Synthetic method of p-chlorobenzaldehyde

Abstract

The invention discloses a synthetic method of p-chlorobenzaldehyde. The synthetic method comprises the following steps: performing illumination and chlorine reaction on p-chlorotoluene in the presence of a phosphorus trichloride initiator to generate p-chlorobenzal chloride, refining, and then performing catalytic hydrolysis for 6-12 hours to obtain p-chlorobenzaldehyde. The synthetic method of p-chlorobenzaldehyde, disclosed by the invention, is good in selectivity and high in yield.

Description

Technical field [0001] The invention belongs to the technical field of organic synthesis, and specifically relates to a synthesis method of p-chlorobenzaldehyde. [0002] Background technique [0003] p-Chlorobenzaldehyde is an important new pesticide, pharmaceutical, and dye intermediate. In medicine, p-chlorobenzaldehyde can be produced through condensation and cyclization reaction with mercaptopropionic acid. In terms of pesticides, p-chlorobenzaldehyde is used to synthesize the herbicide Maidisan, plant growth regulators paclobutrazol and Uniconazole, etc. In terms of dyes, p-chlorobenzaldehyde is used to synthesize acid blue 7BF, acid brilliant blue 6B, etc. [0004] The country that produces p-chlorobenzaldehyde abroad is mainly the United States, which is at the leading level in process technology development and has achieved industrial production. Although the research and development of p-chlorobenzaldehyde in my country started late, it has developed rapidly in...

AI Technical Summary

Problems solved by technology

At present, the total domestic production is less than 1000t / a, which is far from meeting the domestic market demand of more than 2500t / a