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Application of traditional Chinese medicine composition in preparing medicine for treating radiation-induced pulmonary injury

A radiation-induced lung injury and composition technology, which is applied in the direction of drug combinations, active ingredients of hydroxyl compounds, and pharmaceutical formulas, can solve problems such as the application of undisclosed traditional Chinese medicine compositions, and achieve significant curative effects, eliminate pathogenic factors, and relieve symptoms.

Active Publication Date: 2015-11-25
BEIJING YILING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned patent does not disclose the application of the traditional Chinese medicine composition in the preparation and treatment of radiation-induced lung injury

Method used

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  • Application of traditional Chinese medicine composition in preparing medicine for treating radiation-induced pulmonary injury
  • Application of traditional Chinese medicine composition in preparing medicine for treating radiation-induced pulmonary injury
  • Application of traditional Chinese medicine composition in preparing medicine for treating radiation-induced pulmonary injury

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0072] prescription:

[0073] Forsythia 255g Honeysuckle 255g Banlangen 255g Rhubarb 51g

[0074] Patchouli 85g Mianma Guanzhong 255g Rhodiola 85g Menthol 7.5g

[0075] 85 grams of roasted ephedra 85 grams of fried bitter almonds 255 grams of Houttuynia cordata

[0076] 85 grams of licorice and 255 grams of gypsum.

[0077] Preparation:

[0078] (1) Take Chinese medicinal materials according to the above prescription, and select them;

[0079] (2) Patchouli is broken, add 6 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0080] (3) forsythia, ephedra, houttuynia cordata, and rhubarb, extracted twice with 8 times the amount of 70% ethanol, the first time for 2 hours, the second time for 1.5 hours, the extracts were combined and filtered, the ethanol was recovered, and the filtrate was used for later u...

Embodiment 2

[0086] prescription:

[0087] Forsythia 200g Honeysuckle 300g Banlangen 200g Rhubarb 60g

[0088] Patchouli 60g Mianma Guanzhong 300g Rhodiola 60g Menthol 9g

[0089] 60 grams of roasted ephedra 100 grams of fried bitter almonds 200 grams of Houttuynia cordata

[0090] 100 grams of licorice and 200 grams of gypsum.

[0091] Preparation:

[0092] (1) Take Chinese medicinal materials according to the above prescription, and select them;

[0093] (2) Patchouli is broken, add 5 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0094] (3) Forsythia japonicus, roasted ephedra, Houttuynia cordata, and rhubarb were extracted twice with 6 times the amount of 50% ethanol, the first time was 1 hour, and the second time was 2.5 hours, the extracts were combined and filtered, the ethanol was recovered, and the filt...

Embodiment 3

[0100] prescription:

[0101] Forsythia 300g Honeysuckle 200g Banlangen 300g Rhubarb 40g

[0102] Patchouli 100g Mianma Guanzhong 200g Rhodiola 100g Menthol 5g

[0103] 100 grams of roasted ephedra 60 grams of fried bitter almonds 300 grams of Houttuynia cordata

[0104] 60 grams of licorice and 300 grams of gypsum.

[0105] Preparation:

[0106] (1) Take Chinese medicinal materials according to the above prescription, and select them;

[0107] (2) Patchouli is broken, add 8 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0108] (3) forsythia, ephedra, houttuynia cordata, rhubarb, extract twice with 10 times the amount of 90% ethanol, the first time is 3 hours, the second time is 2.5 hours, the extracts are combined and filtered, the ethanol is recovered, and the filtrate is used for later use;

[0...

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Abstract

The invention discloses an application of a traditional Chinese medicine composition in preparing a medicine for treating radiation-induced pulmonary injury. The traditional Chinese medicine composition is mainly composed of fructus forsythiae, honeysuckle flowers, isatis root, rheum officinale, pogostemon cablin, rhizoma dryopteris crassirhizomae and rhodiola rosea, has the integral regulation advantages of compound traditional Chinese medicines, can eliminate pathogenic factors, relieve the symptoms, and adjust immunity, and has a remarkable curative effect for treating radiation-induced pulmonary injury proved by the clinical test.

Description

technical field [0001] The invention relates to the application of a traditional Chinese medicine composition in the preparation of medicines for treating radiation-induced lung injury, and belongs to the field of Chinese herbal medicines. Background technique [0002] Radiation lung injury (radio-pulmonarylesion) is a complication caused by radiotherapy for malignant tumors of the chest. It is most common in lung cancer and breast cancer, followed by radiotherapy for esophageal cancer and mediastinal malignant tumors. The common clinical manifestations are: the medical history of thoracic malignant tumors receiving radiation therapy and related respiratory symptoms. Symptoms generally appear 4 to 16 weeks after the start of radiation therapy, most of which occur within 2 to 4 weeks after the end of radiation therapy, and a few occur in the It can also occur within half a year after the end of radiotherapy, mainly due to dry cough, less sputum, dysphagia, chest tightness, ch...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/78A61P11/00A61K33/06A61K31/045
Inventor 魏聪贾振华常丽萍赵军红
Owner BEIJING YILING PHARMA
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