Medicine composition for treating cataract macular oedema

A technology of macular edema and composition, which is applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems of retinal thickness increase, macular edema, affecting vision recovery, etc., and achieve the effect of delaying and preventing the formation and significant curative effect

Inactive Publication Date: 2015-12-23
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The inflammatory reaction increases the permeability of capillaries in the macular area, resulting in the accumulation of extracellular fluid, the increase of retinal thickness in the macular area, and the occurrence of macular edema, which affects the recovery of postoperative vision.

Method used

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  • Medicine composition for treating cataract macular oedema

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Example 1: Pharmaceutical composition for treating cataract macular edema and preparation method thereof

[0034] The composition and parts by weight of the bulk drug of the pharmaceutical composition for the treatment of cataract macular edema are:

[0035] 95 parts by weight of bell bells;

[0036] Preparation:

[0037] (1) According to the ratio of raw materials, take gabionate, ragmosia, bell bell, and rosette, mix well, use 40% ethanol as solvent, and extract by warm soaking at 60°C, and the number of extractions is 5 times , each extraction time is 1 hour, each time the amount of solvent is 15 times the total weight of the above-mentioned medicinal materials, filtered, the extract is recovered from ethanol, concentrated to a relative density of 1.08, filtered, and the medicinal solution passes through the LSA-40 macroporous adsorption resin column , first eluted with water, then eluted the LSA-40 macroporous adsorption resin column with an ethanol solution with ...

Embodiment 2

[0039] Example 2: Pharmaceutical composition for treating cataract macular edema and preparation method thereof

[0040] The composition and parts by weight of the bulk drug of the pharmaceutical composition for the treatment of cataract macular edema are:

[0041] 90 parts by weight of bell bells, 80 parts by weight of galban esters, 50 parts by weight of rags, 50 parts by weight of rosette thistle, 3 parts by weight of swertigin, 3 parts by weight of alisolin B2;

[0042] Preparation:

[0043](1) According to the ratio of raw materials, take gabionate, ragmosia, bell bell, and rosette, mix well, use 40% ethanol as solvent, and extract by warm soaking at 60°C, and the number of extractions is 5 times , each extraction time is 1 hour, each time the amount of solvent is 15 times the total weight of the above-mentioned medicinal materials, filtered, the extract is recovered from ethanol, concentrated to a relative density of 1.08, filtered, and the medicinal solution passes thr...

Embodiment 3

[0045] Example 3: Pharmaceutical composition for treating cataract macular edema and preparation method thereof

[0046] The composition and parts by weight of the bulk drug of the pharmaceutical composition for the treatment of cataract macular edema are:

[0047] 100 parts by weight of bell bell incense, 70 parts by weight of gabion esters, 60 parts by weight of rags, 30 parts by weight of rosette 30 parts by weight, 6 parts by weight of swertinol B1;

[0048] Preparation:

[0049] (1) According to the ratio of raw materials, take gabionate, ragmosia, bell bell, and rosette, mix well, use 40% ethanol as solvent, and extract by warm soaking at 60°C, and the number of extractions is 5 times , each extraction time is 1 hour, each time the amount of solvent is 15 times the total weight of the above-mentioned medicinal materials, filtered, the extract is recovered from ethanol, concentrated to a relative density of 1.08, filtered, and the medicinal solution passes through the LS...

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Abstract

The invention discloses a medicine composition for treating cataract macular oedema. The medicine composition is prepared by taking all-grass of strongfragrant loosestrife, allyl amyl glycolate, cordia berry, herb of rosette thistle, false chinese swertia herb glucoside and rhizoma alismatis terpene alcohol B as crude drugs, and proportioning. The medicine composition can be prepared into various preparations according to a conventional preparation process and has a remarkable effect on treating the cataract macular oedema.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a pharmaceutical composition for treating cataract macular edema. Background technique [0002] Macular edema is a common complication after phacoemulsification (referred to as phacoemulsification), with an incidence rate of 20% to 30%, and the peak period is 6 to 10 weeks after surgery. Patients with diabetes mellitus (DM) have a higher incidence of macular edema after phacoemulsification. Although surgical techniques are becoming more mature, the damage to the blood-aqueous humor barrier during the operation is slight and short-lived, but the damage to the blood-retinal barrier is still inevitable, which can easily lead to leakage of capillaries around the fovea of ​​the macula, resulting in the accumulation of fluid between the retinal layers. Edema occurs. Foreign studies have found that postoperative vision recovery in DM patients is worse than in sim...

Claims

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Application Information

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IPC IPC(8): A61K36/30A61P27/12A61K31/7048A61K31/58
Inventor 张秀华
Owner JINAN XINGYI MEDICAL TECH
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