Degradable human body stent capable of effectively preventing transposition and reducing hyperplasia and manufacturing method

Abstract

The invention relates to a degradable human body stent capable of effectively preventing transposition and reducing hyperplasia. The degradable human body stent is characterized by comprising a reticulate body structure, a skirt stacking type degradable laminating membrane, at least one developing sign and a covering membrane. The skirt stacking type degradable laminating membrane and the developing sign are additionally arranged on multiple sections of reticulate bodies to be used for identifying the human body implantation position of the human body stent during human body developing. The reticulate body structure is composed of the multiple sections of reticulate bodies, and the multiple sections of reticulate bodies are connected in series, so that the multiple sections of reticulate bodies are bent to a certain degree relative to others under the stress effect, and a channel is formed between the multiple sections of reticulate bodies. The multiple sections of reticulate bodies are formed by degradable materials. The peripheries of the multiple sections of reticulate bodies are covered by the covering membrane, the membranes of the whole stent are like fish scales, and one section of skirt is stacked below a next section of skirt. The one or more developing signs are additionally arranged on the multiple sections of reticulate bodies to be used for identifying the human body implantation position of the human body stent during human body developing.

Description

technical field [0001] The invention relates to a degradable human body support capable of effectively preventing displacement and reducing hyperplasia and a manufacturing method thereof, especially its unique covering method and fixing knot. Background technique [0002] Esophageal benign and malignant strictures are one of the main clinical problems that digestive endoscopists need to solve. For benign and malignant esophageal strictures, the current common treatment methods include esophageal stricture dilation or esophageal stent placement. In the treatment of esophageal stricture, the commonly used stent is nickel-titanium alloy self-expanding metal stent (self-expanding stent, SES). However, the metal stent is a foreign body to the human body. Long-term placement of SES in the treatment of benign esophageal strictures will cause excessive proliferation of the esophageal mucosa, aggravate dysphagia, and even cause complications such as perforation; at the same time, a ...

AI Technical Summary

Problems solved by technology

However, at present there are only clinical reports of biodegradable esophageal stents implanted with polydioxanone as a whole, and the complications are relatively serious, such as benign esophageal stenosis due to transient expansion, and subsequent hyperplasia of esophageal mucosa due to stimulation, Even lead to restenosis, while the rate of stent migration is quite high

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