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Taurine potassium-magnesium compound and preparation method thereof

A technology of potassium taurine and composition, which is applied in the direction of sulfonate preparation, drug combination, anhydride/acid/halide active ingredients, etc., to achieve the effects of increasing absorption rate and utilization rate, improving chest tightness, and increasing yield

Inactive Publication Date: 2015-11-11
邵志辉
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] To sum up, there is no taurine in the market as the main active ingredient for the treatment of cardiovascular diseases, combined with potassium ions and magnesium ions to form a drug for adjusting biological metabolism and effectively treating heart, brain and other organ tissue defects. Compositions for diseases of blood injury

Method used

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  • Taurine potassium-magnesium compound and preparation method thereof
  • Taurine potassium-magnesium compound and preparation method thereof
  • Taurine potassium-magnesium compound and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0032] A potassium magnesium taurine composition is composed of potassium ions, magnesium ions and taurine, wherein the molar ratio of potassium ions, magnesium ions and taurine is 2:1:4.

[0033] 1, the preparation method of potassium magnesium taurine composition

[0034] 1) Put 200 mol of potassium hydroxide and 100 mol of magnesium hydroxide into the reaction kettle at room temperature, add 160 L of water, start stirring to raise the temperature to 80°C and keep it at 80°C to prepare emulsion A;

[0035] 2) Dissolve 400mol of taurine in 100*10 4 ml of water, prepared into 5% taurine solution of 5g / 100ml;

[0036] 3) Add the prepared taurine solution into the reaction kettle with emulsion A, stir and react at 80°C for 5 hours until the emulsion A is clear and transparent, heat up to 92-97°C and reflux for 0.5-1 hour to complete the reaction. Cool down to 89-90°C to obtain product C;

[0037] 4) Put 2kg of activated carbon into the product C, heat and stir for 0.5 hours, ...

Embodiment 2

[0056] A potassium magnesium taurine composition is composed of potassium ions, magnesium ions and taurine, wherein the molar ratio of potassium ions, magnesium ions and taurine is 3:2:7.

[0057] 1, the preparation method of potassium magnesium taurine composition

[0058] 1) Put 300mol of potassium hydroxide and 200mol of magnesium hydroxide into the reactor at room temperature, add 270L of water, start stirring and raise the temperature to 80°C and keep it at 80°C to prepare emulsion A;

[0059] 2) Dissolve 700mol of taurine in 175*10 at room temperature 4 ml of water, prepared into 5% taurine solution of 5g / 100ml;

[0060] 3) Add the prepared taurine solution into the reaction kettle with emulsion A, stir and react at 80°C for 5 hours until the emulsion A is clear and transparent, heat up to 92-97°C and reflux for 0.5-1 hour to complete the reaction. Cool down to 89-90°C to obtain product C;

[0061] 4) Put 5 kg of activated carbon into the product C, heat and stir for ...

Embodiment 3

[0080] A potassium magnesium taurine composition is composed of potassium ions, magnesium ions and taurine, wherein the molar ratio of potassium ions, magnesium ions and taurine is 5:3:11.

[0081] 1, the preparation method of potassium magnesium taurine composition

[0082] 1) Put 500 mol of potassium hydroxide and 300 mol of magnesium hydroxide into the reaction kettle at room temperature, add 320 L of water, start stirring and raise the temperature to 80°C and maintain 80°C to prepare emulsion A;

[0083] 2) Dissolve 1100mol of taurine in 275*10 at room temperature 4 ml of water, prepared into 5% taurine solution of 5g / 100ml;

[0084] 3) Add the prepared taurine solution into the reaction kettle with emulsion A, stir and react at 80°C for 5 hours until the emulsion A is clear and transparent, heat up to 92-97°C and reflux for 0.5-1 hour to complete the reaction. Cool down to 89-90°C to obtain product C;

[0085] 4) Put 5 kg of activated carbon into the product C, heat an...

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Abstract

The invention discloses a taurine potassium-magnesium compound and a preparation method and application thereof. The compound comprises potassium ions, magnesium ions and taurine. The molar ratio of the potassium ions, the magnesium ions and the taurine is (1-8):(1-4):(3-16). The compound can be prepared into various kinds of preparation acceptable in pharmacy, and is mainly used for resisting acute cerebral infarction, coronary heart disease, angina, migraine and the like.

Description

technical field [0001] The invention belongs to the field of medicines, and in particular relates to a potassium magnesium taurine composition and a preparation method thereof, which have significant curative effects on acute cerebral infarction, coronary heart disease, angina pectoris, migraine and other heart and brain tissue ischemic injury diseases. Background technique [0002] With the change of the environment and the acceleration of the pace of life, more and more people are suffering from acute cerebral infarction, coronary heart disease, angina pectoris and migraine and other heart and brain organ tissue ischemic injury diseases, but currently there is no very effective Methods for the prevention and treatment of the above-mentioned diseases. [0003] Taurine has the highest content in natural marine organisms. It is a small molecular substance that can be directly extracted from animals and plants or artificially synthesized. Taurine is one of the eighteen kinds o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/185A61P9/10A61P25/06C07C309/14C07C303/32
Inventor 邵志辉
Owner 邵志辉
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