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A feed additive for improving oxidative stress in dairy cows and its application method

A feed additive, oxidative stress technology, applied in applications, animal feed, additional food elements, etc.

Active Publication Date: 2017-09-19
HUNAN TAIFENG ANIMAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional dairy cow health care and udder protection are dominated by antibacterial enhancement, which to a certain extent ignores the harm of oxidative stress to mammary gland health. The main means to effectively prevent oxidative stress is to feed antioxidants to dairy cows, but there is no direct way to prevent oxidative stress. Drugs or feed additives for antioxidant intervention on dairy cows are available on the market. Therefore, the applicant has developed a high-efficiency antioxidant preparation with a new component in view of the increasing demand for such products in the current market, which can prevent or alleviate the effects of Oxidative stress, corrects oxidative imbalance in dairy cows, protects mammary glands from oxidative damage, and improves milk production

Method used

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  • A feed additive for improving oxidative stress in dairy cows and its application method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] 1. Weigh 50 parts of kudzu root, 30 parts of buckwheat leaves, and 20 parts of licorice, mix them and crush them, pass through a 60-mesh sieve, extract with 70% ethanol under reflux for 3 hours, filter, and concentrate and dry the filtrate at 45°C to obtain the compound kudzu root extract. Drugs account for 1% -2% of the original drug.

[0018] 2. Pre-mixing Mix 6g of compound kudzu root extract with 600g of sepiolite; mix 6.6g of vitamin A, 1.5g of vitamin E with 400g of bran.

[0019] 3. Mixing Add 0.5 g of tert-butyl hydroquinone to the above two pre-mixtures and stir to make the mixture even.

[0020] 4. The laboratory technician will test the indicators of mixing uniformity, effective substance content, water content and loading capacity.

[0021] 5. Packing and storage.

Embodiment 2

[0023] 1. Weigh 60 parts of kudzu root, 25 parts of buckwheat leaves, and 15 parts of licorice, mix them and crush them, pass through a 60-mesh sieve, extract with 80% ethanol under reflux for 2.5 hours, filter, concentrate and dry the filtrate at 45°C to obtain the compound kudzu root extract, extract Drugs account for 1% -2% of the original drug.

[0024] 2. Pre-mixing Mix 8g of compound kudzu root extract with 700g of sepiolite; mix 8.8g of vitamin A and 2.5g of vitamin E with 300g of bran.

[0025] 3. Mixing Add 1g of tert-butyl hydroquinone to the above two pre-mixtures and stir to make the mixture even.

[0026] 4. The laboratory technician will test the indicators of mixing uniformity, effective substance content, water content and loading capacity.

[0027] 5. Packing and storage.

Embodiment 3

[0029] Comparative study on antioxidant activity in vivo

[0030] 1. Materials and methods

[0031] Select 40 Chinese Holstein dairy cows with similar body weight, calving age, milk production and parity, and divide them into 4 groups randomly. Vitamin E 100mg / day / head, test 2 groups added daidzein 400mg / day / head, test 3 groups added the additive 50g / day / head prepared in Example 1 of the present invention, the test period was 20 days, and the test was collected 2 times head by head before and after the test For milk samples, the activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and MDA value were detected with a kit.

[0032] 2. Test results

[0033] It can be seen from Table 1 that all the antioxidant indexes in this test were significantly different from the control group (P<0.01), while the vitamin E group and daidzein group were significantly different from the control group (P<0.05). ), proving that the feed additive of the present invention has...

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Abstract

The invention discloses a feed additive for improving oxidative stress of dairy cows and an application method thereof, which mainly consists of three plant extracts, two reducing vitamins and a carrier. Compared with commonly used dairy cow feed additives and breast health drugs, it has a new effect, which can help resist oxidative stress caused by various stressors in dairy cows, remove free radicals in the body, protect mammary gland tissue from oxidative damage, and improve Milk production and milk quality of dairy cows.

Description

Technical field: [0001] The invention belongs to the field of feed additives, and in particular relates to a feed additive capable of eliminating free radicals in dairy cows, resisting oxidative damage, and improving oxidative stress suffered by dairy cows and its application. Background technique: [0002] Dairy cows are prone to oxidative stress due to high-intensity metabolism. For example, the lactation period of dairy cows is as long as 300 days, and a large amount of milk is secreted every day. The material metabolism and oxygen consumption are at a very high level, coupled with environmental stress The addition of lipids in the diet puts dairy cows in a state of oxidative stress for a long time, which has a negative impact on their health and production capacity, especially the mammary gland, which is a commonly used functional organ, has more serious oxidative damage. It has been reported that oxidative stress and dairy cows The incidence of mastitis is correlated an...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23K50/10A23K20/174A23K20/10A23K20/20
Inventor 禹善秋
Owner HUNAN TAIFENG ANIMAL PHARMA
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