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Pharmaceutical composition for treating stable angina

A composition and technology of angina pectoris, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve problems such as poor treatment of angina pectoris and poor quality of life of patients

Inactive Publication Date: 2015-06-10
尹文波 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The purpose of the present invention is to provide a new traditional Chinese medicine for angina pectoris and its preparation method, so as to solve the problem that existing medicines cannot treat angina pectoris well and the quality of life of patients is poor.

Method used

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  • Pharmaceutical composition for treating stable angina
  • Pharmaceutical composition for treating stable angina

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Example 1 Danshen 180g, safflower 180g, astragalus 160g, hawthorn 160g, schisandra 150g, notoginseng 150g, scallion white 120g, melon peel 120g, citrus aurantium 100g, red peony 100g, musk 100g

[0047] The preparation method of the granule of the present invention: take the above pharmaceutical composition raw materials and mix them, crush them into coarse particles of 10-20 mesh, add 6 times (volume) of 60% ethanol, and use microwave extraction method to extract three times continuously at 60°C. Centrifugal separation, the net infusion is concentrated to a thick paste with a relative density of 1.20 to 1.30, vacuum dried, and the dry paste is crushed, add 1000 g of compressible starch, 500 g of sodium carboxymethyl cellulose, mix and pass through an 80 mesh sieve, add appropriate amount of water Granulate, dry under reduced pressure at 60°C, sizing, and pack into bags to obtain.

Embodiment 2

[0048] Example 2 Salvia Miltiorrhiza 190g, Safflower 185g, Astragalus 170g, Hawthorn 165g, Schisandra 160g, Panax notoginseng 160g, Scallion White 110g, Trichosanthes skin 130g, Citrus aurantium 110g, Red Peony Root 110, Musk 110g

[0049] The preparation method of the hard capsule of the present invention: take the above pharmaceutical composition raw materials and mix them, crush them into coarse particles of 10-20 mesh, add 6 times (volume) of 60% ethanol, and use the microwave extraction method to extract three times continuously at 60°C. After centrifugal separation, the net infusion is concentrated to a thick paste with a relative density of 1.20 to 1.30, dried in a vacuum, and the dry paste is crushed and filled into capsules to obtain.

Embodiment 3

[0050] Example 3 Salvia miltiorrhiza 170g, safflower 175g, astragalus 160g, hawthorn 150g, schisandra 155g, panax notoginseng 140g, scallion white 110g, melon peel 110g, citrus aurantium 90g, red peony 95g, musk 90g

[0051] The preparation method of the tablet of the present invention: take the above pharmaceutical composition raw materials and mix them, crush them into coarse particles of 10-20 mesh, add 6 times (volume) of 60% ethanol, and use the microwave extraction method to extract three times continuously at 60°C. Centrifugal separation, the net infusion is concentrated to a thick paste with a relative density of 1.20-1.30, vacuum dried, the dry paste is pulverized, starch, talc and magnesium stearate are added in an appropriate amount, granulated, compressed into tablets, and coated, ready to be obtained.

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PUM

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Abstract

The invention relates to a pharmaceutical composition for treating stable angina and preparation method thereof. The pharmaceutical composition for treating stable angina is composed of salviae miltiorrhizae, flos carthami, radix astragali, hawthorn fruits, fruits of Chinese magnoliavine, pseudo-ginseng, longstamen onion bulb, snakegourd peel, fructus aurantii, red peony roots and musk. The forms of the pharmaceutical composition comprise a hard capsule form, a tablet form and a granule form. The pharmaceutical composition for treating stable angina has an exact curative effect, can lower the level of MDA and ET, and can well reduce damage caused by hypoxia.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a pharmaceutical composition for treating angina pectoris and a preparation method thereof. Background technique [0002] Angina pectoris is a clinical syndrome characterized by episodic chest pain or chest discomfort caused by insufficient coronary blood supply, rapid myocardial ischemia, and hypoxia. It is characterized by paroxysmal and squeezing pain in the front chest, which may be accompanied by Other symptoms. The pain is mainly located at the back of the sternum and can radiate to the precordial area and left upper limb. It often occurs during labor or emotional excitement. Each attack lasts for 3 to 5 minutes. It can be once a few days or several times a day. Rest or use Disappeared after nitrate preparation. This disease is more common in men, most of which are over 40 years old. Tiredness, emotional agitation, fullness, cold, rainy weather, acute circulatory fa...

Claims

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Application Information

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IPC IPC(8): A61K36/8962A61P9/10A61K35/55
Inventor 张春
Owner 尹文波
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