Method for preparing toothpaste containing anthocyanin and application thereof
A technology of anthocyanin and toothpaste, which is applied in the fields of dentistry, pharmaceutical formulations, cosmetic preparations, etc., and can solve the problems of anthocyanin instability, affecting the efficacy of toothpaste, and easy oxidation and deterioration.
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preparation example Construction
[0029] Preparation of pomegranate extract:
[0030] (1) Put the peeled pomegranate fruit into a juice extractor, sieve out most of the residues from the squeezed raw juice through a rotary vibrating sieve, keep 9000 parts of the raw juice, and sterilize at low temperature;
[0031] (2) Add 3 parts of pectinase and 3 parts of amylase to the raw juice sterilized in step (1), decompose the pectin and starch in the raw juice, control the temperature at 55° C., and decompose for 1.0 hour;
[0032] (3) Add 60 parts of bentonite moistened by purified water to the juice obtained in step (2), stir and clarify for 50 minutes;
[0033] (4) Carry out high-speed centrifugation to the clarified fruit juice in step (3), remove impurities such as bentonite, and get the supernatant;
[0034] (5) Ultrafiltration is performed on the supernatant obtained in step (4), and the filtrate is dried and concentrated at low temperature, and the finally obtained pomegranate powder is the pomegranate extr...
Embodiment 1-4
[0038] Embodiment 1-4: the preparation method of the toothpaste containing anthocyanins is as follows:
[0039] (1) The weighed sorbitol enters the host;
[0040] (2) The weighed saccharin, sodium benzoate, pomegranate extract, and natural pigment are dissolved in the weighed water and enter the host;
[0041] (3) Mix the weighed CMC and carrageenan evenly, and then turn on the vacuum pump and stir to enter the host;
[0042] (4) The weighed silicon dioxide enters the host when the vacuum pump is turned on and stirred;
[0043] (5) The weighed sodium dodecylbenzenesulfonate and sodium lauroyl sarcosinate are added to the host;
[0044] (6) The weighed essence, including menthol and cooling agent, enters the host;
[0045] (7) Start timing when the vacuum degree reaches -0.094mPa, and the degassing time is 30-40 minutes;
[0046] (8) The paste test is qualified, and the material is discharged;
[0047] (9) The paste is sent to the filling process for filling and packaging ...
experiment example 1
[0048] Experimental Example 1 Study on the Bacteriostatic Effect of Toothpaste Containing Anthocyanins After Stability Test
[0049] The purpose of this test is to further illustrate the present invention by the bacteriostatic effect test after the stability test to toothpaste.
[0050] 1. Stability test
[0051] 1.1 Instruments:
[0052] Refrigerator: Accurate within ±1°C Electric constant temperature incubator: Accurate within ±1°C
[0053] 1.2 Test plan:
[0054] According to the toothpaste standard GB-8372, the toothpaste prepared in Examples 1-4 is tested for stability: take 10 samples of toothpaste, put them in a refrigerator at -8°C, take them out after 8 hours and put them in a constant temperature incubator at 45°C , Take it out after 8 hours, open the cover and check.
[0055] The pomegranate extract of the same quality was tested according to the toothpaste stability test method to observe the color and smell of the pomegranate extract.
[0056] 1.3 Test result...
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