kg, Tribulus terrestris 12Kg, Lonicera vine 12.5Kg, ten major contributions 7.5Kg, Sichuan turmeric 12.5Kg.

[0037] A preparation method for a pharmaceutical composition for the treatment of osteoporosis, comprising the steps of:

[0038] (1) Soak Coptis chinensis, Radix Polygoni Multiflori, Dipsacus, Tribulus terrestris and Lonicerae vine in water for 1 hour, extract the volatile oil with a volatile oil extractor, then dry it with anhydrous sodium sulfate to obtain the volatile oil, and then use β-cyclodex...

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Abstract

The invention relates to a medicine composition for treating osteoporosis and a preparation method of the medicine composition. Because an existing therapeutic medicine has a poor effect for treating osteoporosis, the invention provides the medicine composition for treating osteoporosis. The medicine composition is prepared from the following traditional Chinese medicine ingredients in parts by weight: 45 to 60 parts of fructus psoraleae, 5.5 to 7 parts of siraitia grosvenori, 30 to 40 parts of coptis chinensis, 25 to 30 parts of glossy privet fruits, 30 to 35 parts of radix polygonum multiflorum preparata, 85 to 90 parts of plantain herb, 15 to 20 parts of acorus gramineus, 12 to 15 parts of radix dipsaci, 5 to 10 parts of feather cockscomb seeds, 9 to 15 parts of tribulus terrestris, 10 to 15 parts of honeysuckle stems, 6 to 9 parts of mahonia fortunei and 10 to 15 parts of curcuma sichuaensis. The medicine composition for treating osteoporosis, disclosed by the invention, can be used for improving a clinical symptom of a patient who suffers from osteoporosis, so that the medicine composition is suitable for being promoted and used in clinical application.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a pharmaceutical composition for treating osteoporosis and a preparation method thereof. Background technique [0002] Osteoporosis is a systemic skeletal disease characterized by low bone mass and microarchitectural degeneration of bone tissue, accompanied by increased bone fragility and susceptibility to fracture. Secondary osteoporosis can be secondary to other diseases or caused by drugs. Bone strength and integrity depend on a balance between bone resorption by osteoclasts from the hematopoietic tissue and remodeling by osteoblasts from the marrow stroma. With aging or due to diseases, drugs and other reasons, bone resorption exceeds bone formation, bone loss will occur, and secondary osteoporosis will occur. [0003] Most of the current osteoporosis treatment drugs are bone resorption inhibitors, which have definite curative effects. They mainly inhibit bone reso...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P19/10A61K35/64
CPCA61K36/9066A61K9/1652A61K36/185A61K36/21A61K36/29A61K36/355A61K36/42A61K36/487A61K36/638A61K36/68A61K36/704A61K36/718A61K36/73A61K36/888A61K2236/331A61K2236/333A61K2236/39A61K2236/51
Inventor 王传秀
Owner QINGDAO YUNTIAN BIOTECH
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