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Chitosan gel and preparing method thereof

A chitosan gel and chitosan technology are applied in the direction of pharmaceutical formulas, medical preparations with no active ingredients, medical preparations containing active ingredients, etc., which can solve vaginal stenosis, pyometra and even pyometra , atresia and other problems, to achieve the effect of promoting tissue regeneration and repair, safety and side effects, and no side effects

Inactive Publication Date: 2016-03-23
SHANGHAI TAOHONG CHEM TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If the ulcer surface is adhered to the opposite side, the adhesion may be separated during vaginal examination and cause bleeding. Severe adhesion may cause vaginal stenosis or even atresia, and poor drainage of inflammatory secretions may form pyometra or even pyometra. This is the current situation rare

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The preparation method of chitosan gel: adjust the pH of 100g deionized water to 6.0 with 1mol / L dilute hydrochloric acid, add 10g chitosan and 10g methyl glycol chitosan and mix evenly, then add 1g carbomer Sodium, 4g sodium hydroxymethyl cellulose, 8g glycerin mix homogeneously, obtain the chitosan gel of embodiment 1, pack into plastic hose, every adorn 3g chitosan gel.

Embodiment 2

[0025] The preparation method of chitosan gel: adjust the pH of 100g deionized water to 6.0 with 1mol / L dilute hydrochloric acid, add 20g chitosan and mix evenly, then add 1g carbomer, 4g sodium hydroxymethyl cellulose, 8g glycerin mixes homogeneously, obtains the chitosan gel of embodiment 2, packs plastic hose, and every adorns 3g chitosan gel.

Embodiment 3

[0027] The preparation method of chitosan gel: adjust the pH of 100g deionized water to 6.0 with 1mol / L dilute hydrochloric acid, add 20g methyl glycol chitosan and mix evenly, then add 1g carbomer, 4g hydroxymethyl Cellulose sodium, 8g glycerin mix homogeneously, obtain the chitosan gel of embodiment 3, pack into plastic hose, every dress 3g chitosan gel.

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PUM

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Abstract

The invention discloses chitosan gel and a preparing method thereof, wherein the preparation method comprises the following steps: regulating a pH of 98-102 parts of water to 5.3-6.3, adding 15-25 parts of chitosan compound for uniformly mixing, then adding 0.8-1.2 parts of Carbomer, 3-5 parts of carboxymethyl cellulose sodium and 6-9 parts of glycerinum and uniformly mixing to obtain the chitosan gel. The chitosan gel has the function of being antibacterial, and capable of diminishing inflammation, stopping blood, reducing wound exudation and promoting a tissue to regenerate, repair and heal by using good biocompatibility and biodegradability of chitosan, has the advantages of flexibility, water absorption and ventilating in various auxiliaries, can inhibit growth and propagation of germs and achieves the effect of treating and preventing diseases. The chitosan gel is safe without toxic and side effects through use and has no drug resistance.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a chitosan gel and a preparation method thereof. Background technique [0002] Vaginitis can be divided into the following five types: bacterial vaginosis, candida vaginitis, trichomonal vaginitis, senile vaginitis, and young female vaginitis. [0003] Bacterial vaginosis is mainly a type of vaginitis caused by Gardnerella vaginalis, which can be transmitted through sexual relations. Bacterial vaginosis is a disease caused by the increase of Gardnerella and anaerobic bacteria, the decrease of Lactobacillus, and the change of the ecological balance system in the vagina. Among them, healthy women also have Gardnerella parasitism in the vagina. [0004] Mycotic vaginitis or candidal vaginitis is vulvovaginal candidiasis (VVC), which is a common multiple vulvovaginal inflammatory disease caused by Candida. Candida albicans is an opportunistic pathogen. 10-20%...

Claims

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Application Information

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IPC IPC(8): A61K9/06A61K31/722A61K47/38A61K47/32A61P31/04A61P15/00A61P15/02
CPCA61K47/32A61K47/38A61K9/0034A61K9/06A61K31/722A61K2300/00
Inventor 黄毅
Owner SHANGHAI TAOHONG CHEM TECH
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