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A composition and its application for treating liver cancer

A technology for treating liver cancer and a composition, applied in the field of medicine, can solve problems such as no research report on the synergistic effect of Aplysin and β-carotene on liver cancer, etc.

Active Publication Date: 2018-05-01
QINGDAO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] So far, there is no research report on the synergistic effect of aplysia and β-carotene on liver cancer

Method used

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  • A composition and its application for treating liver cancer
  • A composition and its application for treating liver cancer
  • A composition and its application for treating liver cancer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Example 1 a composition

[0047] Raw materials (molar ratio):

[0048] β-carotene: Aplysia = 1:3

Embodiment 2

[0049] Example 2 a composition

[0050] Raw materials (molar ratio):

[0051] β-carotene: Aplysia = 1:2.6

Embodiment 3

[0052] Example 3 a composition

[0053] Raw materials (molar ratio):

[0054] β-carotene: Aplysia = 1:2

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PUM

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Abstract

The present invention provides a composition, including vitamin A or its prodrug, and aplysia; the molar ratio of the two components is: vitamin A or its prodrug: aplysia=1:0.1~3; Vitamin A or a prodrug thereof is preferably β-carotene. The present invention also provides the application of the composition and the composition comprising vitamin A or its prodrug and aplysia in the preparation of medicament for treating liver cancer. The composition of the invention can effectively inhibit the proliferation of liver cancer cells through the synergistic effect of the active components.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a composition comprising aplysia and vitamin A or its prodrug and its medical application in treating liver cancer. Background technique [0002] Hepatocellular carcinoma is one of the most common malignant tumors in China, which has the characteristics of insidious onset, high metastasis rate, and poor prognosis. Although surgery is the first choice and the most effective method for the treatment of liver cancer, chemotherapy is one of the main methods of treatment for inoperable patients. Some patients can also get the chance of surgery because of chemotherapy, which prolongs their lives and improves their quality of life. However, while chemotherapy drugs kill tumor cells, they also cause serious damage to normal cells in the body. Therefore, searching for a highly effective and low-toxic anticancer drug has become the focus of attention in recent years. [0003] Aplysia...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/343A61P35/00A61P1/16A61K31/07
Inventor 刘颖梁惠贺娟韩磊
Owner QINGDAO UNIV
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