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A kind of cadaver specimen angiography filler and preparation method thereof

An angiography and filler technology, which is applied in the field of cadaveric angiography filler and its preparation, can solve the problems of unquantified perfusion volume, easy to produce artificial artifacts, and large amount of lead oxide, so as to achieve rapid self-coagulation and improve Clinical diagnosis and treatment level, the effect of strong toughness

Inactive Publication Date: 2017-06-16
黄海龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in practice, it is found that the "gold standard" still has some deficiencies: (1) the amount of lead oxide is too large, which is prone to artificial artifacts; (2) the amount of gelatin used as a carrier is insufficient; (3) the amount of perfusion has not been quantified, and it is easy to overdo or insufficient

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] An angiography filler and a preparation method thereof. The filler is composed of E-51 epoxy resin, 2,4,6-tris(dimethylaminomethyl)phenol (DMP-30), polypropylene glycol diglycidyl Ether (D-1217), T-31 epoxy resin curing agent, zinc oxide composition.

[0025] 1 The angiography filler of the present invention is prepared in the following proportions:

[0026] E-51 type epoxy resin: 100ml

[0027] 2,4,6-Tris(dimethylaminomethyl)phenol (DMP-30): 1ml

[0028] Polypropylene glycol diglycidyl ether (D-1217): 19-20ml

[0029] T-31 epoxy resin curing agent: 24ml

[0030] Zinc oxide: 50-55g

[0031] 2. The specific operation of preparing angiography filler of the present invention:

[0032] Use a plastic syringe to extract 100ml of E-51 epoxy resin, 19-20ml of polypropylene glycol diglycidyl ether (D-1217), 24ml of T-31 epoxy resin curing agent, 2,4,6-tris(dimethylamino) Methyl)phenol (DMP-30) 1ml was poured into a 400ml beaker, and 50-55g of metal oxide powder contrast ag...

Embodiment 2

[0034] An angiography filler and a preparation method thereof. The filler is composed of E-51 epoxy resin, 2,4,6-tris(dimethylaminomethyl)phenol (DMP-30), polypropylene glycol diglycidyl Ether (D-1217), T-31 epoxy resin curing agent, titanium dioxide composition.

[0035] 1 The angiography filler of the present invention is prepared in the following proportions:

[0036] E-51 type epoxy resin: 100ml

[0037] 2,4,6-Tris(dimethylaminomethyl)phenol (DMP-30): 1ml

[0038] Polypropylene glycol diglycidyl ether (D-1217): 9-15ml

[0039] T-31 epoxy resin curing agent: 28ml

[0040] Titanium dioxide: 25-30g

[0041] 2. The specific operation of preparing angiography filler of the present invention:

[0042] Use a plastic syringe to extract 100ml of E-51 epoxy resin, 9-15ml of polypropylene glycol diglycidyl ether (D-1217), 28ml of T-31 epoxy resin curing agent, 2,4,6-tris(dimethylamino) Methyl) phenol (DMP-30) 1ml is poured into a 400ml beaker, and 25-30g of metal oxide powder c...

Embodiment 3

[0044] An angiography filler and a preparation method thereof. The filler is composed of E-51 epoxy resin, 2,4,6-tris(dimethylaminomethyl)phenol (DMP-30), polypropylene glycol diglycidyl Ether (D-1217), T-31 epoxy resin curing agent, cuprous oxide.

[0045] 1 The angiography filler of the present invention is prepared in the following proportions:

[0046] E-51 type epoxy resin: 100ml

[0047] 2,4,6-Tris(dimethylaminomethyl)phenol (DMP-30): 1ml

[0048] Polypropylene glycol diglycidyl ether (D-1217): 13-15ml

[0049] T-31 epoxy resin curing agent: 24ml

[0050] Cuprous oxide: 75-85g

[0051] 2. The specific operation of preparing angiography filler of the present invention:

[0052] Use a plastic syringe to extract 100ml of E-51 epoxy resin, 13-15ml of polypropylene glycol diglycidyl ether (D-1217), 24ml of T-31 epoxy resin curing agent, 2,4,6-tris(dimethylamino) Methyl) phenol (DMP-30) 1ml was poured into a 400ml beaker, and 75-85g of metal oxide powder contrast agent c...

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Abstract

The invention relates to an angiography technology and an anatomy and casting technology of a body sample and specifically discloses a body sample angiographic filler and a preparation method thereof. The filler consists of E-51 epoxy resin, 2,4,6-tri(dimethylamino methyl) phenol (DMP-30), polypropylene glycol diglycidyl ether (D-1217), a T-31 epoxy resin curing agent and a metal oxide powder contrast agent (zinc oxide, titanium dioxide, cuprous oxide and chromium sesquioxide). The angiographic filler disclosed by the invention is simple to prepare, easy to regulate in concentration and color and hard to decolorize, and has the characteristics of being rapid in automatic coagulation, small in percentage of contraction, high in toughness, low in cost and the like. CT reconstruction of blood vessel images of a human body sample or an animal body sample (or organ) have the advantages of being clear, full, continuous, free of fake shadows and burrs and the like.

Description

technical field [0001] The invention relates to angiography technology and anatomical casting technology of cadaveric specimens. [0002] technical background [0003] Since 1990, many countries have invested a lot of talent and financial resources in the "Visible Human (VH) Program", and achieved gratifying breakthrough results. However, during the processing of the VH dataset, the small blood vessels could not be segmented. Even the powerful and technically advanced Voxel-man researchers could only use the TubeEditor to artificially simulate small blood vessels. In 2002, Chinese anatomists used a combination of angiography technology and anatomical casting technology to successfully reconstruct some human blood vessels from the "Chinese Digital Human (CDH)" dataset for the first time in the world. (Digital Human, DH)” has made a significant contribution. At present, gelatin-lead oxide angiography has become a routine method for the study of vascular anatomy, and has been ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C08L63/00C08K3/22
Inventor 黄海龙李力强龚达聪张灼荣梁昆陈淑婷陈倩怡吴湖广
Owner 黄海龙
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