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Medicine for prevention and treatment of postoperative lower extremity deep venous thrombosis

A technology of deep vein thrombosis and medicine, which is applied in the field of medicine for preventing and treating deep vein thrombosis of lower extremity after operation

Inactive Publication Date: 2016-01-27
QINGDAO JINZHI HIGH NEW TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Controversy still exists regarding the potency ratio of various drugs

Method used

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  • Medicine for prevention and treatment of postoperative lower extremity deep venous thrombosis
  • Medicine for prevention and treatment of postoperative lower extremity deep venous thrombosis

Examples

Experimental program
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preparation example Construction

[0052] The present invention also provides the preparation method of above-mentioned drop pill, it comprises:

[0053] The first step is to weigh astragalus, fried Atractylodes macrocephala, Poria cocos, Coptis chinensis, Cortex Phellodendron, Atractylodes atractylodes, honeysuckle, papaya and raw licorice in parts by weight, and mix them together, adding 2 to 4 times the weight of these raw materials each time. water, decocting 1 to 3 times, each time for 1 to 3 hours, filtering, combining the filtrates, concentrating to a thick paste with a relative density of 1.05 to 1.20 at 80°C, adding an alcohol concentration 1 to 3 times the volume of the thick paste 80% ethanol, mix well, let it stand for 12-48 hours to precipitate, take the supernatant, recover the ethanol, put it in an oven for drying at 80°C, cool, pulverize, pass through a 100-150 mesh sieve, and obtain the first powder;

[0054] The second step is to take the dried leech, wash it, soak it in water for 10-15 minute...

Embodiment 1

[0058] Embodiment 1 Dropping pill 1

[0059] Weigh 20g of astragalus, 20g of fried Atractylodes macrocephala, 10g of poria cocos, 10g of coptis, 25g of Phellodendron, 10g of herb, 10g of honeysuckle, 10g of papaya and 10g of raw licorice, mix them together, add 400g of water, decoct 2 times, 2 hours each time, Filtrate, combine the filtrates, concentrate to a thick paste with a relative density of 1.10 at 80°C, add ethanol with an alcohol concentration of 80% relative to the volume of the thick paste, mix well, let stand for 24 hours to precipitate, and take the supernatant, Recover ethanol, dry it in an oven at 80°C, cool it, crush it, and pass it through a 100-mesh sieve to get the first powder. Take 20g of dried leech, wash it, soak it in water for 15 minutes, make it soft, cut it off, and dry it in the sun. Stir-fry with talcum powder until it turns yellow-brown, take it out, sieve off the talcum powder, let it cool, grind it into a fine powder, and pass through a 100-mesh...

Embodiment 2

[0060] Embodiment 2 Dropping pill 2

[0061] Weigh 15g of Astragalus membranaceus, 15g of fried Atractylodes macrocephala, 10g of Poria cocos, 10g of Coptis chinensis, 25g of Cortex Phellodendron, 10g of Atractylodes atractylodes, 10g of honeysuckle, 10g of papaya and 10g of raw licorice, mix them together, add 400g of water, decoct twice, each time for 2 hours, Filtrate, combine the filtrates, concentrate to a thick paste with a relative density of 1.10 at 80°C, add ethanol with an alcohol concentration of 80% relative to the volume of the thick paste, mix well, let stand for 24 hours to precipitate, and take the supernatant, Recover ethanol, dry it in an oven at 80°C, cool, crush, pass through a 100-mesh sieve to obtain the first powder, take 15g of dried leech, wash it, soak it in water for 15 minutes, make it soft, cut it off, and dry it in the sun. Stir-fry with talcum powder until it turns yellow-brown, take it out, sieve off the talcum powder, let it cool, grind it into...

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Abstract

The invention provides a medicine for prevention and treatment of postoperative lower extremity deep venous thrombosis. The medicine is characterized by comprising hirudo, suberect spatholobus stem, Danshen root, radix achyranthis bidentatae, dragon's blood, pseudo-ginseng powder, peach kernel, safflower, prepared rehmannia root, Szechuan lovage rhizome, red peony root, radix angelicae sinensis, radix astragali, roasted rhizoma atractylodis macrocephalae, tuckahoe, pilose asiabell root, coptis root, amur cork tree bark, Chinese atractylodes rhizome, honeysuckle, pawpaw and raw liquorice. Through verification of clinical research and experiment research, the medicine which is a preparation has excellent effects when being used for preventing forming of lower extremity DVT (deep venous thrombosis) after TKA (total knee arthroplasty), and through demonstration, a qi-benefiting blood-activating method is feasible and significant to DVT prevention and treatment, provides theoretical bases and clinical cases for further seeking efficient and safe traditional Chinese medicine therapy and also opens up new vision and develops new ideas for modern application advocating famous prescriptions.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a medicine for preventing and treating postoperative deep vein thrombosis of lower extremities. Background technique [0002] With the rapid development of my country's economy and the continuous improvement of people's living standards, the problem of population aging is becoming increasingly serious, and the incidence of bone and joint diseases is increasing year by year, especially the incidence of knee osteoarthritis (KOA) in the elderly There was a marked increase in the population. Osteoarthritis of the knee can cause pain and disability in middle-aged and older adults, with serious adverse effects on patients' quality of life. Therefore, patients have higher and higher requirements and expectations for improving the quality of life and relieving pain. [0003] Traditional treatment methods can no longer meet the requirements and expectations of patien...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/889A61K36/896A61K9/20A61P9/14A61P7/02A61K35/62
Inventor 不公告发明人
Owner QINGDAO JINZHI HIGH NEW TECH
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