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A compound red coat blood tonifying pharmaceutical preparation and its application and detection method

The technology of a pharmaceutical preparation and red clothing is applied in the field of compound red clothing blood-enriching pharmaceutical preparations, which can solve the problems of complex process, high price, insignificant effect and the like, and achieves the effects of broad application prospect, low cost, remarkable and reliable curative effect and the like.

Active Publication Date: 2018-01-30
XIANGYU PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, there are many drugs clinically used to replenish blood, but most of them have defects such as high price, complicated process, and insignificant effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A compound red coat blood tonifying drug preparation, which is prepared from the following raw materials in weight ratio:

[0029] 60 parts of peanut red coat, 50 parts of jujube, 50 parts of astragalus, 50 parts of Eclipta, 40 parts of Polygonum multiflorum,

[0030] 40 parts of cinnamon, 40 parts of mulberry fruit, 40 parts of Ligustrum lucidum, 40 parts of raspberry, 40 parts of Atractylodes macrocephala,

[0031] 40 parts of papaya, 35 parts of licorice, 35 parts of poria cocos, 35 parts of dandelion, 35 parts of Sijiqing,

[0032] 30 parts of frankincense, 30 parts of green skin, 30 parts of comfrey, 30 parts of jujube seed, 30 parts of myrrh,

[0033] Guizhi 20 parts, Salvia miltiorrhiza 20 parts, Morinda officinalis 20 parts, Lycium barbarum 20 parts, Albizia juniper bark 20 parts, Coix seed 20 parts.

[0034] The preparation method of described pharmaceutical preparation is as follows:

[0035] Take by weighing above-mentioned crude drug according to above-me...

Embodiment 2

[0041] Toxicity test:

[0042]In this experiment, healthy SD rats were used, and the dosage gradient of the drug prepared in Example 1 was administered orally at 0.01g / kg and 0.1g / kg, and the drug was administered continuously for 30 days. Animal growth status, activity diet, hematology, blood biochemistry, organ tissue structure and urine routine were not significantly affected, indicating that the clinical medication is safe and reliable.

Embodiment 3

[0044] Summary of clinical efficacy:

[0045] General information, the pharmaceutical preparation of the present invention is applied to 108 cases of clinical observation, and all subjects are divided into 2 groups on average, control group and experimental group, each group of 54 people, two groups of cases are statistically analyzed in terms of gender, age, course of disease, etc. Analysis is comparable.

[0046] The diagnostic criteria formulated by WHO in 1972 considered that anemia was diagnosed when Hb was lower than the following levels in sea level areas: 110g / L for children aged 6 months to <6 years, 120g / L for children aged 6-14, 130g / L for adult males, and 130g / L for adults. 120g / L for women and 110g / L for pregnant women. It should be noted that the normal hemoglobin value of residents living in plateau areas is higher than that of sea-level residents; during pregnancy, hypoalbuminemia, congestive heart failure, splenomegaly, and macroglobulinemia, plasma volume in...

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PUM

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Abstract

The present invention relates to a compound red coat blood-enriching drug preparation and its application and detection method. The preparation is prepared from the following raw materials: peanut red coat, jujube, astragalus, Eclipta chinensis, Polygonum multiflorum, cinnamon, and mulberry Ligustrum lucidum, raspberry, Atractylodes macrocephala, papaya, licorice, Poria cocos, dandelion, Sijiqing, frankincense, green bark, comfrey, jujube seed, myrrh, cassia twig, salvia miltiorrhiza, Morinda officinalis, medlar, acacia bark. Carry out alcohol extraction and decoction for the active ingredients of traditional Chinese medicine to prepare capsules. The compound red coat blood-tonifying pharmaceutical preparation of the present invention is applied dialectically on the basis of the prior art. , has been clinically verified to have a good therapeutic effect on anemia and has broad application prospects.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a compound red coat blood-tonifying drug preparation and its application and detection method. Background technique [0002] Anemia refers to a common clinical symptom in which the volume of red blood cells in the peripheral blood of the human body is low, which is lower than the lower limit of the normal range. Because the determination of red blood cell volume is complicated, it is often replaced by hemoglobin (Hb) concentration in clinical practice. The main causes of anemia are: (1) iron deficiency; (2) decreased EPO production; (3) metabolic poisons inhibit the proliferation of red blood cells; (4) inflammatory factors accelerate the removal of antibodies or immune complexes in the circulation (5) The increased generation of reactive oxygen species in CKD patients makes red blood cells prone to hemolysis. Clinical manifestations: (1) Nervous system:...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8994A61P7/06
Inventor 林凡儒徐步玺王言玉罗晓倩刘倩
Owner XIANGYU PHARMA
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