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Pharmaceutical composition for treating osteoporosis

An osteoporosis and composition technology, applied in the directions of drug combinations, bone diseases, pharmaceutical formulations, etc., can solve the problems of high price, obvious side effects, induced breast cancer, etc., achieve the treatment of osteoporosis, no toxic side effects, and dosage small effect

Inactive Publication Date: 2015-02-25
CHENGDU GUORUI PHARMA TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of these drugs are expensive and have obvious side effects
And there are related reports that long-term use of estrogen may induce breast cancer
Due to the difference in calcium absorption capacity of patients, the curative effect of calcitonin and calcium preparations is not satisfactory, and other therapies can only be used as adjuvant therapy
[0004] Therefore, the incidence rate of clinical osteoporosis is very high, but there is a lack of safe and effective drugs, and it is necessary to actively develop drugs for the treatment of osteoporosis.

Method used

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  • Pharmaceutical composition for treating osteoporosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] The pharmaceutical composition for the treatment of osteoporosis described in the present embodiment is made of the raw materials of following weight:

[0030] Salvia 6g, cornflower 6g, elderberry 3g, gallnut 3g, walnut 3g and licorice 1g.

[0031] Add 9 times the volume of 75% ethanol to the raw materials in the above weight ratio, reflux extraction three times, the extraction time is 2.0h, 1.5h, 1.5h respectively, filter, combine the filtrates for 3 times, recover the ethanol and concentrate, and then concentrate each Mix the solution evenly, dry, add 60g of dextrin, make granules according to the preparation technology of granules, and pack into 10g / bag.

Embodiment 2

[0033] The pharmaceutical composition for the treatment of osteoporosis described in the present embodiment is made of the raw materials of following weight:

[0034] Salvia 2g, cornflower 7g, elderberry 2g, gallnut 8g, walnut 5g and licorice 2g.

[0035] Add 8 times the volume of 70% ethanol to the raw materials in the above weight ratio, reflux extraction three times, the extraction time is 2.0h, 1.5h, 1.5h respectively, filter, combine the filtrates for 3 times, recover the ethanol and concentrate, and then concentrate each The liquid is mixed uniformly, dried, then mixed with 50g of starch and 10g of povidone, and the pharmaceutical composition of tablets is obtained by using the existing tabletting technology.

Embodiment 3

[0037] The pharmaceutical composition for the treatment of osteoporosis described in the present embodiment is made of the raw materials of following weight:

[0038] Salvia 8g, cornflower 3g, elderberry 5g, gallnut 4g, walnut 1g and licorice 3g.

[0039] Add 8 times the volume of 60% ethanol to the raw materials in the above weight ratio, reflux extraction three times, the extraction time is 2.0h, 1.5h, 1.5h respectively, filter, combine the filtrates for 3 times, recover the ethanol and concentrate each concentration Liquid mixed evenly, dried; then mixed with 60g sucrose, divided into 10g / bag, made into powder.

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Abstract

The invention discloses a pharmaceutical composition for treating osteoporosis. The pharmaceutical composition is prepared from raw materials including salvia miltiorrhiza, cornflowers, elderberry, gallnuts, walnuts and liquorice. The pharmaceutical composition has the effects of tonifying the liver and kidneys, strengthening bone and relieving pain and can be used for effectively treating osteoporosis with symptoms such as lumbar spine pain, muscle ache and weakness, incapability of bearing heavy objects, dizziness, bone joint pain, limb numbness and the like. The pharmaceutical composition disclosed by the invention is exact in curative effect, small in dosage and free of toxic or side effect on human bodies.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating osteoporosis, in particular to a pharmaceutical composition made of salvia miltiorrhiza, cornflower, elderberry, gallnut, walnut and licorice as raw materials. Background technique [0002] Osteoporosis is a group of bone diseases caused by various reasons. There is normal calcification of bone tissue, and the ratio of calcium salt to matrix is ​​normal. It is a metabolic bone lesion characterized by a decrease in the amount of bone tissue per unit volume. In most cases of osteoporosis, the loss of bone tissue is mainly due to increased bone resorption. The onset is mostly slow, and individual is quicker. It is characterized by bone pain and easy fracture, and the biochemical examination is basically normal. [0003] At present, the treatment of this disease mainly relies on drug therapy, which generally includes estrogen replacement therapy, calcitonin and calcium preparations. Most ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/537A61P19/10
CPCA61K36/537A61K9/145A61K9/1652A61K9/2059A61K9/4858A61K36/28A61K36/35A61K36/484A61K36/52A61K2300/00
Inventor 李文军骆均勇成建国
Owner CHENGDU GUORUI PHARMA TECH
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