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Traditional Chinese medicine used for treating bacterial vaginitis

A vaginitis and bacterial technology, which is applied in the field of external-use traditional Chinese medicine compositions for the treatment of bacterial vaginosis, can solve the problems of increased drug resistance of azoles, increased drug toxicity and side effects, and the like, achieves low recurrence rate, relieves pain, and enhances sterilization. efficacy effect

Inactive Publication Date: 2016-03-09
苏赵珍
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, recurrent episodes, long-term medication of patients will increase drug resistance to azole drugs, enhance drug toxicity and side effects, and drug resistance of bacterial strains is also a potential problem. Finding broad-spectrum, high-efficiency, and low-toxic antifungal new drugs has become a hot spot in drug research

Method used

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Examples

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preparation example Construction

[0046] The present invention also provides a preparation method of the above-mentioned Chinese medicine composition. When the dosage form of the Chinese medicine composition is a suppository, the specific steps are:

[0047] The first step is to mix the various raw materials together, add water to decoct twice, add water 10 to 15 times the mass of the mixture for the first time, decoct for 1 to 2 hours, filter, and add the relative Water with 5-8 times the mass of the mixture, decocted for 1-2 hours, filtered, mixed the filtrates obtained from the two filtrations, concentrated to a paste with a relative density of 1.15-1.30 at 60°C, and then added 0.6-1.2 Ethanol with an alcohol concentration twice the paste volume of 70% to 80%, let it stand for 12 to 24 hours, filter, concentrate the filtrate under reduced pressure, dry and pulverize to obtain a fine powder;

[0048] In the second step, polyethylene glycol 6000 and polyethylene glycol 4000 are mixed in a ratio of 5:1 to obta...

Embodiment 1

[0051] The concrete preparation of embodiment 1 lotion 1

[0052] Toosendan 25g, patchouli 25g, toad venom 15g, Tibetan calamus 35g, fennel 30g, bean root 35g, brucea javanica 35g, coptis 60g, Kochia chinensis 45g, zedoary 30g, three white grass 35g, Smilax tuckahoe 25g , 30g mugwort leaves, 40g pulsatilla, 35g cork, 25g golden cherry, 25g gorgon and 40g qinpi, add water to decoct twice, add 6.2kg water for the first time, decoct for 2 hours, filter, and put in the filter residue Add 3.3kg of water again, decoct for 2 hours, filter, mix the filtrates obtained from the two filtrations, concentrate to a paste with a relative density of 1.30 at 60°C, and then add alcohol equal to the volume of the paste with a concentration of 80% ethanol, let it stand for 24 hours, filter, concentrate to a paste with a relative density of 1.30 at 60°C, then add 100g of polysorbate 80 and 80g of sodium benzoate, add water to 500ml, and obtain lotion 1.

Embodiment 2

[0053] The specific preparation of embodiment 2 lotion 2

[0054] Toosendan 20g, patchouli 20g, toad venom 10g, Tibetan calamus 30g, fennel 25g, bean root 30g, Brucea javanica 30g, coptis 55g, Kochia chinensis 40g, zedoary 25g, three white grass 30g, Smilax tuckahoe 20g , 25g Artemisia argyi leaves, 35g Pulsatilla chinensis, 30g Phellodendron chinensis, 20g golden cherry, 20g Gorgon fruit and 35g Qinpi, mix together, add water to decoct twice, add 6.2kg of water for the first time, decoct for 2 hours, filter, and put in the filter residue Add 3.3kg of water again, decoct for 2 hours, filter, mix the filtrates obtained from the two filtrations, concentrate to a paste with a relative density of 1.30 at 60°C, and then add alcohol equal to the volume of the paste with a concentration of 80% The ethanol was left to stand for 24 hours, filtered, concentrated to a paste with a relative density of 1.30 at 60°C, then 100g of polysorbate 80 and 80g of sodium benzoate were added, and the...

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Abstract

The invention provides an external traditional Chinese medicine used for treating bacterial vaginitis. The external traditional Chinese medicine composition comprises the following raw materials: fructus meliae toosendan, pogostemon cablin, venenum bufonis, Acorus calamus L., Rhizoma Dioscoreae Hypoglaucae, rhizoma menispermi, Brucea javanica, Coptis chinensis, fructus kochiae, curcuma zedoary, saururus chinensis, rhizoma smilacis glabrae, folium artemisiae argyi, pulsatilla chinensis regel, cortex phellodendri chinensis, fructus rosae laevigatae, Semen Euryales and Cortex Fraxini. The traditional Chinese medicine has high efficiency, faster onset time, is capable of shortening pruritus vulvae extinction time and leucorrhea normalization time, is capable of rapidly relieving the pain of a patient in a short time, is high in cure rate and low in recurrence rate, and is capable of reducing medical expenses in the aspect of treating the bacterial vaginitis.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to an external Chinese medicine composition for treating bacterial vaginosis. Background technique [0002] Bacterial vaginosis is one of the common vaginal inflammatory reactions, a common disease that occurs in women of childbearing age, 75% of women suffer from it at least once in their life, and 40% to 50% of patients have the experience of recurrence. The disease occurs when the body's immunity is weakened, the pH value of the vagina changes, such as pregnancy, diabetes, long-term estrogen treatment, etc., or the microbial balance is disrupted, such as long-term use of antibiotics. The clinical incidence of this disease is slightly higher than that of trichomonas vaginitis. If it is not taken seriously and active treatment measures are taken, it will be transformed into chronic inflammation. In addition to affecting the normal life and work of the patient, ...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P15/02A61P31/04A61K35/65
Inventor 不公告发明人
Owner 苏赵珍
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