Anti-alcoholism agent and preparation method thereof

A technology for hangover and hangover, applied in the field of hangover and its preparation, can solve the problems of unfavorable large-scale industrial production and popularization, limited application, high price, etc., and achieve simple preparation method, reduce absorption, and promote the decomposition of acetaldehyde Effect

Inactive Publication Date: 2015-12-02
CHINA AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These substances are all expensive substances, which are not conducive to large-scale industrial production and promotion, and limit their application.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0023] The preparation method of the broken freeze-dried product of Acetobacter in the following examples is:

[0024] (1) Cultivation of Acetobacter: Acetobacter culture medium is prepared from 41g of yeast extract powder, 10g of glucose, 10ml of glycerin, 50ml of ethanol, 2.1g of sodium chloride, 0.05g of zinc chloride, and 1000ml of distilled water. The initial pH of the medium is 6.8 , inoculating Acetobacterium into the above-mentioned medium, the inoculum amount is 5% of the mass of the medium, and culturing at 30°C for 48 hours after inoculation;

[0025] (2) Preparation of Acetobacter lyophilizate: get the fermentation broth cultivated for 48h and centrifuge for 25min at a speed of 3000r / min in a centrifuge, and the precipitate is washed 3 times with a dipotassium hydrogen phosphate buffer solution with a pH of 8.0 and a concentration of 20mmol / L. Collect the wet cells; weigh the wet cells, suspend in dipotassium hydrogen phosphate buffer solution with a pH of 8.0 and ...

Embodiment 1

[0028] A kind of hangover agent, it comprises the component of following proportioning by weight: 0.05kg of broken freeze-dried product of acetic acid bacteria, 0.05kg of skimmed milk powder, 0.02kg of kudzu flower water extract, 0.02kg of succinic acid, 0.02kg of fumaric acid, L - Glutamine 0.02kg, Ascorbic Acid 0.02kg, Dipotassium Hydrogen Phosphate 0.0015kg, Carboxymethyl Starch Sodium 0.1kg, Dextrin 0.33kg, Corn Starch 0.48kg, Magnesium Stearate 0.015kg, Talc 0.016kg, 10- 20% ethanol aqueous solution 0.15kg.

[0029] The preparation method of above-mentioned hangover agent carries out according to the following steps:

[0030] (1) Prepare the broken freeze-dried product of Acetobacter;

[0031] (2) preparing the kudzu flower water extract;

[0032] (3) Weigh 0.05kg of broken freeze-dried product of Acetobacter, 0.05kg of skimmed milk powder, 0.02kg of kudzu flower water extract, 0.02kg of succinic acid, 0.02kg of fumaric acid, 0.02kg of L-glutamine, 0.02kg of ascorbic ac...

Embodiment 2

[0039] A kind of hangover agent, it comprises the component of following proportioning by weight: 0.01kg of broken freeze-dried product of acetic acid bacteria, 0.01kg of skimmed milk powder, 0.01kg of kudzu flower water extract, 0.01kg of succinic acid, 0.01kg of fumaric acid, L -Glutamine 0.01kg, Ascorbic Acid 0.01kg, Dipotassium Hydrogen Phosphate 0.001kg, Sodium Carboxymethyl Starch 0.09kg, Dextrin 0.315kg, Corn Starch 0.42kg, Magnesium Stearate 0.014kg, Talc 0.014kg, 10- 20% ethanol aqueous solution 0.10kg.

[0040] The preparation method of above-mentioned hangover agent carries out according to the following steps:

[0041] (1) Prepare the broken freeze-dried product of Acetobacter;

[0042] (2) preparing the kudzu flower water extract;

[0043] (3) Weigh 0.01kg of broken freeze-dried product of Acetobacter, 0.01kg of skimmed milk powder, 0.01kg of kudzu flower water extract, 0.01kg of succinic acid, 0.01kg of fumaric acid, 0.01kg of L-glutamine, 0.01kg of ascorbic ac...

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Abstract

The invention belongs to the technical field of Chinese herbal medicine preparations and microbial preparations and discloses an anti-alcoholism agent and a preparation method thereof. The anti-alcoholism agent comprises components in parts by weight as follows: 1-10 parts of an acetobacter aceti broken freeze-dried material, 1-10 parts of skim milk powder, 1-10 parts of a pueraria flower aqueous extract, 1-3.5 parts of succinic acid, 1-4 parts of fumaric acid, 1-4 parts of L-glutamine, 1-4 parts of ascorbic acid, 0.1-0.2 parts of dipotassium phosphate, 9-11 parts of sodium carboxymethyl starch, 31.5-38.5 parts of dextrin, 42.3-51.7 parts of corn starch, 1.4-1.7 parts of magnesium stearate, 1.4-1.7 parts of talc powder and 10-20 parts of a 10%-20% ethyl alcohol aqueous solution. The anti-alcoholism agent can reduce absorption of ethyl alcohol in the stomach and facilitate decomposition of acetaldehyde while protecting the liver and the stomach.

Description

technical field [0001] The invention belongs to the technical field of Chinese herbal medicine preparations and microbial preparations, and in particular relates to an anti-alcoholic agent and a preparation method thereof. Background technique [0002] At present, there are many types of products in the domestic market for sobering up, most of which are traditional Chinese medicine prescriptions, which are decocted and filtered and then packed into oral liquids or tablets. Most hangover products generally reflect that the effect is not obvious among social consumers. Although they have certain liver protection effects, they cannot inhibit the absorption of alcohol in the stomach in time, nor can they promote the metabolic decomposition of acetaldehyde. [0003] Patent 201310401988.8 discloses a food hangover agent. The anti-alcoholic agent is composed of the following components in parts by weight: 5-10 parts of Zhizizi, 20-30 parts of red bean, 5-10 parts of coix seed, 20 ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/48A61P39/02A61K31/194A61K31/375A61K33/12A61K33/42A61K35/741
Inventor 李全宏
Owner CHINA AGRI UNIV
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