Anti-drunkenness alcohol-effect-dispelling potentilla fulgens Wall extractive and application thereof

A technology of turning white leaves and extracts, which is applied in the field of turning white leaf extracts, and achieves the effect of good antiemetic effect, significant anti-drunk and sobering effect, and prolonging the effect of drunken incubation period.

Inactive Publication Date: 2015-04-08
李健
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no report in the literature that the extract of the leaves of the leaves has the effect of anti-drunkness and hangover

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Example 1 The preparation of the leaf extract

[0017] Remove the impurities from the white leaves, clean them, crush them, weigh 10kg of the white leaves powder, put them in a reflux extraction device, add 85L of purified water to soak for 1 hour, then heat and reflux for 1 hour of extraction, extract twice in total, remove the precipitate and combine the extracts , centrifuged at a speed of 6000 rpm, and the supernatant was concentrated under reduced pressure (conditions for concentration under reduced pressure: concentration temperature 80°C, vacuum degree -0.08~-0.1Mpa) to the extract, freeze-dried with a freeze dryer, crushed, Get the white leaf extract.

Embodiment 2

[0018] Example 2 The preparation of the leaf extract

[0019] Remove the impurities from the white leaves, clean them, crush them, weigh 10kg of the white leaves powder, put them in a reflux extraction device, add 100L of purified water to soak for 1 hour, then heat and reflux for 1.5 hours of extraction, extract twice in total, remove the precipitate and then combine and extract liquid, centrifuged at 8000 rpm, and the supernatant was concentrated under reduced pressure (conditions for concentration under reduced pressure: concentration temperature 80°C, vacuum degree -0.08~-0.1Mpa) to the extract, freeze-dried with a freeze dryer, crushed , to get the leaf extract.

Embodiment 3

[0020] Example 3 Preparation of enteric-coated tablets

[0021] Weigh 50 g of the leaf extract prepared in Example 1, and weigh 240 g of starch, 150 g of powdered sugar, and 3 g of magnesium stearate. Take 40g of starch, add appropriate amount of water to make starch paste; use starch paste as a binder, wet granulate on the mixed raw and auxiliary materials of vermicelli leaf extract, starch and powdered sugar, air dry, granulate, and then add stearic acid After the magnesium is compressed into tablets, 1000 tablets are compressed to obtain tablet cores. Enteric-coated acrylic resin is used as a coating material to coat the tablet core with a film coat to obtain an enteric-coated tablet.

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PUM

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Abstract

The invention discloses an anti-drunkenness alcohol-effect-dispelling pharmaceutical composition and application thereof, and the pharmaceutical composition is prepared from potentilla fulgens Wall extractive and pharmaceutically-usable auxiliary materials. Potentilla fulgens Wall extractive is capable of rapidly decomposing ethanol in human body and obviously prolonging incubation period of drunkenness, thereby enabling the pharmaceutical composition to have obvious anti-drunkenness alcohol-effect-dispelling effect. Potentilla fulgens Wall extractive is capable of alleviating nausea, vomit, skin abnormity and other symptoms after drunkenness, and can be used to exploit medicines, food and health-care products for resisting drunkenness or dispelling alcohol effect.

Description

technical field [0001] The invention belongs to the technical field of medicine extraction, and in particular relates to an anti-drunkness and anti-alcoholic anti-drunkness extract and application thereof, which can alleviate symptoms such as nausea, vomiting, and skin abnormalities after drinking. Background technique [0002] Alcoholism and drunkenness cause physical discomfort. Traditional Chinese medicine has called it "alcohol poisoning". Excessive drinking has become a serious public health problem in my country. Acute heavy drinking can cause nausea, vomiting, memory loss, inattention, and impaired fine motor ability. And emotional instability, can be fatal due to respiratory muscle paralysis in severe cases. In the past ten years in my country, the alcohol consumption group has become increasingly large, and the number of alcohol poisoning, especially acute alcohol poisoning, has increased sharply. The development of low-toxic and effective anti-drunk and hangover dru...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/73A23L1/29A61P39/02A61P25/00A61P1/08A23L33/00
CPCA23V2002/00A61K9/284A61K36/73A61K2236/331A23V2200/334A23V2250/21
Inventor 李健
Owner 李健
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