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Medicament for treating postradiotherapy xerostomia of head and neck neoplasm

A technology for head and neck tumors and xerostomia, which is applied in the field of traditional Chinese medicine, can solve the problems of high price, poor curative effect, and difficulty in promotion, and achieve the effects of reducing dry mouth, excellent curative effect, and delaying oral mucosal reactions

Inactive Publication Date: 2015-12-30
阚士锋
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Western medicine used vitamins, hormones and other drugs for treatment in the past, but the curative effect was not good. In recent years, although amifostine can be used before radiotherapy to reduce the occurrence of xerostomia and mucositis, it is difficult to promote because of its high price

Method used

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  • Medicament for treating postradiotherapy xerostomia of head and neck neoplasm
  • Medicament for treating postradiotherapy xerostomia of head and neck neoplasm
  • Medicament for treating postradiotherapy xerostomia of head and neck neoplasm

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Embodiment 1 decoction 1

[0050] Take 15g of Nansha ginseng, 15g of Beisha ginseng, 30g of kudzu root, 20g of Tianhuafen, 15g of rehmannia root, 20g of Prunella vulgaris, 15g of Scrophulariaceae, 10g of lily, 20g of honeysuckle, 15g of Ophiopogon japonicus, 15g of Asparagus radix, 20g of Codonopsis radix, 15g of Polygonatum odoratum, Dendrobium 15g, Salvia miltiorrhiza 20g, Poria cocos 20g, Ligusticum chuanxiong 10g, Schisandra chinensis 5g, Ume 15g, Scutellaria baicalensis 15g, washed, crushed separately, put into a container, add distilled water of 10 times the mass of each raw material, soak for 6 hours , boiled for 4 hours, filtered, and the filter residue was added with 7 times the amount of distilled water relative to the sum of the mass of each raw material drug, boiled for 3 hours, and filtered; finally, the filter residue was added with 6 times the amount of distilled water relative to the sum of the mass of each raw material drug, heated and boiled for 2 hours...

Embodiment 2

[0051] Embodiment 2 decoction 2

[0052] Take 15g of Nansha ginseng, 15g of Beisha ginseng, 20g of kudzu root, 20g of trichosanthum, 15g of rehmannia, 15g of Prunella vulgaris, 15g of scrophulariaceae, 10g of lily, 15g of honeysuckle, 15g of Ophiopogon japonicus, 15g of Asparagus radix, 15g of Codonopsis 15g, 15g of Yuzhu, Dendrobium 15g, Salvia miltiorrhiza 20g, Poria cocos 20g, Ligusticum chuanxiong 10g, Schisandra chinensis 10g, ebony plum 15g, scutellaria baicalensis 1g, washed, crushed separately, put into a container, add distilled water 10 times the mass of each raw material, soak for 6 hours , boiled for 4 hours, filtered, and the filter residue was added with 7 times the amount of distilled water relative to the sum of the mass of each raw material drug, boiled for 3 hours, and filtered; finally, the filter residue was added with 6 times the amount of distilled water relative to the sum of the mass of each raw material drug, heated and boiled for 2 hours , filtered; c...

Embodiment 3

[0053] Embodiment 3 decoction 3

[0054] Take 20g of Nansha ginseng, 20g of Beisha ginseng, 30g of kudzu root, 30g of trichosanthin, 25g of rehmannia, 25g of Prunella vulgaris, 20g of scrophulariaceae, 15g of lily, 20g of honeysuckle, 20g of Ophiopogon japonicus, 20g of asparagus, 20g of Codonopsis radix, 20g of Yuzhu, Dendrobium 20g, Salvia miltiorrhiza 30g, Poria cocos 25g, Chuanxiong 15g, Schisandra chinensis 15g, ebony plum 20g, scutellaria baicalensis 20g, washed, crushed separately, put into a container, add distilled water 10 times the mass of each raw material, soak for 6 hours , boiled for 4 hours, filtered, and the filter residue was added with 7 times the amount of distilled water relative to the sum of the mass of each raw material drug, boiled for 3 hours, and filtered; finally, the filter residue was added with 6 times the amount of distilled water relative to the sum of the mass of each raw material drug, heated and boiled for 2 hours , filtered; combined three ...

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PUM

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Abstract

The invention provides a medicament for treating postradiotherapy xerostomia of head and neck neoplasm. The medicament comprises the following raw medicinal materials: adenophora tetraphylla, radix glehniae, radix puerariae, radices trichosanthis, dried rehmannia root, selfheal, radix scrophulariae, lilium brownie, honeysuckle, ophiopogon root, radix asparagi, codonopsis pilosula, radix polygonati officinalis, dendrobe, salvia miltiorrhiza, poria cocos, ligusticum wallichii, schisandra chinensis, smoked plum and scutellaria baicalensis. The medicament can be used for effectively lightening the xerostomia degree of a patient and delaying the occurrence of an oral mucosa reaction, and has a curative effect superior to that of a western medicine and the advantages of the medicament are sufficiently showed.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a medicine for treating xerostomia after radiotherapy for head and neck tumors. Background technique [0002] Head and neck tumors are clinically more common tumors, accounting for about 5-7% of systemic malignant tumors, ranking sixth. In recent years, the incidence of head and neck tumors in my country has increased significantly, with an annual incidence of 15.22 per 100,000. However, while radiation kills tumors during radiotherapy, it also inevitably damages some normal tissue structures in the head and neck, causing acute and long-term complications and seriously affecting the quality of life of patients. Effective management of complications is important because they may affect patient compliance or cause delays in treatment, leading to ineffective control of tumor growth. Xerostomia is one of the most prominent complications after radiotherapy for h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61P1/02
Inventor 阚士锋陈旭陈红艳
Owner 阚士锋
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