Traditional Chinese medicine composition for treating coronary heart disease and preparation method of traditional Chinese medicine composition

A composition and coronary heart disease technology, applied in the direction of drug combination, medical formula, cardiovascular system diseases, etc., can solve the problems of unsatisfactory effect of traditional Chinese medicine composition, reduction of toxic and side effects, etc.

Active Publication Date: 2015-12-16
SHAANXI BUCHANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because of this, three invention patents have been applied for the Chinese medicine composition, one of which has a publication number of CN1515296A and its publication date is July 28, 2004, and the other has its publication number of CN101732520A and its publication date is 2010. On June 16, the publication number of the last one was CN1872259A, and the publication date was December 15, 2010. The above-mentioned invention patent documents were disclosed and protected in terms of the dosage of different components in the prescription, the preparation process and the new natural matrix excipients. , but in the actual clinical application process, we found that the effect of the traditional Chinese medicine composition made by the above preparation method is not ideal, and the patent application is to further optimize the prescription dosage ratio and preparation process through a large number of experiments. Experiments have shown that the effect is more significant, and the side effects are also greatly reduced

Method used

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  • Traditional Chinese medicine composition for treating coronary heart disease and preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for treating coronary heart disease and preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for treating coronary heart disease and preparation method of traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0111] (1) Take 44g dried blood and grind it into fine powder;

[0112] (2) Take 111g of Salvia miltiorrhiza, heat and reflux with 8 times the amount of 90% ethanol to extract for 1.5 hours, filter, and recover the ethanol from the filtrate under reduced pressure, add 6 times the amount of water to decoct the dregs for 1 hour, filter, combine the above filtrates, and concentrate under reduced pressure to an appropriate amount , dried under reduced pressure, pulverized into fine powder to obtain Salvia miltiorrhiza extract, set aside;

[0113] (3) Take 44 g of sweetgum, add 6 times the amount of water to extract the volatile oil for 6 hours, and obtain sweetgum oil, set aside;

[0114]⑷Mix the fine powder of dried blood in the above step ⑴, the extract of Salvia miltiorrhiza in step ⑵ and polyethylene glycol 6000, after melting in a water bath, add sweetgum oil in step ⑶, mix well, keep warm, drop into paraffin wax, and make 1000 A drop pill, that is.

Embodiment 2

[0116] (1) Take 35g of dried blood and grind it into fine powder;

[0117] (2) Take 95g of Salvia miltiorrhiza, heat and reflux with 8 times the amount of 90% ethanol to extract for 1.5h, filter, recover the ethanol from the filtrate under reduced pressure, add 6 times the amount of water to decoct the dregs for 1 hour, filter, combine the above filtrates, and concentrate under reduced pressure to Appropriate amount, dried under reduced pressure, pulverized into fine powder to obtain Salvia miltiorrhiza extract, set aside;

[0118] (3) Take 53 g of sweetgum resin, add 6 times the amount of water to extract the volatile oil for 6 hours to obtain sweetgum resin oil, and set aside;

[0119] (4) Add the blood dried blood powder in the above step (1) and the salvia miltiorrhiza extract in the step (2), add maple gum oil in the step (3), mix evenly, mix with appropriate amount of dextrin and sucrose, granulate, and dry to make 1000g granules.

Embodiment 3

[0121] (1) Take 53g of dried blood and grind it into fine powder;

[0122] (2) Take 125g of Salvia miltiorrhiza, heat and reflux with 8 times the amount of 90% ethanol to extract for 1.5h, filter, recover the ethanol from the filtrate under reduced pressure, add 6 times the amount of water to decoct the dregs for 1 hour, filter, combine the above filtrates, and concentrate under reduced pressure to Appropriate amount, dried under reduced pressure, pulverized into fine powder to obtain Salvia miltiorrhiza extract, set aside;

[0123] (3) Take 35 g of sweetgum, add 6 times the amount of water to extract the volatile oil for 6 hours, and obtain sweetgum oil, set aside;

[0124] (4) Add the blood dried blood powder in the above step (1), the salvia miltiorrhiza extract in the step (2), add the sweetgum oil in the step (3), mix well, mix with appropriate amount of starch and dextrin, granulate, and press into 1000 tablets.

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Abstract

The invention relates to a traditional Chinese medicine composition for treating a coronary heart disease and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 35-53 parts of resina draconis, 35-53 parts of resina liquidamberis and 95-125 parts of salviae miltiorrhizae; and the raw materials and pharmaceutically acceptable auxiliary materials are prepared into a traditional Chinese medicinal oral preparation according to a certain extraction preparation technology. The traditional Chinese medicine composition provided by the invention has the characteristics of being simple and feasible in preparation technology, safe, effective and obvious in pharmacological and pharmacodynamic functions and clinical test effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating coronary heart disease and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Cardiovascular disease is one of the most common diseases that threaten human health. Among them, the morbidity and mortality of coronary heart disease account for the first place in cardiovascular disease, and there is an upward trend. Coronary heart disease is a clinical syndrome caused by acute, transient ischemia and hypoxia of the myocardium on the basis of coronary atherosclerosis leading to stenosis of the lumen, relatively insufficient coronary blood supply, Chinese medicine plays an important role in its prevention and treatment Traditional Chinese medicine treatment starts with overall regulation, and has irreplaceable advantages in improving clinical symptoms and other aspects of chemically synthesized drugs. [0003] A...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/889A61K36/896A61P9/10
Inventor 赵超
Owner SHAANXI BUCHANG PHARMA
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