Use of traditional Chinese medicine composition for preparing medicines for dental ulcer related to radiotherapy and chemotherapy for tumors

A technology for oral ulcers and compositions, which is applied in the new pharmaceutical application field of traditional Chinese medicine compositions, can solve the problems of different treatment requirements, difficult treatment, caused by lack of hormones, caused by women's menstruation, caused by digestive system diseases, and diabetes. and other problems caused by tumor radiotherapy and chemotherapy, to achieve the effect of improving tolerance

Active Publication Date: 2015-07-08
贵州三力制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is only aimed at conventional oral ulcers, and different oral ulcers are caused by different causes. Although the disease appearance is similar, the treatment is quite different. For example, oral ulcers are caused by conventional fire, vitamin deficiency, and women's menstrual period. , d...

Method used

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  • Use of traditional Chinese medicine composition for preparing medicines for dental ulcer related to radiotherapy and chemotherapy for tumors
  • Use of traditional Chinese medicine composition for preparing medicines for dental ulcer related to radiotherapy and chemotherapy for tumors
  • Use of traditional Chinese medicine composition for preparing medicines for dental ulcer related to radiotherapy and chemotherapy for tumors

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Effect test

Embodiment 1

[0012] The drug prescription of the present invention:

[0013] Octopus Golden Dragon 313g, Shandougen 313g, Cicada Mould 250g, Menthol 1g.

[0014] The preparation method is as follows: the three medicinal materials of Bajiao Jinlong, Shandougen, and Cicada slug, add water and decoct twice, the first time is 2 hours, the second time is 1 hour, the decoction is combined, filtered, and concentrated to a relative density of 1.05~1.10 ( Add ethanol to the clear extract at 50°C to make the alcohol content reach 80%, let it stand for 24 hours, and filter. The filtrate is decompressed to recover the ethanol and concentrate into an extract with a relative density of 1.10 to 1.20 (80°C). Take mint After stirring and dissolving brain, sodium benzoate 5.5ml, citric acid 1g and bayberry flavor 1g with 20ml ethanol, add the above extract, add water to 1000ml, stir evenly, filter, canned, and get ready.

[0015] Examples of clinical or pharmacological effects:

[0016] 1. Treatment of oral ulcers...

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Abstract

The invention belongs to the field of medicines, particularly use of a traditional Chinese medicine composition for preparing medicines for dental ulcer related to radiotherapy and chemotherapy for tumors. The active ingredients include ardisia crenata sims, subprostrate sophora, periostracum cicada and menthol. The preparation prepared by using the composition for treating dental ulcer induced by radiotherapy and chemotherapy for tumors is remarkable in curative effect. In addition, the composition further plays the roles in reducing the dental ulcer occurrence rate induced by radiotherapy and chemotherapy for tumors, reducing the secondary rate of dental ulcer induced by repeated radiotherapy and chemotherapy for tumors and stimulating oral keratinocyte to proliferate.

Description

Technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and specifically relates to a new pharmaceutical use of a traditional Chinese medicine composition, which includes various uses in oral ulcers caused by tumor radiotherapy and chemotherapy. Background technique [0002] Radiochemotherapy has always been the traditional treatment method for malignant tumors. Its biggest side effect is that it kills normal cells while also killing normal cells, thereby causing damage to tissues and organs. Studies have shown that among patients receiving high-dose chemotherapy, the incidence of oral ulcers is 100%, which increases the suffering of patients and affects the treatment and prognosis of tumors. If such oral ulcers are not treated in time, the degree of ulcers will continue to increase. In severe cases, it can cause systemic infections and eventually lead to the interruption or failure of treatment. At present, there is no specific treatm...

Claims

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Application Information

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IPC IPC(8): A61K36/489A61K9/12A61P1/02A61K35/64A61K31/045
Inventor 张海
Owner 贵州三力制药股份有限公司
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