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Water-soluble aseptic medical multifunctional lubricant and preparation method thereof

A multi-functional, lubricant technology, applied in medical science, echo/ultrasonic imaging agents, surgery, etc., can solve the problem of only having lubricating effect but not sterilizing and sterilizing effect, achieving component safety and preventing iatrogenic crossover Infection, good biocompatibility

Inactive Publication Date: 2015-07-15
GUIZHOU JINJIU BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the traditional method generally uses paraffin oil to lubricate surgical instruments. When paraffin oil is used to lubricate surgical instruments, scattered milky white spots often appear on the instruments and curved plates after cleaning, forming a new source of pollution; and it only has lubricating effect and does not have disinfection. Bactericidal effect

Method used

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Experimental program
Comparison scheme
Effect test

Embodiment

[0014] First, weigh the following substances in proportion, Glycerin: 0%-7%, Carbomer ETD 2020: 0.2%-0.6%, Sodium Polyacrylate: 0.0%-4.5%, 70% Sorbitol: 2.5%-6.5% , methylparaben: 0.05-0.18%, ethylparaben: 0.05-0.18%, phenoxyethanol: 0.1%-1.0%, sodium hydroxide or triethanolamine 0.2%-4%, purified water 76.04%-96.9% . Then, methyl paraben and ethyl paraben were completely dissolved in the phenoxyethanol solution; glycerol and 70% sorbitol were added, and stirred evenly; then carbomer and sodium polyacrylate were added to the mixed solution, and Stir continuously to obtain the alcohol phase mixture of carbomer and sodium polyacrylate; finally, slowly add the alcohol phase mixture into deionized water while stirring, then add an appropriate amount of sodium hydroxide or triethanolamine, and adjust the pH value to 6.5-7.0 to obtain a colorless and transparent gel.

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PUM

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Abstract

The invention relates to a water-soluble aseptic medical multifunctional lubricant and a preparation method thereof. The water-soluble aseptic medical multifunctional lubricant is composed of 0 to 7% of glycerin, 0.2 to 0.6% of carbomer 2020, 0.0 to 4.5% of sodium polyacrylate, 2.5 to 6.5% of 70% sorbitol, 0.05 to 0.18% of methylparaben and ethylparaben, 0.1 to 1.0% of phenoxyethanol, 0.2 to 4% of sodium hydroxide or triethanolamine, and 76.04 to 96.9% of purified water. The preparation method comprises following steps: firstly, methylparaben and ethylparaben are completely dissolved in phenoxyethanol; glycerin, and 70% sorbitol are added for uniform stirring; carbomer and sodium polyacrylate are added for stirring; deionized water is added slowly; and pH value is adjusted to be 6.5 to 7.0 with sodium hydroxide or triethanolamine so as to obtain the water-soluble aseptic medical multifunctional lubricant. The preparation method is simple; the raw materials are mild for skin and mucous; bacteria and virus can be killed; cross infection is avoided; and the water-soluble aseptic medical multifunctional lubricant can be widely used for common examination diagnosis and ultrasonic assisted diagnosis and treatment.

Description

Technical field [0001] The invention involves a formula and preparation method of a water -soluble sterile medical multifunctional lubricant. Background technique [0002] Lubricants (liquid) were first used in clinical medicine's examination of the human body. Many medical devices will cause mechanical damage to varying degrees in the human body. Lubricants can minimize damage to body tissue and mucous membranes. At the same time, in ultrasoundWhen imaging, as an excellent sound medium, it can fill the tiny gaps of the probe and the surface of the skin, reduce the sound resistance resistance between the probe and the skin.Make the probe flexibly sliding to detect. [0003] Commonly used medical devices are mostly iron equipment, with nickel chromium plating on the surface.When the nickel chromium layer is destroyed, the impure iron (carbon containing) is exposed to the air, and oxidation reactions will occur when contacting oxygen and water, thereby rusting. The use of medical s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/14A61L31/16A61K49/22
Inventor 韩克兵
Owner GUIZHOU JINJIU BIOTECH
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